Neonatal Neurology, Volume 162 in the Handbook of Clinical Neurology, series updates the reader on the latest advances in the study of neurological diseases diagnosed in the fetal and neonatal periods. With recent advances in magnetic resonance imaging, digital electroencephalography recording, and genetic testing and diagnosis, there is expanding awareness relating to early onset neurological conditions and how their early diagnosis can improve prediction of outcome and subsequent neurodevelopmental outcome. This new volume covers diagnosis and management of congenital conditions, including brain malformations, neuromuscular conditions and genetic epilepsies, as well as acquired injury related to peri-partum events, prematurity, critical illness and systemic diseases.
- Provides an in-depth understanding of the basic scientific research, translational research and clinical consensus across neonatal and fetal medicine
- Explores how early neurological diagnosis can improve prediction of outcome and how management can improve subsequent neurodevelopmental outcome
- Features chapters co-authored by two experts, combining expertise in both neonatal and fetal neurology
1. Fetal neurology: principles and practice with a life-course perspective 2. Fetal toxicology 3. The placenta 4. Fetal and neonatal neuro-imaging 5. Fetal and neonatal neurogenetics 6. Congenital and perinatal infections 7. Preterm brain injury (white matter) 8. Preterm brain injury: germinal matrix / intraventricular hemorrhage and post-hemorrhagic ventricular dilatation 9. Cerebellar hypoplasia of prematurity: causes and consequences 10. Neonatal encephalopathy and hypoxic-ischemic encephalopathy 11. Perinatal arterial ischemic stroke 12. Neonatal cerebral sinovenous thrombosis 13. Biomarkers of brain injury 14. Monitoring and management of brain hemodynamics and oxygenation 15. Neuroprotection of the preterm brain 16. Neurodevelopmental outcome of children with congenital heart disease 17. Seizure classification, etiology and management 18. Diagnosis of seizures and encephalopathy using conventional EEG and amplitude integrated EEG 19. Outcome in preterm infants with seizures 20. Genetics of neonatal onset epilepsies 21. Neonatal hypotonia and neuromuscular conditions 22. Inborn errors of metabolism 23. High risk rollow-up: Early intervention and rehabilitation 24. Understanding and addressing barriers to communication in the context of neonatal neurologic injury: Exploring the ouR-HOPE approach