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Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease

  • ID: 4829307
  • Book
  • 362 Pages
  • Elsevier Science and Technology
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Sialic Acids and Sialoglycoconjugates in the Biology of life, Health and Disease provides insight in the latest knowledge developed in the field of sialoglycobiology.

Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesised post translationally they play important role in recognition, signalling, immunological response and cell-cell interaction. Sialioglycoconjugates form an important biomarker in disease. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era sialoglybiology has become more and more important in deciphering a health and disease condition.

Sialic Acids and Sialoglycoconjugates in the Biology of life, Health and Disease enables the reader to understand the role of sialylation as post translational modification.

  • Discusses the sialic acid and their role in different diseases other than cancer
  • Provides understanding to sialylations as post translational modifications (PTM)
  • Demonstrates the impact sialylation has on infectious diseases, the autoimmune system and health
  • Gives insight in the importance of sialic acid biology through animal models
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1. Sialic acid and their conjugates and bio synthesis 2. Sialoglycoconjugates in plants 3. Sialic acid and their conjugates in invertebrate and vertebrate animals and their synthesis 4. Sialic acids and glyconjugates in humans and their synthesis 5. Sialoglycoconjugates and their role in human physiology 6. Sialic acid and its conjugates in human infectious diseases 7. Sialic acid and its conjugates in autoimmune disorders 8. Sialic acid storage disorders 9. Sialic acid and their conjugates as disease biomarkers 10. Sialic acids and its conjugates in cancer 11. Sialic acids and its conjugates in endocrinal disorders 12. Applications of nanotechnology to sialic acid biology for targeting of diseases

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Ghosh, Shyamasree
Dr. Shyamasree Ghosh has been working in the field of sialoglycoconjugates for more than 12 years now, since her PhD in the topic of Sialoglycocongugates in Childhood Acute Lymphoblastic Leukemia (ALL). The author has considerable experience and published quite a large number of publications in reputed international journals and is cited across the globe for her work. She is one of the well-known scientist in this field of sialoglycobiology. Currently working to the capacity of Scientific Officer (F), in the School of Biological sciences, National institute of Science Education and Research (NISER), Bhubaneswar and has authored large number of publications and books in reputed
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