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Vaccines for Cancer Immunotherapy. An Evidence-Based Review on Current Status and Future Perspectives

  • Book

  • October 2018
  • Elsevier Science and Technology
  • ID: 4465320

Therapeutic cancer vaccines represent a type of active cancer immunotherapy. Clinicians, scientists, and researchers working on cancer treatment require evidence-based and up-to-date resources relating to therapeutic cancer vaccines. Vaccines for Cancer Immunotherapy provides a reference for cancer treatment for clinicians and presents a well-organized resource for determining high-potential research areas. The book considers that this promising modality can be made more feasible as a treatment for cancer. Chapters cover cancer immunology, general approaches to cancer immunotherapy, vaccines, tumor antigens, the strategy of allogeneic and autologous cancer vaccines, personalized vaccines, whole-tumor antigen vaccines, protein and peptide vaccines, dendritic cell vaccines, genetic vaccines, candidate cancers for vaccination, obstacles to developing therapeutic cancer vaccines, combination therapy, future perspectives and concluding remarks on therapeutic cancer vaccines.

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Table of Contents

1. Cancer immunology 2. Immunotherapeutic Approaches in Cancer 3. Vaccines, Adjuvants, and Delivery Systems 4. Tumor Antigens 5. Strategy of Allogeneic and Autologous Cancer Vaccines 6. Personalized Cancer Vaccine 7. Whole Tumor Cell Vaccine for Cancer 8. Peptide and Protein Vaccines for Cancer 9. Immune Cell Vaccine for Cancer 10. Genetic Vaccine for Cancer 11. Candidate Cancers for Vaccination 12. Obstacles in the Development of Therapeutic Cancer Vaccines 13. Combination Therapy: Cancer Vaccines and Other Therapeutics 14. Concluding Remarks and Future Perspectives on Therapeutic Cancer Vaccines


Nima Rezaei Professor of Clinical Immunology, Research Center for Immunodeficiencies, Children's Medical Center and Department of Immunology, School of Medicine, Tehran University of Medical Sciences; Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran. Nima Rezaei is professor of immunology at Tehran University of Medical Sciences. He is a well-known scientists and researcher with over 1000 academic publications including papers and books. He is an expert researcher who has trained many students over the past decade. Mahsa Keshavarz-Fathi Medical Researcher, Tehran University of Medical Sciences, Tehran. Mahsa Keshavarz-Fathi is a medical researcher and MD candidate at Tehran University of Medical Sciences (TUMS). She is also the managing director of the Cancer Immunology Project (CIP) and Breast Cancer Association (BrCA) undertaking and managing different research projects in the field of cancer treatment, cancer immunology and immunotherapy.