Conn's Translational Neuroscience

Table of Contents

1. Cytology of the Central Nervous System 2. Ion Channels 3. Neurotransmitters and Neurotransmission in the Developing and Adult Nervous System 4. Synaptic Development 5. The Peripheral and Central Nervous System 6. The Blood-Brain Barrier: A Restricted Gateway to the Brain 7. Autoregulation of Cerebral Blood Flow 8. The Vestibular System 9. The Cerebellum 10. The Basal Ganglia 11. Choroid Plexus-Cerebrospinal Fluid Transport Dynamics: Support of Brain Health and a Role in Neurotherapeutics 12. The Cerebral Cortex 13. The Thalamus 14. Cranial Nerves and Brainstem 15. Hypothalamic-Pituitary Regulation 16. Neuroendocrinimmunology: A Primer 17. The Olfactory System 18. Intranasal Trigeminal Chemoreception 19. Vision 20. Oculomotor Systems and Control 21. A Modern Clinicopathological Approach to Traumatic Brain Injury 22. Posttraumatic Stress Disorder 23. Somatosensation and Pain 24. Neurogenesis as a Factor in the Functional Plasticity of the Nervous System 25. Axonal Degeneration and Regeneration in the Peripheral and Central Nervous Systems 26. Audition 27. Body Clocks in Health and Disease 28. The Experience of Consciousness 29. The Emotional Brain 30. Stress, Mood, and Pathways to Depression 31. Language Processing, Development and Evolution 32. Memory 33. Neurobiology of Drugs of Abuse

Authors

P. Michael Conn Robert C. Kimbrough, III, MD, Professor of Medical Education, Texas Tech University Health Sciences Center, Lubbock, TX, USA. Dr. P. Michael Conn is the Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center. He is The Robert C. Kimbrough, Professor of Internal Medicine and Cell Biology/Biochemistry. He was previously Director of Research Advocacy and Professor of Physiology and Pharmacology, Cell Biology and Development and Obstetrics and Gynecology at Oregon Health and Science University and Senior Scientist of the Oregon National Primate Research Center. He served for twelve years as Special Assistant to the President and Associate Director of the ONPRC. After receiving a B.S. degree and teaching certification from the University of Michigan (1971), a M.S. from North Carolina State University (1973), and a Ph.D. degree from Baylor College of Medicine (1976), Conn did a fellowship at the NIH, then joined the faculty in the Department of Pharmacology, Duke University Medical Center where he was promoted to Associate Professor in 1982. In 1984, he became Professor and Head of Pharmacology at the University of Iowa College of Medicine, a position he held for eleven years. Conn is known for his research in the area of the cellular and molecular basis of action of gonadotropin releasing hormone in the pituitary and therapeutic approaches that restore misfolded proteins to function. His lab is credited with the first demonstrations of GPCR internalization and oligomerization. His work has led to drugs that have benefitted humans and animals. Most recently, his lab identified a new class of drugs, pharmacoperones, which act by regulating the intracellular trafficking of receptors, enzymes and ion channels. He has authored or co-authored over 350 publications and written or edited over 225 books, including texts in neurosciences, molecular biology and endocrinology. Conn has served as the editor of (Endocrinology, Journal of Clinical Endocrinology and Metabolism, Endocrine, Methods, Progress in Molecular Biology and Translational Science and Contemporary Endocrinology). The work of his laboratory has been recognized with a MERIT award from the NIH, the J.J. Abel Award of the American Society for Pharmacology and Experimental Therapeutics, the Weitzman, Oppenheimer and Ingbar Awards of the Endocrine Society, the Miguel Aleman Prize of Mexico and the Stevenson Award of Canada. He is the recipient of the Oregon State Award for Discovery, the Media Award of the American College of Neuropsychopharmacology and was named a distinguished Alumnus of Baylor College of Medicine. Conn is a previous member of Council for the American Society for Cell Biology and the Endocrine Society and is a prior President of the Endocrine Society, during which time he founded the Hormone Foundation.