Osseointegration of Orthopaedic Implants

Table of Contents

Part I General topics in osteointegration 1. Biology of bone tissue 2. History of osteointegration 3. Basic science research and clinical findings of osteointegration

Part II Overview of orthopedic implants 4. Implant loosening 5. Bone fracture fixation implants 6. Joint replacement prostheses 7. Tissue engineering scaffolds

Part III Biomaterials for enhancement of osteointegration 8. Osteoconductive materials 9. Osteoinductive materials 10. Bioactive materials

Part IV Surface treatments for enhancement of osteointegration 11. Bioactive coating 12. Porous surface 13. Surface treatment

Part V Biological concepts and challenges of osteointegration 14. Bone tissue in-growth and on-growth 15. Body fluid rate effect on osteointegration 16. Osteoinductivity and Osteoconductivity

Part VI Mechanical concepts and challenges of osteointegration 17. Load transferring mechanism between bone and implant 18. Osteointegration in long term implantation 19. Stress shielding effect on osteointegration 20. Biomechanical concepts of scaffolding

Part VII Novel development concepts 21. Novel development concepts of implant osteointegration 22. Transition layer concept 23. Improvement of long term bioactivity at transition layer 24. Enhancement of load transferring at transition layer 25. Development of shape memory concept at transition layer 26. Promoting osteointegration of physiological loading cycles at early implantation

Authors

Amirhossein Goharian Independent Engineering Consultant in Orthopaedic Implant and Biomaterial Industry, Isfahan, Iran. Amirhossein Goharian is a Senior Engineer working in the orthopedic implant industry. He earned his Bachelor's degree from the University of Kashan in 2007, and his completed his Master's in Mechanical Engineering in Biomechanics at the University Technology Malaysia (UTM) in 2012. He joined the R&D department of LEONIX Sdn. Bhd., Penang, Malaysia, in 2012, rising to Senior R&D Leader in Jan 2015. In 2017, he joined Isfahan Orthopedic Implant Development Co., an orthopedic implant manufacturer in Isfahan, Iran, as the QA-R&D leader until Sep 2020. Since then, he has been developing innovations in the field of orthopedic implants, based on ideas set out in his published work. Goharian has previously published three books with Elsevier, covering trauma plating systems, osseointegration and surface engineering of orthopedic implants.