Molecular Evolutionary Models in Drug Discovery

Table of Contents

1. Introduction2. Molecular Autopoiesis3. Natural products and molecular networks4. Symbiogenesis autopoietic5. Metabolomic autopoiesis6. Clinical outcome and autopoiesis7. Toxical autopoiesis8. Future Research and Applications

Authors

Juan Bueno Chief Scientific Officer, Research Center of Bioprospecting and Biotechnology for Biodiversity Foundation (BIOLABB). Dr. Bueno is currently the Chief Scientific Officer for the Research Center of Bioprospecting and Biotechnology for Biodiversity Foundation (BIOLABB). He has an MD from Caldas University, Manizales, Colombia (2001) and a Master degree in biomedical sciences from Antioquia University, Medell�n, Colombia (2008). He is an expert in the design and implementation of antimicrobial platforms for to evaluate natural products and synthesis drugs with the aim of optimize in vitro antimicrobial activity selection of new chemical entities for future anti-infective pharmaceuticals. He was a Fellow, COLCIENCIAS-Universidad de Caldas (2002), a Fellow of University of the United Nations in antifungal susceptibility testing, Instituto Nacional de Enfermedades Infecciosas, INEI.ANLIS, Buenos Aires, Argentina (2004), and a Fellow, International Visitor Leadership Program on "Public Health�, United States Department of State, Bureau of Educational and Cultural Affairs (2012). He has been awarded by the Colombian Dermatology Association for best research in dermatology (2006), the Enrique Nu�ez Olarte award for pharmacological research by the Colombian Pharmacology Association (2009). Author of 40 articles in pharmacological research. Author in seven chapter books in antimicrobial drug discovery.