Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders, Vol 241. Progress in Brain Research

  • ID: 4540093
  • Book
  • 358 Pages
  • Elsevier Science and Technology
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Genetic Models and Molecular Pathways Underlying Autism Spectrum Disorders, Volume 241 provides the most recent information on the animal model systems that are available to study different forms of autism spectrum disorders. In addition to genetically engineered animals that uniquely model genetic forms of ASD, this volume also provides detailed chapters on a variety of specific topics, including An overview of genetic models of ASDs, Phenotypic modeling of ASD symptoms, Molecular mechanisms of NF1 model of ASD symptoms, Ube3a gene dosage disorders: molecular and circuit mechanisms of ASD, Circuit dysfunctions in ASD models, ERK signaling in genetic models of ASD, and more.

  • Presents a timely, comprehensive assessment of the field
  • Includes helpful summaries on current knowledge, gaps and future directions in autism research
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1. Introduction Anantha Shekhar 2. Overview of genetic models of ASDs Anantha Shekhar 3. Phenotypic modeling of ASD symptoms Kathryn K. Chadman 4. Molecular mechanisms of NF1 model of ASD symptoms Andre Molosh 5. Ube3a gene dosage disorders: molecular and circuit mechanisms of ASD Matthew Anderson 6. Circuit dysfunctions in ASD models Molly Maureen Huntsman 7. ERK signaling in genetic models of ASD Gary Landreth 8. Translating ASD models from bench to bedside Anantha Shekhar 9. Studying child development in genetic models of ASD Jonathan Green 10. Clinical trial methodologies for genetic forms of autism Karin Walsh
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