The Bioarchaeology of Metabolic Bone Disease, Second Edition provides an updated, comprehensive and invaluable source of information combining both clinical and paleopathological manifestations and effects on these groups of diseases. The range of potential tools for investigating metabolic diseases of bone are far greater than for many other conditions, hence this edition will consider the gross, radiological, histological and surface features using microscopic examination (light microscopy and scanning electron microscopy), that can be used to investigate metabolic bone diseases. Diagnostic tables have been updated with the latest information, including new research on vitamin C and D deficiency, cardiovascular disease and diabetes.
This second edition continues to explore the paleopathological research, covering the light of clinical and epidemiological work relevant to better understand the extent of the co-morbidity of these conditions. This is a must-have resource that demonstrates the important role that the analysis of metabolic bone disease has within bioarcheology for improving our understanding of health and life in past populations.
- Presents a clear introduction to bone biology relevant to each disease process
- Highlights key issues and ideas to provoke critical analysis across the spectrum of disciplines in physical anthropology, paleopathology, medical history and forensic anthropology
- Contains clear and user-friendly instructions for macroscopic, radiological and histological diagnoses
- Reviews current challenges in bioarcheology and provides direction for future research
1. Introduction to the study of Metabolic Bone Disease 2. The Study of Metabolic Disease in Bioarchaeology 3. Biology and Metabolism of Mineralised Tissues 4. Vitamin C Deficiency, Scurvy 5. Vitamin D Deficiency, Rickets and Osteomalacia 6. Age-related bone loss and Osteoporosis 7. Secondary Osteoporosis 8. Paget's Disease of Bone 9. Anaemia 10. Disease Co-Occurence 11. Overview and Future Directions for Research
Megan B. Brickley is currently Professor and Tier 1 Canada Research Chair in the Bioarchaeology of Human Disease at the Department of Anthropology, McMaster University, Canada. Her primary research interests are use of paleopathology in bioarchaeology, and interdisciplinary research on past human health and disease. She has served as past-Chair of the British Association of Biological Anthropology and Osteoarchaeology and an Associate Editor of American Journal of Physical Anthropology. Currently she is an Associate Editor of the International Journal of Paleopathology and the President Elect of the Paleopathology Association. Her publications include two co-authored and six edited books and eighty journal papers and book chapters.
Dr Rachel Ives is the Curator of Anthropology in the department of Earth Sciences at the Natural History Museum, London. She is responsible for the curation of the palaeoanthropology, fossil primate, human remains, and artefact collections and promotes scientific research, exhibitions, and outreach access to the collections. Rachel's research interests are in bone cell biology together with skeletal palaeopathology, particularly the metabolic bone diseases and disease co-occurrence. Rachel has carried out large-scale surveys of metabolic bone diseases in urban contexts and was a post-doctoral researcher on a Calleva Foundation funded Child Health project at the NHM, investigating how the skeleton changes during childhood growth and in response to pathology. Rachel previously worked in the commercial sector carrying out archaeological cemetery excavations and osteological analyses, and she continues work in osteoarchaeological consultancy for heritage development projects.
Simon completed his PhD in archaeology in 1987, and then spent a year teaching archaeology to schoolchildren. He then took up a job as Human Skeletal Biologist for Historic England, a post he still holds. This involves promulgating advice and standards for treatment of human remains from archaeological sites in England. His research interests span most areas of osteoarchaeology, and he has over 250 scientific publications. He helped found the British Association of Biological Anthropology and Osteoarchaeology, and the Society for the Study of Childhood in the Past. He is also a visiting member of staff in archaeology at the University of Southampton and at the University of Edinburgh.