Apprentices to Genius: A tribute to Solomon H. Snyder, a volume in the Advances in Pharmacology series, presents a tribute to Dr. Solomon H. Snyder, highlighting chapters submitted from a broad range of his students. It covers many different areas of neuroscience and pharmacology, with this volume exploring how receptor binding and drug discovery, the emerging role of glutamate in the pathophysiology of mental illness, nitric oxide signaling in neurodegeneration and cell death, carboxypeptidase E and the identification of novel neuropeptides as potential therapeutic targets, the regulation of mitochondrial functions by TSPO, clozapine and its translational investigation, and more.
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1. Multiple Pathways Mediate MicroRNA Degradation: Focus on the Translin/Trax RNase Complex Jay M. Baraban, Aparna Shah and Xiuping Fu 2. Receptor Binding Assays and Drug Discovery David B. Bylund and Sam J. Enna 3. The Role of Serine Racemase in the Pathophysiology of Brain Disorders Joseph T. Coyle and Darrick T. Balu 4. Nitric Oxide Signaling in Neurodegeneration and Cell Death Ted M. Dawson and Valina L. Dawson 5. Carboxypeptidase E and the Identification of Novel Neuropeptides as Potential Therapeutic Targets Lloyd D. Fricker 6. Regulation of Mitochondrial, Cellular, and Organismal Functions by TSPO Moshe Gavish and Leo Veenman 7. Unique Effects of Clozapine: A Pharmacological Perspective Jibran Y. Khokhar, Angela M. Henricks, Emily Kirk and Alan I. Green 8. Imaging Translocator Protein as a Biomarker of Neuroinflammation in Dementia William C. Kreisl, Ioline D. Henter and Robert B. Innis 9. RNA-Based Fluorescent Biosensors for Detecting Metabolites In Vitro and in Living Cells Samie R. Jaffrey 10. Phosphorylation of the Amino Terminus of the Dopamine Transporter: Regulatory Mechanisms and Implications for Amphetamine Action Caline S. Karam and Jonathan A. Javitch 11. Anti-NMDA Receptor Encephalitis: Clinical Features and Basic Mechanisms David R. Lynch, Amy Rattelle, Yi Na Dong, Kylie Roslin, Amy J. Gleichman and Jessica A. Panzer 12. Mu Opioid Pharmacology: 40 Years to the Promised Land Gavril W. Pasternak 13. Synaptotoxic Signaling by Amyloid Beta Oligomers in Alzheimer's Disease Through Prion Protein and mGluR5 A. Harrison Brody and Stephen M. Strittmatter 14. The Neurobiology of d-Serine Signaling Herman Wolosker