Pathology: Oxidative Stress and Dietary Antioxidants bridges the disciplinary knowledge gap to help advance medical sciences and provide preventative and treatment strategies for pathologists, health care workers, food scientists and nutritionists who have divergent skills. This is important as oxidative stress can be ameliorated with pharmacological, nutraceutical or natural agents. While pathologists and clinical workers understand the processes in disease, they are less conversant in the science of nutrition and dietetics. Conversely, nutritionists and dietitians are less conversant with the detailed clinical background and science of pathology. This book helps to fill those gaps.
- Saves clinicians and researchers time by helping them to quickly access the very latest details on a broad range of pathologies and oxidation issues
- Combines the science of oxidative stress and the putative therapeutic usage of natural antioxidants in the diet
- Includes preclinical, clinical and population studies to help pathologists, nutritionists, dieticians, and clinicians map out key areas for research and further clinical recommendations
Part 1 Oxidative Stress and Pathology
Updated based on reviewer feedback (authors not confirmed) 1. Free radicals: what they are and what they do (author this is an overview of the type of reactive species) 2. Connecting free radicals and MRI in pathology 3. Superoxide anions and their role in tissue pathologies 4. The clinical biochemistry of oxidative stress in pathological conditions (author this is on biomarkers in urine and blood) 5. Oxidative stress in the pathology of brain disease: a focus on Parkinson's disease 6. Oxidative stress in the pathology of skin disease 7. Oxidative stress in the pathology of kidney disease 8. Oxidative stress in the pathology of reproductive disorders: a focus on preeclampsia 9. Free radicals, oxidative stress and the pathology of liver disease 10. Oxidative stress in oral pathologies 11. Linking oxidative stress and cancer: a focus on prostate cancer (author to mention many cancers and then focus on one or two) 12. Oxidative stress and breast cancer 13. Oxidative stress and cardiovascular disease 14. Genomics and oxidative stress: Linking DNA methylation 15. Nutritional genomics, cardiovascular disease and oxidative stress
Part 2 Antioxidants and Pathology 16. Anthocyanins as antioxidants and use in bone pathology 17. Antioxidant Ruscus species and antioxidant use in tissue pathology 18. Antioxidant ziziphus jujuba and use in pathology 19. Ascorbic acid as an antioxidant and applications to the CNS 20. Castanea sativa species and antioxidant use in tissue pathology 21. Cinnamic acids and use as an antioxidant 22. Copaiba oil as an antioxidant and use in liver pathology 23. Coriandrum sativum as an antioxidant and cancer protection 24. Curcumin and related antioxidants and applications to tissue pathology 25. Dietary antioxidant capacity and the ultimate marker of pathology- mortality 26. Ellagic acid: sources and uses in the pathology of cancer 27. Epigallocatechin gallate (EGCG) as an antioxidant and use in pathology (this must be a new review not published before and coverage of many aspects of EGCG 28. Luteolin as an antioxidant and cellular pathology 29. Mediterranean diet: antioxidant components and uses in liver pathology 30. Methylsulfonylmethane as an antioxidant and use in pathology 31. Polyphenolic foods: applications as antioxidants to tissue pathology 32. Pomegranate extract as an antioxidant and use in pathological condition 33. Resveratrol as an antioxidant and use in pathological condition 34. Selenium: role in antioxidant status and use in inflammatory pathologies 35. Tocopherol usage, antioxidant effects and pathology of diabetes 36. Trace elements and antioxidant effects pediatric pathology 37. Vitamin C as an antioxidant and cardiovascular disease
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a staff member of the Faculty of Life Sciences and Medicine within King's College London. He is also a member of the Division of Diabetes and Nutritional Sciences (research) and the Department of Nutrition and Dietetics (teaching). Professor Preedy is also Director of the Genomics Centre of King's College London.
Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctorate (DSc), for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as a Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. Professor Preedy has carried out research when attached to Imperial College London, The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. Prof Preedy is a leading expert on the science of health and has a long standing interest in neurological disease and tissue pathology. He has lectured nationally and internationally. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.