The Wolff-Kishner Reduction and Related Reactions: Discovery and Development offers a detailed discussion of this reaction, its discoverers, and its development since its discovery. Derivative name reactions-including the Wharton and Shapiro reactions-are also discussed. The book is illustrated with examples from literature and corresponding references to the primary literature to aid further reading. It provides a comprehensive review of the century of chemistry that allows the reader to follow the development of this important synthetic reaction. In addition, it provides biographical details on the chemists who discovered and developed the reaction, thus adding a human dimension to the discussion.
- Introduces Wolff and Kishner, the discoverers of the reaction, along with Huang Ming-Long, the developer of an important modification of the reaction
- Discusses the discovery of the reaction and the way that priority for the discovery was settled between Wolff and Kishner
- Discusses, in depth, the development and usage of the reaction over the century, from its discovery, to its most recent applications and modifications in synthesis
- Includes biographical materials on the chemists responsible for major derivative name reactions based on the Wolff-Kishner reduction
2. Discovery and Priority
3. The First Two Decades: Mechanism and Early Use in Synthesis
4. To the End of World War II: Expanding the Use of the Reaction
5. After World War II
6. The Modern Wolff-Kishner Reduction
7. Use of the Reaction in Modern Synthesis
David E. Lewis is Professor of Chemistry at the University of Wisconsin-Eau Claire. He holds BSc, PhD, and DSc degrees from the University of Adelaide, in South Australia. His research over the last decade has been divided between synthetic organic chemistry and the history of chemistry (specifically, the history of organic chemistry in Russia). He is the author of Advanced Organic Chemistry (Oxford 2016) and of Early Russian Organic Chemists and Their Legacy (Springer Verlag 2012). He has presented seven plenary or invited lectures on the history of organic chemistry in Russia at conferences in Russia (Kazan, Ekaterinburg, and St. Petersburg). He is a member of the Editorial Advisory Board of Minireviews in Organic Chemistry, and of the ad hoc Editorial Advisory Board of The Bulletin for the History of Chemistry.