The Common Marmoset in Captivity and Biomedical Research. American College of Laboratory Animal Medicine

  • ID: 4579841
  • Book
  • Region: United States
  • 925 Pages
  • Elsevier Science and Technology
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The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species, filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the American College of Laboratory Animal Medicine as part of its Blue Book series, the book covers the biology and management, diseases and clinical applications, and research. The common marmoset (Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced, small, prolific and easily maintained nonhuman primate with many of the advantages of larger animals, such as macaques, but without the attendant physical and zoonotic risks.

Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. The marmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primate model with which to study a number of disorders, like autism, which have yet to be substantively understood.

  • Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research and applications
  • Includes contributions from world-renowned editors
  • Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series
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Section I: Biology and Management 1. Taxonomy and Natural History 2. Anatomy and Physiology of the Marmoset 3. Neuroanatomy of the Marmoset Brain 4. Nutrition 5. Housing and Management 6. Normal Clinical and Biological Parameters 7. Behavior and Behavioral Management 8. Growth, Reproduction and Breeding 9. Regulatory Considerations

Section II: Diseases and Clinical Applications 10. Physical Examination and Diagnosis 11. Anesthesia and Common Surgical Procedures 12. Reproductive Biology and Disease 13. Diseases of the Gastrointestinal System 14. Bone, Muscle and Skeletal Disease 15. Viral Diseases 16. Bacterial, Mycoplasmal, and Mycotic diseases 17. Parasitic Diseases 18. Neoplastic Diseases

Section III:  Research and Applications 19. The Genome of the Common Marmoset 20. Creating Transgenic Marmosets 21. Marmosets in Aging Research 22. Marmosets in Neuroscience 23. Marmosets in Toxicology 24. Marmosets in Infectious Disease Research 25. Marmosets in Endocrine Research

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Marini, Robert P.
Robert P. Marini, DVM, DACLAM, Assistant Director, is a member of MIT's Division of Comparative Medicine's clinical staff and is Chief of the Division's clinical surgical facilities. Dr. Marini is responsible for coordinating and supervising all major survival surgery in non-rodent mammalian species.
Wachtman, Lynn M.
Harvard Medical School, Boston MA USA
Tardif, Suzette D.
Suzette D. Tardif, Ph.D., is the Associate Director of Research at the Southwest National Primate Research Center. She is an adjunct faculty of The Barshop Institute. The Tardif laboratory's activities center on the development of the marmoset monkey as a disease model. Dr. Tardiff is a past-President of the American Society of Primatologists.
Mansfield, Keith
Keith Mansfield is Associate Director for Resource and Collaborative Affairs and Chair, Division of Primate Resources, New England National Primate Research Center, Harvard Medical School, Harvard University, Southborough, US. His research focuses on primarily on the recognition of spontaneously occurring infectious diseases of nonhuman primates and their development into novel animal models to investigate disease pathogenesis.
Fox, James G.
James G. Fox, DVM, MS, DACLAM, is a Professor and Director of the Division of Comparative Medicine and a Professor in the Division of Biological Engineering at the Massachusetts Institute of Technology. He is also an Adjunct Professor at Tufts University School of Veterinary Medicine and the University of Pennsylvania, School of Veterinary Medicine. He is a Diplomate and a past president of the American College of Laboratory Animal Medicine, past president of the Massachusetts Society of Medical Research, past chairman of AAALAC Council, and past chairman of the NCCR/NIH Comparative Medicine Study Section. He also is an elected fellow of the Infectious Disease Society of America. Professor Fox is the author of over 490 articles, 80 chapters, 3 patents and has edited and authored 13 texts in the field of in vivo model development and comparative medicine.
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