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Nanoengineering in Musculoskeletal Regeneration

  • ID: 4991123
  • Book
  • August 2020
  • Region: Global
  • 220 Pages
  • Elsevier Science and Technology
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Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. Musculoskeletal degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation.

Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of therapeutic pipeline from biomedical discovery to clinical implementation, improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus and bone. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in the musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues.

  • A multidisciplinary book providing broad coverage in all research areas focused on the applications of nanotechnology in musculoskeletal regeneration
  • Useful for physician-scientists with the expertise of orthopedy and regenerative medicine, bioengineers or materials engineers with the expertise of biomaterials and nanoengineering, stem cell biologists, and chemists
  • A reference for many disciplines, including: bioengineering, biomaterials, tissue engineering, regenerative medicine, musculoskeletal regenerative medicine and nanomedicine
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1. Challenges toward Musculoskeletal Injuries and Diseases 2. Nanobiomaterials for Musculoskeletal Regeneration 3. Drug Delivery Nanosystems for Musculoskeletal Regeneration 4. Nanotechnology in Gene Therapy for Musculoskeletal Regeneration 5. Nanofabrication technology for Musculoskeletal Regeneration 6. Nanoengineering of Stem Cells for Musculoskeletal Regeneration 7. Nanotoxicity and Regulatory Aspects in Musculoskeletal Regeneration 8. Musculoskeletal Regenerative Nanomedicine: Current Therapies, Translational Hurdles and Future Directions

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Razavi, Mehdi
Dr. Mehdi Razavi is Assistant Professor of Medicine, Materials Science and Engineering, and BiionixTM (Bionic Materials, Implants & Interfaces) Cluster at University of Central Florida (UCF) since September 2019. Prior to his current appointment, he was a Postdoctoral Research Fellow in Regenerative Medicine with the Interventional Regenerative Medicine and Imaging Laboratory at Stanford University School of Medicine from September 2016 to September 2019. Before that he was a Postdoctoral Research Fellow in Biomaterials with the Brunel Centre for Advanced Solidification Technology (BCAST) in Institute of Materials and Manufacturing and Brunel Institute for Bioengineering (BIB) at Brunel University London from May 2015 to August 2016. He was also a Research Scholar in Biomaterials and Tissue Engineering with the School of Materials Science and Engineering, Helmerich Advanced Technology Research Center (HRC), at Oklahoma State University from July 2013 to April 2014 and an Adjunct Faculty with the Dental Materials Research Center, at Isfahan University of Medical Sciences from September 2014. He holds a PhD in Biomaterials from Isfahan University of Technology, awarded in August 2014, MSc in Materials Engineering from Isfahan University of Technology, awarded in February 2011 and a BSc in Materials Engineering from Isfahan University of Technology, awarded in September 2008. As his research honors, Isfahan University of Technology awarded him "The Best PhD Thesis”; and in June 2019, Stanford University awarded him "Poster Winner” of the 100+ posters presented at Bio-X. His research interests are mainly on Biomaterials, Nanomedicine, Tissue Engineering and Regenerative Medicine, Stem Cells, Orthopedic Implants and Bone scaffolds, Drug/Gene Delivery Systems, Ultrasound Therapy, Cancer Nanotechnology, and Pancreatic Islet Transplantation. His work has resulted in the publication of over 62 peer-reviewed journal articles, 16 book chapters, 5 books, 5 patents pending or granted, and 24 conference proceedings/talks, of which 69 have been as a first author and 57 as a corresponding author. His publications have been cited for over 1540 times, with an h-index of 25, and i-10 index of 37. He also serves as the chief editor, a member of editorial boards and a scientific reviewer for over 128 different journals, conferences, books, grants and dissertations.
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