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Neoantigen Targeted Therapies Market - Global Forecast 2025-2032

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    Report

  • 195 Pages
  • November 2025
  • Region: Global
  • 360iResearch™
  • ID: 4896728
UP TO OFF until Jan 01st 2026
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Neoantigen targeted therapies are rapidly redefining standards in precision oncology. Senior leaders across pharmaceuticals, biotech, and healthcare are exploring these personalized solutions to address the growing complexities of cancer treatment and market demand for tailored, value-driven patient care.

Market Snapshot: Growth Trajectory of Neoantigen Targeted Therapies

The Neoantigen Targeted Therapies Market is experiencing robust double-digit compound annual growth, driven by increased adoption of precision medicine, investment in novel immunotherapy pipelines, and expanding regulatory support for advanced oncology solutions. A marked acceleration in both research funding and commercial partnerships continues to fuel expansion across global regions and key application segments.

Scope & Segmentation: Comprehensive Coverage Across Modalities, Approaches, and Geographies

This research report offers an in-depth analysis of the neoantigen targeted therapies landscape, dissecting key market segments, technology deployments, and end-user dynamics. Covered segmentation includes:

  • Therapy Modalities: Adoptive cell therapies, notably CAR-T, T cell receptor (TCR), and tumor-infiltrating lymphocyte (TIL) treatments; personalized neoantigen vaccines based on dendritic cell platforms, DNA/RNA solutions, and synthetic long peptides.
  • Treatment Approaches: Combination therapies leveraging checkpoint inhibitors, chemotherapies, and targeted therapeutics; stand-alone monotherapy regimens.
  • Route of Administration: Multiple delivery methods such as oral administration and parenteral formats, including intramuscular, intravenous, and subcutaneous options.
  • Age Groups: Patient cohorts segmented into adult, geriatric, and pediatric populations.
  • Target Disease Indications: Major cancers such as bone, colorectal, gynecological, non-small cell lung, and renal cell carcinoma.
  • End Users: Academic and government research institutions, hospitals, clinics, and specialty healthcare centers.
  • Geographical Regions: The scope extends across North America (US, Canada, Mexico), Latin America, Europe, Middle East, Africa, and Asia-Pacific (including China, India, Japan, South Korea, and others).
  • Competitive Coverage: Detailed analysis of key company pipelines and strategies, such as those pursued by Achilles Therapeutics, BioNTech, AstraZeneca, Moderna, Gilead, Roche, and additional innovators and incumbents.

Key Takeaways for Senior Decision-Makers

  • Technology convergence, including next-generation sequencing and advanced bioinformatics, is accelerating the transition from research to clinical application in neoantigen targeted therapies.
  • Collaborative research models and strategic industry partnerships are enabling scalable manufacturing, shared clinical infrastructure, and early patient access programs.
  • Evolving regulatory attitudes and reimbursement frameworks are reducing traditional barriers, with agencies increasingly receptive to adaptive trial designs and real-world data submissions.
  • Supply chain resilience has become paramount in response to geopolitical shifts and tariff complexities, prompting closer supplier relationships and diversified manufacturing footprints.
  • Regional ecosystems play a critical role, with the Americas driving rapid commercial adoption, Europe advancing pan-regional approval networks, and Asia Pacific building integrated R&D and manufacturing capabilities.

Tariff Impact on Neoantigen Therapy Supply Chains

Recent changes in US tariff policy are affecting input costs across core components—such as reagents and laboratory equipment—and creating new logistics challenges for multi-center clinical trials. Market leaders are adapting by optimizing sourcing strategies, localizing manufacturing steps, and relying on contract development partners for risk mitigation and cost containment at each supply chain stage.

Methodology & Data Sources

This study integrates multi-tier primary and secondary research, with data from peer-reviewed literature, regulatory updates, clinical registries, market databases, and expert interviews. Rigorous validation processes and triangulation methods support segmentation accuracy. Scenario analyses and ongoing peer review underpin robust, actionable intelligence.

Why This Report Matters for Strategic Leadership

  • Provides targeted intelligence for investment, partnership, and R&D decisions relevant to the neoantigen targeted therapies market.
  • Enables senior executives to anticipate supply chain risks, regulatory shifts, and emerging technological trends in oncology personalization.
  • Delivers actionable recommendations on navigating complex global reimbursement and go-to-market pathways, from early development to broad clinical adoption.

Conclusion

Neoantigen targeted therapies are poised to reshape future cancer care strategies, with stakeholders across research and industry aligning on patient-centric outcomes. Effective integration of technology, partnership, and market insight will drive resilient growth and rapid innovation in this evolving sector.

 

Additional Product Information:

  • Purchase of this report includes 1 year online access with quarterly updates.
  • This report can be updated on request. Please contact our Customer Experience team using the Ask a Question widget on our website.

Table of Contents

1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders
2. Research Methodology
3. Executive Summary
4. Market Overview
5. Market Insights
5.1. Rising demand for personalized immunotherapies driving neoantigen innovation
5.2. Development of non-viral vector platforms for in vivo delivery of neoantigen-encoding mRNA therapies
5.3. Emergence of combination regimens pairing neoantigen vaccines with immune checkpoint blockade therapies
5.4. Advances in lipid nanoparticle delivery systems for mRNA-based neoantigen vaccines in oncology
5.5. Clinical translation of personalized neoantigen-specific T cell receptor therapies in advanced melanoma patients
5.6. Technological advances fueling growth in neoantigen-targeted therapy market
5.7. Advances in multi-epitope neoantigen delivery systems enhancing immune responses against solid tumors
5.8. Regulatory framework evolution guiding clinical development of individualized neoantigen immunotherapies
5.9. AI and genomics transforming neoantigen discovery and development
5.10. Implementation of digital twin simulations to predict patient-specific neoantigen immune engagement in silico
6. Cumulative Impact of United States Tariffs 2025
7. Cumulative Impact of Artificial Intelligence 2025
8. Neoantigen Targeted Therapies Market, by Therapy Modality
8.1. Adoptive Cell Therapy
8.1.1. CAR-T Cell Therapy
8.1.2. T Cell Receptor (TCR) Therapy
8.1.3. Tumor-infiltrating lymphocytes (TIL)
8.2. Personalized Neoantigen Vaccines
8.2.1. Dendritic Cell (DC) Vaccines
8.2.2. DNA/ RNA-based Vaccines
8.2.3. Peptide (SLP) Vaccines
9. Neoantigen Targeted Therapies Market, by Treatment Approach
9.1. Combination Therapy
9.2. Monotherapy
10. Neoantigen Targeted Therapies Market, by Route of Administration
10.1. Oral
10.2. Parenteral
10.2.1. Intramuscular
10.2.2. Intravenous
10.2.3. Subcutaneous
11. Neoantigen Targeted Therapies Market, by Age Group
11.1. Adult
11.2. Geriatric
11.3. Pediatric
12. Neoantigen Targeted Therapies Market, by Target Disease Indication
12.1. Bone Cancer
12.2. Colorectal Cancer
12.3. Gynecological Cancer
12.4. Non-Small Cell Lung Cancer
12.5. Renal Cell Carcinoma
13. Neoantigen Targeted Therapies Market, by End-User
13.1. Academic & Government Research Institutes
13.2. Hospitals & Clinics
13.3. Specialty Clinics
14. Neoantigen Targeted Therapies Market, by Region
14.1. Americas
14.1.1. North America
14.1.2. Latin America
14.2. Europe, Middle East & Africa
14.2.1. Europe
14.2.2. Middle East
14.2.3. Africa
14.3. Asia-Pacific
15. Neoantigen Targeted Therapies Market, by Group
15.1. ASEAN
15.2. GCC
15.3. European Union
15.4. BRICS
15.5. G7
15.6. NATO
16. Neoantigen Targeted Therapies Market, by Country
16.1. United States
16.2. Canada
16.3. Mexico
16.4. Brazil
16.5. United Kingdom
16.6. Germany
16.7. France
16.8. Russia
16.9. Italy
16.10. Spain
16.11. China
16.12. India
16.13. Japan
16.14. Australia
16.15. South Korea
17. Competitive Landscape
17.1. Market Share Analysis, 2024
17.2. FPNV Positioning Matrix, 2024
17.3. Competitive Analysis
17.3.1. Achilles Therapeutics Limited
17.3.2. Agenus Inc.
17.3.3. AstraZeneca plc
17.3.4. BioNTech SE
17.3.5. Bristol-Myers Squibb Company
17.3.6. CureVac N.V.
17.3.7. Eli Lilly and Company
17.3.8. EpiVax, Inc.
17.3.9. F. Hoffmann-La Roche AG
17.3.10. Genentech, Inc.
17.3.11. Genocea Biosciences, Inc.
17.3.12. Gilead Sciences, Inc.
17.3.13. GlaxoSmithKline plc
17.3.14. Gritstone bio, Inc.
17.3.15. Immatics N.V.
17.3.16. Immunomic Therapeutics, Inc.
17.3.17. IOVANCE Biotherapeutics, Inc.
17.3.18. Medigene AG
17.3.19. Merck & Co., Inc.
17.3.20. Moderna, Inc.
17.3.21. Neon Therapeutics, Inc.
17.3.22. Nykode Therapeutics
17.3.23. Pfizer Inc.
17.3.24. Precision Biologics
17.3.25. Valo Therapeutics Ltd

Companies Mentioned

The companies profiled in this Neoantigen Targeted Therapies market report include:
  • Achilles Therapeutics Limited
  • Agenus Inc.
  • AstraZeneca plc
  • BioNTech SE
  • Bristol‑Myers Squibb Company
  • CureVac N.V.
  • Eli Lilly and Company
  • EpiVax, Inc.
  • F. Hoffmann-La Roche AG
  • Genentech, Inc.
  • Genocea Biosciences, Inc.
  • Gilead Sciences, Inc.
  • GlaxoSmithKline plc
  • Gritstone bio, Inc.
  • Immatics N.V.
  • Immunomic Therapeutics, Inc.
  • IOVANCE Biotherapeutics, Inc.
  • Medigene AG
  • Merck & Co., Inc.
  • Moderna, Inc.
  • Neon Therapeutics, Inc.
  • Nykode Therapeutics
  • Pfizer Inc.
  • Precision Biologics
  • Valo Therapeutics Ltd

Table Information