The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle provides the first comprehensive overview on the molecular methodologies used to evaluate sleep while also examining the cellular, biochemical, genetic, and therapeutic aspects of the sleep-wake cycle. There have been profound changes in the landscape of approaches to the study of sleep - mainly in the areas of molecular biology and molecular techniques. With this great focus on using multidisciplinary molecular methods, chapters address significant advances in the molecular mechanisms underlying sleep and the techniques researchers use to study this phenomenon.
Written by world-leading experts in the area, this book is of great interest to researchers working in the sleep field and to anyone interested in one of the most mysterious phenomena in science - why we sleep and why we cannot survive without it.
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1. The Sleep-Wake Cycle. An Overview 2. Multiple experimental approaches for studying the sleep-wake cycle 3. Phylogeny of Sleep 4. Neuromolecular Mechanism for Sleep Generation 5. Physiological Mechanism for Control of Waking 6. Pharmacology of Sleep 7. Electrophysiological correlates of the sleep-wake cycle 8. Sleep Disturbances 9. Obesity and sleep disturbances 10. Alcoholism and sleep
Dr. Murillo-Rodríguez is a psychologist and PhD in Biomedical Sciences, having completed his post-doctoral training at Harvard Medical School. He has served as editor of multiple journals such as The International Journal of Neuropsychopharmacology and PLoS ONE. He is a member of several scientific societies, including the Society for Neuroscience. He has received academic awards such as the Young Investigator Award from the World Federation of Sleep Research and Sleep Research Societies Society, and is a member of the National System of Researchers (Level 1) of the National Council of Science and Technology (México). He is also the author of The Endocannabinoid System: Genetics, Biochemistry, Brain Disorders, and Therapy (Elsevier, May 2017).