Molecular Nutrition: Carbohydrates presents the nutritional and molecular aspects of carbohydrates. As part of the Molecular Nutrition includes sections covering carbohydrate metabolism, carbohydrates in the diet, insulin resistance, dietary sugars, cardiometabolic risk, lipoproteins, low-carbohydrate diets, antioxidants, refined dietary sugars, fats, glucose transporters, glucose sensing, the role of phosphorylation, carbohydrate responsive binding protein, cyclic AMP, peroxisome proliferator-activated receptors, SIRT1, insulinotropic polypeptide (GIP) and GIP receptor (GIPR) genes rRNA and transcription, and more. In addition, the book addresses emerging fields of molecular biology and presents important discoveries relating to diet and nutritional health.
- Summarizes molecular nutrition in health as related to carbohydrates
- Addresses emerging fields of molecular biology and presents important discoveries relating to diet and nutritional health
- Includes key facts, a mini dictionary of terms and summary points
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Part 1. General and Introductory Aspects 1. Interrelationships between lipoproteins and carbohydrate in the diet Carmine Finelli 2. Molecular aspects and biochemical regulation of diabetes Daniel Gyamfi
Part 2. Molecular Biology of the Cell 3. Glucose transporters and their cellular form, role and function Archana Mohit Navale 4. Liquid fructose and liver insulin signalling: Molecular mechanisms controlling hepatic steatosis Marta Alegret 5. PPARg knockouts and glucose tolerance N.J.G. Webster 6. Dietary phenolic acids and metabolic syndrome Taofeek Ajiboye 7. Glucose Transporter 1 and Prognosis in Cancer Hideo Baba and Hiroshi Sawayama 8. Effects of dietary Salba on glucose metabolism in an experimental model of dyslipidemia and insulin resistance Y.B. Lombardo
Part 3. Genetic Machinery and Its Function 9. Nutrigenomics for personalized nutrition to prevent hyperglycemia and type 2 diabetes mellitus Kumpei Tanisawa 10. High fructose consumption and DNA methylation Hiroya Yamada 11. The GALT gene and galactosemia Marisel De Lucca 12. Glucose and connections with OLR1 and IL17A genes Burcu Bayoglu
Part 4. Other topics 13. Linking pathways and processes: retinoic acid and glucose Kazuhiro Kimura 14. Role of fructose in ischemia/reperfusion injury Gerald J. Maarman 15. ChREBP and cancer Katsumi Iizuka 16. Glucose Metabolism in CD4+ and CD8+ T Cells Clovis Steve Palmer 17. Correlation between sugar consumption and ectopic fat Nicola McKeown 18. Beneficial applications of glucosamine Khadijeh Jamialahmadi 19. Glycoprotein folding Julio Javier Caramelo 20. Sugars, Sweet Taste Receptors, and Brain Responses Chung Owyang 21. Master Role of Glucose-6 Phosphate in Cell Signalling and Consequences of its Deregulation in the Liver and Kidneys Fabienne Rajas 22. Effects of D-galactose on the ageing heart and brain Nipon Chattipakorn 23. Glucose Homeostasis and the gastrointestinal tract Simon Veedfald, Jens Juul Holst and Nicolai Jacob Wewer Albrechtsen
Vinood B. Patel, BSc, PhD, FRSC, is currently a Reader in Clinical Biochemistry at the University of Westminster and honorary fellow at King's College London (Diabetes and Nutritional Sciences Division and the Department of Nutrition and Dietetics). He presently directs studies on molecular and metabolic pathways involved in organ disease, particularly related to subcellular organelles and cell death. He directs research into the role of nutrients, antioxidants, phytochemicals, minerals, toxins and macronutrients. Other areas of interest are identifying new biomarkers that can be used for the diagnosis and prognosis of disease and understanding oxidative stress. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King's College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. Dr Patel is a nationally and internationally recognized liver researcher and was involved in several NIH-funded biomedical grants. Dr Patel has edited more than 20 biomedical books in the area of nutrition, health and disease and has published over 150 articles In 2014, he was elected as a Fellow to the prestigious Royal Society of Chemistry for bridging the academic and intellectual gap between chemistry and biological function.