Non-Enzymatic Protein Modifications in Health, Diseases and Ageing discusses each type of non-enzymatic protein, introducing non-enzymatic protein modifications, reviewing the state-of-the-art, and presenting updates and current trends. The book covers various aspects of the subject, including the formation and removal of modified proteins, their roles in disease, preventative methods, and possible roles in cellular signaling. This book not only provides well-established facts, but also discusses current hypotheses and controversies.
- Provides the basic chemical knowledge necessary to understand non-enzymatic protein modifications
- Combines a systematic chemical introduction to non-enzymatic protein modifications
- Presents the types of non-enzymatic proteins that are usually separately reported and reviewed
- Considers current hypotheses and controversies alongside the facts
Table of Contents
1. Chemistry of non-enzymatic protein modifications2. Methods for detection and quantification of non-enzymatic protein modifications
3. Non-enzymatic protein modifications under physiological conditions
4. Possible role of non-enzymatic protein modifications in cellular signalling
5. Altered non-enzymatic protein modifications in diseases and their pathogenic roles
6. Accumulation of products of non-enzymatic protein modification in aging and their potential role in aging
7. Prevention of non-enzymatic protein modifications and of their effects
8. Non-enzymatic protein modifications during food and feed preparation and storage, and their effect on food and feed quality
9. Summary: what to expect?
