- Offers comprehensive coverage of a broad range of topics related to dementia
- Serves as a foundational collection for neuroscientists and neurologists on the biology of dementia and brain dysfunction
- Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding
- Provides unique sections on specific subareas, intellectual components, and knowledge-based niches that will help readers navigate key areas for research and further clinical recommendations
- Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations
- Serves as a "one-stop" source for everything you need to know about dementia
Section 1 Dementia: Introductory Chapters 1. A review of the different types of dementia 2. The classification of dementia: problems and challenges 3. Alzheimer's disease: an overview 4. Dementia and competing hypothesis
the example of Alzheimer's disease and its various hypotheses 5. Lewy body dementia
an overview 6. Mixed dementia
an overview 7. Vascular dementia
an overview 8. Linking in physical activity and dementia 9. Risk factors in dementia 10. Mortality in dementia
linking in delirium 11. Rare forms of dementia 12. Prion diseases and dementia 13. Dementia in Parkinson disease 14. Dementia in traumatic brain injury 15. Risk factors in dementia
towards a coherent theory of dementia 16. Genetics of dementia
Section 2 Biomarkers, Psychometric Instruments, and Diagnosis 17. Circulating biomarkers in neurodegenerative dementias
YKL-40 and beyond 18. Salivary biomarkers in Alzheimer's disease 19. Use of cerebrospinal fluid in diagnosis of dementias 20. SPECT perfusion imaging in assessment of neurodegenerative dementias 21. Computerised tomography (CT) in assessment of neurodegenerative dementias 22. Magnetic resonance imaging (MRI) in assessment of neurodegenerative dementias 23. Questionnaires: The mini-mental state examination (MMSE) and beyond 24. The Cambridge Mental Disorders of the Elderly Examination (CAMDEX) and applications to dementia 25. The Montreal Cognitive Assessment (MoCA) and applications to dementia 26. The Hopkins Verbal Learning Test (HVLT) and applications to dementia 27. The Addenbrooke's Cognitive Examination (ACE) and applications to dementia 28. ALBA Screening Instrument (ASI) and applications to dementia 29. The prediction of Alzheimer's disease
Section 3 Pharmacological Treatments for Dementia 30. Cholinesterase inhibitors in dementias
an overview 31. NMDA receptor antagonists in dementia
an overview 32. Donepezil usage
a focused review 33. Rivastigmine usage
a focused review 34. Galantamine usage
a focused review 35. Memantine
a focused review 36. Failures and successes of monoclonal antibodies
bapineuzumab and beyond 37. Immunotherapies: an overview
Section 4 Non-Pharmacological Treatments 38. Internet counselling 39. Counselling in dementia 40. Cognitive rehabilitation in dementia 41. Cognitive stimulation in dementia 42. Anodal Transcranial Direct Current Stimulation 43. Nanoparticles: nanodiamond treatment in Alzheimer's disease 44. Increasing intakes and improving nutritional status in dementia 45. All-trans retinoic acid in Alzheimer's disease 46. Environmental enrichment in dementia 47. Music therapy in dementia 48. Aromatherapy in dementia 49. Massage in dementia 50. Dancing in dementia 51. Multisensory Stimulation in Dementia 52. Animal-assisted therapy in dementia 53. Occupational therapy in dementia
Dr. Martin is a Professor of Mental Health at Buckinghamshire New University. He is a Registered Nurse, Chartered Health Psychologist, and a Chartered Scientist. He has published or has in press well over 250 research papers and book chapters. He is a keen book author and editor having written and/or edited several books all of which reflect his diverse academic and clinical interests that examine in-depth, the interface between mental health and physical health. These outputs include the Handbook of Behavior; Food and Nutrition (2011), Perinatal Mental Health: A Clinical Guide (2012); Nanomedicine and the Nervous System (2012), and the major reference works Comprehensive Guide to Autism (2014), Diet and Nutrition in Dementia and Cognitive Decline (2015), Comprehensive Guide to Post-Traumatic Stress Disorder (2016) and Metabolism and Pathophysiology of Bariatric Surgery: Nutrition, Procedures, Outcomes, and Adverse Effects (2017).
Preedy, Victor R.
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a staff member of the Faculty of Life Sciences and Medicine within King's College London. He is also a member of the Division of Diabetes and Nutritional Sciences (research) and the Department of Nutrition and Dietetics (teaching). Professor Preedy is also Director of the Genomics Centre of King's College London.
Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctorate (DSc), for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as a Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. Professor Preedy has carried out research when attached to Imperial College London, The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. Prof Preedy is a leading expert on the science of health and has a long standing interest in neurological disease and tissue pathology. He has lectured nationally and internationally. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.