Inflammation is a biological response triggered by different stimuli that has in the body a potentially damaging effect. In certain conditions, such as injury or infection, inflammation is a normal, healthy response. However, inflammatory disorders that result in the immune system attacking the body's own cells or tissues may cause abnormal inflammation, which results in chronic pain, redness, swelling, stiffness, and damage to normal tissues. Mechanisms involved in promoting a number of different inflammatory disorders and their targeting for therapeutic benefit have been one of the hottest topics in last few decades. The two consecutive volumes (119 and 120) dedicated to this subject cover a wide spectrum of inflammatory disorders, mechanisms that are believed to cause them and different strategies for managing the inflammatory diseases.
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Table of Contents
1. Using evasins to target the chemokine network in inflammation Shoumo Bhattacharya and Akane Kawamura 2. Biological functions and clinical implications of interleukin-34 in inflammatory diseases Yun Ge, Man Huang, Xiao-mei Zhu, and Yong-ming Yao 3. Pattern recognition receptors as potential drug targets in inflammatory disorders Declan P. McKernan 4. Glycosylation changes in inflammatory diseases Sophie Groux-Degroote, Sumeyye Cavdarli, Kenji Uchimura, Fabrice Allain, and Philippe Delannoy 5. Inflammatory bowel disease and targeted oral anti-TNFa therapy Owen R. Griffiths, John Landon, Ruth E. Coxon, Keith Morris, Philip James, and Rachel Adams 6. Interplay between inflammation and cancer Rekha Khandia and Ashok Munjal 7. Microglial NLRP3 inflammasome activation in multiple sclerosis Melis Olcum, Bora Tastan, Cagla Kiser, Sermin Genc and Kursad Genc 8. Sleep deprivation, oxidative stress and inflammation Fatin Atrooz and Samina Salim
