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Medicinal Plants, Phytomedicines and Traditional Herbal Remedies for Drug Discovery and Development against COVID-19

  • Book

  • November 2023
  • Bentham Science Publishers Ltd
  • ID: 5921139
This comprehensive reference explores medicinal plants, phytomedicines, and traditional herbal remedies as potential sources for the prevention and treatment of COVID-19. It features 9 chapters authored and edited by renowned experts. The book specifically highlights the promising drug discovery opportunities grounded in bioactive compounds from medicinal plants and herbal medicines, offering insights into combatting SARS-CoV-2 infections and respiratory complications.

Key Highlights:

  • Drug Discovery Potential: Explores the vast potential of medicinal plants, phytomedicine, and traditional remedies against COVID-19, shedding light on groundbreaking drug discovery avenues.
  • Cutting-Edge Insights: Provides up-to-date insights into the use of medicinal plants, herbal drugs, and traditional medicines in the fight against COVID-19.
  • Natural Immune Boosters: Details the use of indigenous herbs, spices, functional foods, and herbal drugs for boosting immunity and preventing SARS-CoV-2 infections.
  • Drug Repurposing: Highlights innovative drug repurposing strategies using phytomedicine-derived bioactive compounds and phytochemical databases for COVID-19 drug development.
Additional features of the book include a reader-friendly introduction to each topic and a list of references for advanced readers. This timely reference is an informative resource for a broad range of readers interested in strategies to control COVID-19, including postgraduate researchers, and pharmaceutical R&D experts. It also serves as a handbook for professionals in clinical and herbal medicine.

Audience

Postgraduate researchers, and professionals in clinical and herbal medicine; drug discovery scientists.

Table of Contents

Chapter 1 Phytoconstituents from Mother Nature Against Sars-Cov-2/
  • Covid-19
  • Neelesh Kumar Nema, Swapnil Devidas Khamborkar, Smitha Sarojam, Baby
  • Kumaranthara Chacko and Viju Jacob
  • Introduction
  • Materials and Methods
  • Sars-Cov-2 and Phytoconstituents Data Collection
  • Information Evaluation
  • Results
  • Sars-Cov-2 and Ethnomedicinal Plants
  • Sars-Cov-2 Morphological Features and Structure
  • Sars-Cov-2 Replication in the Host Cells
  • Interactions With the Host Cell
  • Fusion of Genomes
  • Replication (Transcription and Translation)
  • Exit from the Host Cell
  • Targets for Therapeutic Intervention
  • Pre-Viral Infection Targeted Approaches
  • Post-Viral Infection Targeted Approaches
  • Sars-Cov-2 Replication
  • Immunomodulatory Targets
  • Solutions for the Treatment
  • Medicinal Plants from Mother Nature
  • Andrographis Paniculata
  • Azadirachta Indica
  • Cinnamomum Verum
  • Clerodendrum Serratum
  • Curcuma Longa
  • Cymbopogon Jwarancusa
  • Glycyrrhiza Glabra
  • Hedychium Spicatum
  • Inula Racemosa
  • Justicia Adhatoda
  • Illicium Verum
  • Ocimum Basilicum & Ocimum Tenuiflorum
  • Phyllanthus Emblica
  • Pichrorhiza Kurroa
  • Swertia Chirata
  • Syzygium Aromaticum
  • Tinospora Cordifolia
  • Withania Somnifera
  • Zingiber Afficinale
  • Discussion
  • Conclusion
  • Abbreviations
  • References
Chapter 2 Role of Medicinal Plants and Phytomedicine Against Covid-
  • 19 Management
  • Kunika Saini, Smriti Sharma and Vinayak Bhatia
  • Introduction
  • Transmission and Life Cycle of Sars-Cov-2
  • Life Cycle of Sars-Cov-2
  • Drug Discovery Strategies Against Sars-Cov-2 Infection
  • An Outline of Covid-19 Therapeutics and Drugs
  • Drug Design Strategies Against Covid-19
  • Role of Phytomedicine in Treating Sars-Cov-2 Infection
  • Phytomedicine: the Gold Mine for Designing Novel Drugs
  • The Potential of Medicinal Plants for Treating Covid-19
  • Ayurvedic Approaches
  • Unani Approaches
  • Siddha Approaches
  • Medicinal Plants for Treating Covid-19: Current Status
  • Conclusion and Future Perspectives
  • References
Chapter 3 Immune Foods for Fighting Coronavirus Disease-2019 (Covid-19)
  • Chinaza Godswill Awuchi, Hannington Twinomuhwezi, Chibueze Gospel
  • Awuchi, Ikechukwu O. Amagwuala and Chukwuebuka Egbuna
  • Introduction
  • Role of Foods Constituents in Immune System Functions
  • Macronutrients and Their Immune Functions
  • Micronutrients and Their Immune Functions
  • Food Components, Nutrients, and Covid-19
  • Immune Boosting Micronutrients Against Covid-19 (Sars-Cov-2)
  • Vitamins for Fighting Covid-19
  • Minerals for Fighting Covid-19
  • Actions of Bioactive Compounds in Foods Against Covid-19 (Sars-
  • Cov-2)
  • Food, Obesity, Immunity, and Covid-19
  • Conclusion
  • References
Chapter 4 Plant Sources of Pro and Anti-Inflammatory Mediators
  • Against Covid-19
  • Iqra Yasmin, Wahab A. Khan, Ayesha Manzoor, Muhammad W. Iqbal And
  • Muhammad Azam
  • Introduction
  • Pro-Inflammatory and Anti-Inflammatory Mediators from Fruits and Vegetables
  • Health Benefits
  • In Vitro and in Vivo Studies of Fruits and Vegetables Against Inflammation
  • Pro-Inflammatory and Anti-Inflammatory Mediators from Legumes
  • Conclusion
  • References
Chapter 5 Drug Therapies Against Acute Respiratory Distress: A
  • Critical Endpoint of Covid-19
  • Maha M. Salama, Rana M. Merghany, Ahmed Zayed, Mohamed A. Salem And
  • Shahira M. Ezzat
  • Introduction
  • Characteristics of Human Coronaviruses and Sars-Cov- 2
  • Contribution of the Inflammatory Pathways to the Pathogenesis
  • Of Acute Respiratory Distress and Covid-19
  • Current Management of Covid-19
  • Antiviral Drugs Approved/Under Assessment for the Treatment of Covid-19
  • Antithrombotic Therapy in Patients Covid-19 (With Anticoagulants And/Or Antiplatelet
  • Drugs)
  • Anti-Coagulant Therapy
  • Anti-Platelet Therapy
  • Cell-Based Therapy for the Treatment of Covid-19 (Under Assessment)
  • Reported Clinical Trials on Mesenchymal Cells for Covid-19
  • Immunomodulatory/Anti-Cytokine Therapies
  • Convalescent Plasma
  • Anti-Cytokine Therapies
  • Intravenous Immunoglobulin Therapy
  • Anti-Inflammatory Therapy
  • Corticosteroids
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
  • Herbal Medicines Alleviating Acute Respiratory Infection
  • Echinacea Purpurea
  • Portulaca Oleracea
  • Eucalyptus Globulus
  • Glycyrrhiza Glabra
  • Curcuma Longa
  • Thymus Vulgaris
  • Taraxacum Sp.
  • Ginkgo Biloba
  • Radix Bupleuri
  • Herbal-Derived Natural Products in Boosting the Body’S Immunity
  • Conclusion
  • References
Chapter 6 Medicinal Spices for the Prevention and Treatment Of
  • Coronavirus Disease-2019
  • Muhammad Akram, Rabia Anum, Walaa Fikry Elbossaty, Chukwuebuka
  • Egbuna, Chinaza Godswill Awuchi, Chukwuemelie Zedech Uche, Kingsley C.
  • Patrick-Iwuanyanwu, Soumya Bhattacharya and Mithun Rudrapal
  • Introduction
  • Medicinal Plant Spices and Herbs for Covid-19
  • Ginger
  • Garlic
  • Fenugreek
  • Black Pepper
  • Clove
  • Red Chilli Peppers
  • Curcumin
  • Nigella Sativa
  • Fennel
  • Onion
  • Nutmeg
  • Cinnamon
  • Cinnamomum Tamala
  • Cardamum
  • Ajwain
  • Moringa Oleifera Lam
  • Conclusion
  • References
Chapter 7 Boosting Host Immunity to Combat Coronavirus Disease-2019
  • (Covid-19)
  • Mithun Rudrapal, Soumya Bhattacharya and Dipak Chetia
  • Introduction
  • Current Therapeutic and Prophylactic Interventions
  • Immune Inflammatory Responses to Sars-Cov-2 Infection
  • Boosting Host Immunity: Dietary, Herbal and Alternative
  • Approaches
  • Diet and Foods
  • Natural Foods
  • Fruits and Vegetables
  • Food Spices
  • Herbs and Herbal Drugs
  • Immunomodulatory Herbs
  • Antiviral Herbs
  • Herbs With Other Healing Properties
  • Yoga and Naturopathy
  • Conclusion
  • References
Chapter 8 Functional Foods, Herbal Supplements and Nutraceuticals
  • In the Management of Coronavirus Disease-2019 (Covid-19)
  • Santwana Palai and Mithun Rudrapal
  • Introduction
  • Epidemiology of Covid-19
  • Dietary Immunomodulators in Covid-19 Management
  • Functional Foods, Herbal Supplements and Nutraceuticals In
  • Diseases Management
  • Beneficial Effects of Antiviral/Immunomodulatory Functional
  • Food in the Management of Covid-19
  • Beneficial Effects of Herbal Supplements/ Phytoconstituents/
  • Nutraceuticals for Respiratory Ailments/ Infections in The
  • Management of Covid-19
  • Beneficial Effects of Immunomodulating Nutraceuticals In
  • Management of Covid-19
  • Future Perceptive
  • Conclusion
  • Abbreviations
  • References
Chapter 9 Aromatic Plants, Essential Oils, Carminatives, Tea Plants
  • And Expectorant Herbs for the Management of Covid-19

Author

  • Mithun Rudrapal
  • Chukwuebuka Egbuna