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Radical Reactions for Organic Synthesis. A Practical Guide

  • Book

  • 350 Pages
  • December 2020
  • John Wiley and Sons Ltd
  • ID: 3699187
Filling a gap in the market for a practical guide on the topic, this book presents a selection of the most important and useful radical reactions applied in modern organic synthesis.
The chapters are arranged according to the reaction type, with each reaction briefly summarized with a special emphasis on its scope and limitations. Sample experimental procedures are also provided for each reaction, enabling readers to quickly become familiar with a new reaction.
With the authors reading like a who′s who in radical chemistry, this is an indispensable reference for all synthetic chemists in academia and industry.

Table of Contents

RADICAL CHAIN REACTIONS
Dehalogenation and Related Processes
Intermolecular C–C Bond Formation
Intermolecular C–X Bond Formation
Cyclizations
Rearrangements
RADICAL NON–CHAIN REACTIONS
OXIDATIVE PROCESSES
REDUCTIVE PROCESSES

Authors

Philippe Renaud is a Professor of Organic Chemistry at the University of Berne, Switzerland, since 2001. He received his Diploma at the University of Neuchâtel, Switzerland, in 1983 and then joined the ETH Zurich to obtain his Ph.D. degree under the supervision of Dieter Seebach in 1986. From October 1986 to December 1987 he was a postdoctoral associate of Marye Anne Fox at the University of Texas in Austin (USA). In 1988, he started an independent research program at the University of Lausanne and then moved to the University of Fribourg to become an associate professor in 1993. His research interests include radical chemistry, organometallic chemistry and total synthesis of natural products and alkaloids.

Mukund P. Sibi is a Distinguished Professor and James A. Meir Professor at North Dakota State University, USA, and the director for the Center for Protease Research at the same university. He received his Bachelor′s and Master′s degrees from Bangalore University, India, and then joined City University of New York, USA, to obtain his Ph.D. degree under the guidance of Robert Lichter in 1980. After postdoctoral studies with Gordon Gribble (Dartmouth College, USA, 1980–1982), Victor Snieckus (University of Waterloo, USA, 1982–1985) and Robert Holton (Florida State University, USA), he became an assistant professor at North Dakota State University in 1987. His research interests include total synthesis of natural products, radical chemistry, chiral catalysis, conversion of biomass to chemicals, and non–food uses of agricultural materials.