The Exposome: A New Paradigm for the Environment and Health, Second Edition, is a thoroughly expanded and updated edition of The Exposome: A Primer, the first book dedicated to the topic. This new release outlines the purpose and scope of this emerging field of study, its practical applications, and how it complements a broad range of disciplines. The book contains sections on -omics-based technologies, newer detection methods, managing and integrating exposome data (including maps, models, computation and systems biology), and more. Both students and scientists in toxicology, environmental health, epidemiology and public health will benefit from this rigorous, yet readable, overview.
This updated edition includes a more in-depth examination of the exposome, including full references, further reading and thought questions.
- Addresses an emerging field that connects with other exciting disciplines
- Written by a single author who is a leader in the field
- Includes new content that widely expands on the first edition
1. Introduction: The Need of the Exposome 2. Genes, genomes and genomics: A Historical Perspective of Genomics up to Modern Day Advances 3. What is nurture? 4. The Environment: The Good, the Bad and the Ugly 5. Collecting Exposure Information, Signals, Noise and Noise-Measure 6. Technological Issues 7. Exposome and Pathways 8. Big Data for the Exposome 9. The Exposome in the Community 10. The Exposome in Large Human Studies 11. The Exposome in the Future
Gary W. Miller, PhD is the Vice Dean for Research Strategy and Innovation and Professor of Environmental Health Sciences at the Mailman School of Public Health at Columbia University. He was founding director of the HERCULES Exposome Research Center at Emory University, the first exposome-based center in the U.S. In addition to his work on the exposome, his research interests include the role of environmental factors in neurodegenerative disorders, such as Parkinson's disease and Alzheimer's disease, and the regulation of dopamine signaling in the brain. He served as Editor-in-Chief of Toxicological Sciences, the official journal of the Society of Toxicology, from 2013-2019.