Neuroinflammation, Second Edition, discusses the role inflammation plays in neuro-inflammatory diseases. As research in neuroinflammation has dramatically increased in recent years, this new edition covers all of the new developments and findings since the first publication nearly a decade ago. Comprehensive coverage of topics includes chapters on multiple sclerosis, optic neuritis and Susac syndrome. New chapters cover the latest research in Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury, amongst other topics.
Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, brain trauma and meningitis, and it contributes to the generation of pain. Researchers are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage, through tolerance, and to modulation and repair.
- Comprehensively reviews the latest developments in neuroinflammation and neuro-inflammatory diseases
- Written for researchers and clinical practitioners in clinical neuroscience, neurology and immunology
- Includes new chapters on Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury
1. Multiple Sclerosis: Pathophysiology, Clinical Features, Diagnosis, and Management 2. Role of viruses in pathophysiology of multiple sclerosis 3. Neutralizing Antibodies and Multiple Sclerosis 4. Animal Models of Multiple Sclerosis 5. Neuroimaging of Multiple Sclerosis and other immune-mediated diseases of central nervous system: An Update 6. Role of IL-12/IL-23 in the Pathogenesis of Multiple Sclerosis 7. Spinal Cord Injury and its Relationship to the Development or Worsening of Clinical Multiple Sclerosis or Transverse myelitis 8. Monoclonal antibodies in treatment of multiple sclerosis New authors 9. Remyelination in Multiple Sclerosis 10. Role of vitamin D in pathogenesis and treatment of multiple sclerosis 11. Autoimmune encephalitis 12. Epilepsy and neuroinflammation 13. Neurosarcoidosis 14. Existing and emerging therapies for multiple sclerosis 15. Viral infections of central nervous system: Clinical presentation, pathophysiology and treatment 16. Tumefactive multiple sclerosis: Clinical presentation, pathophysiology and treatment options 17. Pediatric multiple sclerosis 18. Acute disseminate encephalomyelitis: Clinical presentation, pathophysiology, neuroimaging and treatment options 19. Transverse Myelitis) 20. Neuromyelitis Optica 21. Optic Neuritis: Pathophysiology, Clinical Features, and Management-Ischemic Demyelination-Tiffany Chang, Roger E. Kelley 22. Inflammatory Mechanisms in Ischemic Cerebrovascular Disease 23. Protection Against Neuroinflammation by Promoting Co-activation of G Protein-Growth Factor Signaling and Metabolic Flexibility in the Brain 24. Mesenchymal Stem Cells, Inflammation, and Neurodegenerative Diseases 25. Inflammatory Mediators in Obstructive Sleep Apnea 26. The Role of Neuroinflammation in Parkinson's Disease-Xi Chen, Malú G. Tansey 27. Neuroinflammation and Pediatric Lupus 28. Central Nervous System Vasculitis 29. Systemic Lupus Erythematosus-Vasculopathy/Vasculitis, Susac Syndrome, and Myasthenia Gravis 30. Inflammatory Mechanisms in Guillain-Barré Syndrome 31. Neurologic Manifestations of Herpes Zoster 32. Roles of macrophages and astrocytes in pathogenesis of multiple sclerosis 33. Blood brain disintegration in pathogenesis of multiple sclerosis 34. Neuroinflammatory mechanisms in pathogenesis of Alzheimer's disease 35. HIV infection of the nervous system: Clinical features, pathogenesis and treatment 36. Bacterial meningitis: Clinical presentation, Pathophysiology and treatment 37. Role of Toll like receptors in neuroinflammation 38. Role of neuroinflammation in pathophysiology of traumatic brain injury 39. Fatty acids as inflammatory mediators in the ischemic brain 40. Chronic cerebrospinal venous insufficiency in multiple sclerosis 41. Brain lymphatic system
Dr. Minagar is a Professor of Neurology at LSU Health Sciences Center in Shreveport, Louisiana. He's a certified Physician Investigator by Association of Clinical Research Professionals, member of the editorial board of Future Neurology, Neurological Research, and Alzheimer's Disease Research Board. Dr. Minagar is the author of 231 journal articles and 33 book chapters, and editor of 10 books.