Quality Control and Evaluation of Herbal Drugs

  • ID: 4519370
  • Book
  • 700 Pages
  • Elsevier Science and Technology
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Quality Control and Evaluation of Herbal Drugs: Approaches for Evaluating Natural Products and Traditional Medicine brings together current thinking and practice in the quality control and standardization of herbal drugs. As the use of herbal medicine in therapeutics is rising in both developed and developing countries, this book facilitates the development of quality standards for these medicines. Written by Pulok K. Mukherjee, a leader in the field, the book describes methods, techniques and approaches for evaluating their purity, quality, safety and efficacy. Particular attention is paid to methods that assess activity, the compounds responsible, and their underlying mechanisms of action.

The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, Sri Lanka and other Asian countries, as well as the regulatory profiles of the European Union and North America. Users will find it to be a comprehensive resource on bio-prospecting for traditional-medicine-inspired drug discovery and development.

  • Provides new information on the research and development of natural remedies
  • Includes essential reading on the study and use of natural resources for preventative or healing purposes
  • References global organizations, such as the WHO, USFDA, CDSCO, TCM and others to serve as a comprehensive document for enforcement agencies, NGOS and regulatory authorities
  • Aids in developing basic knowledge of the various techniques of quality evaluation, such as macroscopy, microscopy, HPTLC, HPLC and LC-MS
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1. Traditional systems of medicines and harmonization
2. Ethnopharmacology- and ethnomedicine-inspired drug development
3. Quality evaluation of herbal medicines: Challenges and opportunities
4. Qualitative analysis for evaluation of herbal drugs
5. Morphological and microscopical evaluations
6. Extraction and other downstream procedures for evaluation of herbal drugs
7. Bioactive phyto-components and their analysis
8. Thin layer chromatography for evaluation of herbal drugs
9. High performance thin layer chromatography (HPTLC) for analysis of herbal drugs
10. High performance liquid chromatography for analysis of herbal drugs
11. LC-MS: A rapid technique for understanding the plant metabolomic analysis
12. Chemo-profiling and marker analysis for quality evaluation of herbal drugs
13. Bioassay guided isolation and evaluation of herbal drugs
14. Enzyme inhibition studies for evaluation of herbal drugs
15. Evaluation of herbal drugs for antimicrobial and parasiticidal effects
16. Antiviral evaluation of herbal drugs
17. Plant metabolomics and quality evaluation of herbal drugs
18. Safety related quality issues for development of herbal drugs
19. Quality assurance of herbal drugs and stability testing
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Mukherjee, Pulok K.
Professor Pulok K. Mukherjee is a Fellow of the Royal Society of Chemistry and the Director of the School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. He has made significant contributions in the area of evaluation and validation of medicinal plants, ethno-pharmacology, and ethno-medicine. His work on integrated approaches for traditional-medicine-inspired drug development through chemo-profiling, quality control, and standardization of herbal drugs has achieved worldwide acclaim. He has contributed over 200 publications in peer reviewed impact journals and has several patents. He has also published several well acclaimed books including Evidence-Based Validation of Herbal Medicine (Elsevier); Evaluation of Herbal Medicinal Products (Pharmaceutical Press), and many others. He has been honored with several awards and laurels from both the Government of India and abroad. For further details please visit www.pulokmukherjee.in.
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