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Evolutionary Diversity as a Source for Anticancer Molecules

  • ID: 5007938
  • Book
  • September 2020
  • Region: Global
  • 400 Pages
  • Elsevier Science and Technology
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Evolutionary Diversity as A Source for Anticancer Molecules discusses evolutionary diversity as source for anticancer agents derived from bacteria, algae, bryophytes, pteridophytes and gymnosperms. The chapters have been designed to thoroughly describe their isolation and screening process by using relevant technology to develop anticancer drugs; they also discuss the role of nutraceuticals and natural products from invertebrates in cancer treatment.

This book presents a comprehensive approach of evolutionary diversities in natural products starting from the evolutionary mechanism, basic isolation, enumeration, and identification procedures to develop as anticancer agents. It also deals with some of the current challenges in prevention, and treatment of cancer against side effects of conventional drugs along with advanced therapeutic approaches by using natural products.

This book is a valuable source for cancer researchers, oncologists, biotechnologists, pharmacologists and several members of biomedical field interested in understanding more about natural products with anticancer potential.

  • Discusses the application of natural products in place of conventional drugs to minimize the side effects in cancer treatment
  • Explains the relation between evolutionary mechanism and climate change for production of secondary metabolites
  • Encompasses information on the preventive role of natural products against cancer
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1. Evolutionary mechanism for biosynthesis of diverse molecules
2. Effect of climate change in production of secondary metabolites
3. Isolation and characterization of bioactive compounds from natural resources: Metabolomics and Molecular approaches
4. Single-celled bacteria as tool for cancer therapy
5. Metabolic pathways of cyanobacteria for production of anticancer compounds
6. Prophyletic origin of algae as potential repository of anticancer compounds
7. Metabolic versatility of fungi as a source for anticancer compounds
8. Structural information of natural product metabolism in bryophytes
9. Landscape of natural product diversity in land-plants as source for anticancer molecules
10. Natural product from marine invertebrates
11. Antioxidative and antiproliferative properties of some common spices
12. Significance of Nutraceuticals in Cancer Therapy
13. Common techniques and methods for screening of natural products for developing of anticancer drugs
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Srivastava, Akhileshwar Kumar
Dr. Akhileshwar Kumar Srivastava works as Research Associate in Department of Botany, Banaras Hindu University. In his eight years of research, he published more than 16 research articles and book chapters in international and national journals of repute. His research specialization is primarily in area of pharmacognosy with genetics, metabolomics, bioinformatics, and molecular biology associated targeting cancer diseases. In addition, he has studied at Augusta University (formerly, Georgia Regents University) in Augusta, GA, USA on a J-1 Exchange Scholar Visa and at Ben-Gurion University, Israel.
Kannaujiya, Vinod Kumar
Dr. Vinod Kumar Kannaujiya is Assistant Professor in Department of Botany, MMV, Banaras Hindu University. He received MSc and PhD degree in Botany from Centre of Advanced Study in Botany, Banaras Hindu University. He has been working on the ultraviolet stress response of cyanobacteria including value added enzymes, proteins, pigments and natural compounds. He has been awarded with prestigious fellowships from Council of Scientific and Industrial Research, New Delhi, India. He has also been awarded Dr. D.S. Kothari Post-Doctoral Fellowship from University Grant Commission, New Delhi, India. He is a recipient of UGC-Startup project grant from UGC, New Delhi, India. He is life member fellow of Indian Photobiology Society. Dr. Kannaujiya has published over 40 original research papers, reviews, and book chapters.
Singh, Rajesh Kumar
Dr. Rajesh Kumar Singh is currently working as research associate in Centre of Experimental Medicine & Surgery at Banaras Hindu University. His research focus is pharmacognosy, reverse pharmacology, drug design and discovery, extraction & isolation of natural products, cell culture, and handling of different rodents. He has published several research articles in reputed journals during his research work. At present, he is involved in developing Indian origin cell line and screening of drugs of natural origin for the treatment of gallbladder cancer.
Singh, Divya
Dr. Divya Singh is presently working as research associate in Department of Chemical Engineering, IIT, Banaras Hindu University. Her research specialization is primarily in genetics, proteomics, metabolomics, toxicology, bioinformatics and molecular biological evaluation in various in vivo and in vitro plant models to elucidate the physiological changes and evaluate the DNA damage potency.
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