Protein-Protein Interactions in Human Disease, Part B. Advances in Protein Chemistry and Structural Biology Volume 111

Table of Contents

1. Homo- and Heterodimerization of Proteins in Cell Signaling: Inhibition and Drug Design Sitanshu S. Singh and Seetharama D. Jois 2. Targeting Intramembrane Protein-Protein Interactions: Novel Therapeutic Strategy of Millions Years Old Alexander B. Sigalov 3. Targeting the Architecture of Deregulated Protein Complexes in Cancer Eduard Stefan, Jakob Troppmair and Klaus Bister 4. Multifaceted Nucleolin Protein and Its Molecular Partners in Oncogenesis Iva Ugrinova, Maria Petrova, Mounira Chalabi-Dchar and Philippe Bouvet 5. Subcellular Targeting of Nitric Oxide Synthases Mediated by Their N-Terminal Motifs Carlos Costas-Insua, Javier Merino-Gracia, Clara Aicart-Ramos and Ignacio Rodríguez-Crespo 6. Development of Protein-Protein Interaction Inhibitors for the Treatment of Infectious Diseases Andrew F. Voter and James L. Keck 7. Defining Pharmacological Targets by Analysis of Virus-Host Protein Interactions Manuel Llano and Mario A. Peña-Hernandez 8. Investigating the Influence of Hotspot Mutations in Protein-Protein Interaction of IDH1 Homodimer Protein: A Computational Approach D. Thirumal Kumar, P. Sneha, Jennifer Uppin, S. Usha and C. George Priya Doss 9. Human Interactomics: Comparative Analysis of Different Protein Interaction Resources and Construction of a Cancer Protein-Drug Bipartite Network Javier De Las Rivas, Diego Alonso-López and Mónica M. Arroyo