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Diagnosis and Management in Parkinson's Disease

  • ID: 5007874
  • Book
  • August 2020
  • 816 Pages
  • Elsevier Science and Technology
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Diagnosis and Management in Parkinson's Disease: The Neuroscience of Parkinson's, Volume 1 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything concerning the neurology and neuroscience related to Parkinson's disease, from chemicals and cells to individuals. The book is an invaluable resource for neuroscientists, neurologists, and anyone in the field.
  • Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease
  • Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction
  • Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding
  • Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations
  • Serves as a "one-stop" source for everything you need to know about Parkinson's disease
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Section 1: Parkinson's Disease: Introductory Chapters 1. A Short History of Parkinson's Disease
from early 19th century and afterwards
an overview 2. Living with Parkinson's disease
from financial to emotional 3. The epidemiology of Parkinson's disease
an overview 4. Clinical Features of Parkinson's disease
an overview 5. The natural history of Parkinson's disease
an overview 6. The prognosis of Parkinson's disease
an overview 7. The neurobiology of Parkinson's disease
an overview 8. The pathophysiology of Parkinson's disease
an overview 9. Molecular and cellular mechanisms associated with Parkinson's disease
synuclein, amyloid protein, oligomers and beyond 10. Quality of life in Parkinson's disease 11. Gait in untreated Parkinson's disease 12. Levodopa-induced dyskinesias 13. Tremor in Parkinson's disease 14 The impact of Parkinson's disease on the family and careers

Section 2: Biomarkers and Diagnosis 15. Tissue biopsies as biomarkers in Parkinson's disease 16. Spinal fluid for biomarker discovery in Parkinson's disease 17. Clinical biomarkers in prodromal Parkinson's disease 18. The diagnosis of Parkinson's disease 19. Proteomics in Parkinson's disease 20. MicroRNAs as biomarkers in Parkinson's diseases 21. Phenotyping in Parkinson's disease 22. Diagnosis of speech disorders in Parkinson's disease 23. Identifying dementia in Parkinson's disease 24. Diagnosis of sleep disturbances in Parkinson's disease 25. Diagnosis of Parkinson's disease using magnetic resonance imaging 26. Use of ultrasound as a diagnostic tool in Parkinson's disease 27. Use of single-photon emission computerized tomography (SPECT) as a diagnostic tool in Parkinson's disease 28. Use of positron emission tomography (PET) as a diagnostic tool in Parkinson's disease

Section 3: Pharmacological Treatments for Parkinson's Disease 29. Dopamine Agonists and Parkinson's disease
an overview 30. Management with Levodopa in Parkinson's disease 31. Management with ripinirole in Parkinson's disease 32. Management with pramipexole in Parkinson's disease 33. Management with rotigotine in Parkinson's disease 34. Management with apomorphine in Parkinson's disease 35. Management with MAO-B Inhibitors in Parkinson's disease 36. Management with COMT inhibitors in Parkinson's disease 37. Management with anticholinergics in Parkinson's disease 38. Management with amantadine in Parkinson's disease

Section 4: Novel and Non-Pharmacological Therapies For Parkinson's Disease 39. Treatment with chelator in Parkinson's disease 40. Treatment with deep brain stimulation in Parkinson's disease 41. Olive leaf extract usage as an antioxidant and applications to Parkinson's disease 42. Treatment with Vitamin D for Parkinson's disease 43. Chemogenetics and applications for Parkinson's disease 44. Flavonoids and naringin usage in Parkinson's disease 45. Stem cells and applications to Parkinson's disease 46. Treatment with cannabis for Parkinson's disease 47. Treating sleep problems in Parkinson's disease 48. Perioperative treatments of Parkinson's disease 49. Exercise and Parkinson's disease 50. Molecular aspects: CB2 receptors and neuroprotection in Parkinson's disease
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Martin, Colin R.
Dr. Martin is a Professor of Mental Health at Buckinghamshire New University. He is a Registered Nurse, Chartered Health Psychologist, and a Chartered Scientist. He has published or has in press well over 250 research papers and book chapters. He is a keen book author and editor having written and/or edited several books all of which reflect his diverse academic and clinical interests that examine in-depth, the interface between mental health and physical health. These outputs include the Handbook of Behavior; Food and Nutrition (2011), Perinatal Mental Health: A Clinical Guide (2012); Nanomedicine and the Nervous System (2012), and the major reference works Comprehensive Guide to Autism (2014), Diet and Nutrition in Dementia and Cognitive Decline (2015), Comprehensive Guide to Post-Traumatic Stress Disorder (2016) and Metabolism and Pathophysiology of Bariatric Surgery: Nutrition, Procedures, Outcomes, and Adverse Effects (2017).
Preedy, Victor R.
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a staff member of the Faculty of Life Sciences and Medicine within King's College London. He is also a member of the Division of Diabetes and Nutritional Sciences (research) and the Department of Nutrition and Dietetics (teaching). Professor Preedy is also Director of the Genomics Centre of King's College London.

Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctorate (DSc), for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as a Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. Professor Preedy has carried out research when attached to Imperial College London, The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. Prof Preedy is a leading expert on the science of health and has a long standing interest in neurological disease and tissue pathology. He has lectured nationally and internationally. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.
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