Vibrational Spectroscopy Applications in Biomedical, Pharmaceutical and Food Sciences

Table of Contents

1. Introduction

Part 1. THEORETICAL ASPECTS OF VIBRATIONAL SPECTROSCOPY2. Molecular vibration3. Infrared absorption4. Raman scattering5. Surface-enhanced effect

Part 2. INSTRUMENTATION AND SAMPLING METHODS IN VIBRATIONAL SPECTROSCOPY ANALYSIS6. Sampling in Infrared spectroscopy7. Sampling in Raman Spectroscopy

Part 3. BIOMEDICAL ANALYSIS APPLICATIONS8. Body fluids analysis9. Tissues analysis10. Biomedical analysis11. Clinical diagnosis

Part 4. PHARMACEUTICAL ANALYSIS APPLICATIONS12. Drugs13. Polymorphic substances analysis

Part 5. FOOD ANALYSIS14. Fruit and vegetable analysis15. Solid and semisolid dairy product analysis16. Alcohol beverages analysis17. Conclusions

Authors

Andrei A. Bunaciu Senior Researcher AAB-IR Research Laboratory, Bucharest, Romania. Andrei A. Bunaciu, received his Ph.D. from Politehnica University of Bucharest, Faculty of Chemistry, Department of Analytical Chemistry in the field of ion-selective membrane electrodes applied in pharmaceutical analysis in 1990. After several years as Senior Researcher in the Institute of Chemical and Pharmaceutical Research and Romanian Intelligence Service, he became a Senior Researcher in the Vibrational Spectroscopy Department at SCIENT - Research Center for Instrumental Analysis, Bucharest. Now he is the owner of AAB_IR research company. His research interests concern molecular recognition of pharmaceutical and biological compounds using infrared and Raman spectroscopy techniques. He is the author/co-author of about 80 publications on various aspects of sensors, vibrational spectroscopy, and other instrumental techniques in medical and pharmaceutical analysis. Hassan Y. Aboul-Enein Professor Emeritus, Pharmaceutical and Medicinal Chemistry Department, National Research Center, Cairo, Egypt. Hassan Y. Aboul Enein is a Professor Emeritus at the National Research Center in Cairo, Egypt. He was head of the Pharmaceutical Analysis Laboratory at King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. He is an author of over 1100 refereed articles, 48 book chapters and 365 conference presentations. He also authored and edited 8 books. He is an Editorial Board Member of 22 journals, including Analytica Chimica Acta, Chirality, Biomedical Chromatography, Critical Reviews in Analytical Chemistry, Journal of Separation Science, Chromatographia, and Chirality. He is a member of the World Health Organization (WHO) advisory panel in International Pharmacopoeia and Pharmaceutical Preparations and a Fellow of the Royal Society of Chemistry (UK). He received his Ph.D. in 1971 in pharmaceutical and medicinal chemistry from the University of Mississippi, USA. He has received several awards, including the Scopus award for the most cited scientist in the Middle East in 2009. Vu Dang Hoang Associate Professor, Department of Analytical Chemistry and Toxicology, Hanoi University of Pharmacy, Hanoi, Vietnam. Vu Dang Hoang completed his doctorate in pharmaceutics at the University of Strathclyde, UK, in 2005 and conducted postdoctoral research at the Ecole Nationale d'Ing�nieurs des Techniques des Industries Agricoles et Alimentaires, France, in 2006. He has been lecturing at the Department of Analytical Chemistry and Toxicology, Hanoi University of Pharmacy, Vietnam, since 2007. He became an associate professor in the field of drug quality control in 2015. His research interests include chemico-physical characterization of topical drug delivery systems and chemometrics-based methods for the analysis of drugs in pharmaceutical dosage forms and biological fluids. So far, he has authored more than 30 publications in pharmaceutical research and analytical chemistry in leading national and international peer-reviewed journals.