- Provides a comprehensive introduction to omega-3 and omega-6 fatty acids in neurological health and directions for future research- Features novel focus on the adverse effects of omega-6 fatty acids on neurological function and the counterbalancing of dietary and tissue omega-6 - Illustrates the importance of omega-3 fatty acids in longevity and cognitive impairment- Features new chapters on early effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases - Discusses links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements
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A. Omega Fatty acids and Brain: An overview 1. Essentiality of Omega-3 Polyunsaturated Fatty Acids for Mammalian Brain Development: A Translational Perspective 2. Thinking in polyunsaturated fatty acids, phospholipids and the brain 3. The Impact of Omega-3 Fatty Acids on Quality of Life 4. The Balance Between n-6 and n-3 and its Relation to Executive Function 5. Arachidonic Acid, Docosahexaenoic Acid, and Ethanol
B. Omega fatty acids: Brain and neurological development 6. Prenatal n-3 long-chain polyunsaturated fatty acids and children's executive functions 7. Omega-3 and Omega-6 fatty acid metabolism: Modeling growth and disease using Caenorhabditis elegans 8. Fatty acids and the hippocampus 9. Energy metabolism of neural cells under the control of phospholipases A2 and docosahexaenoic acid 10. Omega-3 and Cognition in Children with Malnutrition 11. Neuroprotective effects of melatonin and omega-3 on the central nervous system exposed to electromagnetic fields in the pre- and postnatal periods 12. Maternal omega 3 status: effects of cross-fostering on offspring brain lipids and hippocampal neurogenesis 13. Linking omega-3 fatty acids and depression 14. Omega 3 Fatty Acids and the Cardiovascular System
C. Diet and Brain disease treatment and Prevention 15. Dietary Strategies and Supplements for the Prevention of Cognitive Decline and Alzheimer's disease 16. N-3 long chain PUFA-containing phospholipids and neuroprotection 17. Omega-3 Polyunsaturated Fatty Acid Supplementation as a Potential Protective Factor or Treatment for Neurodegenerative Diseases 18. Neurobiological meaning of Omega-3 Fatty Acids and their potential role in the treatment of schizophrenia 19. Neurodevelopmental and behavioral effects of variations in Omega-3 Polyunsaturated Fatty Acids levels in vulnerable populations
D. Nutrients and the Brain 20. Omega-3 fatty acids and cognitive behavior 21. Link between sugar intake and fatty acid metabolism in brain 22. N-3 and -6 fatty acids in fish: a focus on non-marine species 23. Aspartame Induced Neurodegeneration Versus Omega 3 Alleviation 24. DHA-enriched formulations as a promising strategy for the treatment of hypoxic/ischemic brain injury 25. Alpha-linolenic acid and dementia in epidemiological studies 26. DHA a Key Supplement For Neurologic Health- An Insight 27. Obesity, Cognitive Functioning, and Dementia: A Lifespan Perspective 28. Fatty acids and brain health 29. Epigenetic effects of omega-3 fatty acids on neurons and astrocytes during brain development and senescence
Ronald Ross Watson, PhD, is Professor of Health Promotion Sciences at the University of Arizona, Mel and Enid Zuckerman College of Public Health. Dr. Watson began his research in public health at the Harvard School of Public Health as a Fellow in 1971 doing field work on vaccines in Saudi Arabia. He has done clinical studies in Colombia, Iran, Egypt, Saudi Arabia and the United States which provides a broad international view of public health. He has served in the military reserve hospital for 17 years with extensive training in medical responses to disasters as the chief biochemistry officer of a general hospital, retiring as a Lt. Colonel. He is a distinguished member of several national and international nutrition, immunology, and cancer societies. Dr. Watson's career has involved studying many lifestyle aspects for their uses in health promotion. He has edited over 100 biomedical reference books and 450 papers and chapters. His teaching and research focuses on alcohol, tobacco, and drugs of abuse in heart function and disease in mouse models.
Preedy, Victor R.
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a staff member of the Faculty of Life Sciences and Medicine within King's College London. He is also a member of the Division of Diabetes and Nutritional Sciences (research) and the Department of Nutrition and Dietetics (teaching). Professor Preedy is also Director of the Genomics Centre of King's College London.
Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctorate (DSc), for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as a Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. Professor Preedy has carried out research when attached to Imperial College London, The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. Prof Preedy is a leading expert on the science of health and has a long standing interest in neurological disease and tissue pathology. He has lectured nationally and internationally. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.