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CAR T Cell Therapy Market Global Forecast by Regions, Targeted Antigens, Clinical Trials/Study, Companies

  • ID: 5115518
  • Report
  • June 2020
  • Region: Global
  • 167 pages
  • Renub Research

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FEATURED COMPANIES

For many years, the support of cancer therapy was chemotherapy, surgery and radiation therapy. However, in recent times, CAR-T cell therapy has been introduced as an incredibly supportive treatment for cancer patients. Since the introduction of chemotherapy, this treatment is one of the most significant breakthroughs. In this therapy, immune cells are collected from patients, and it is modified in the laboratory by doctors. After modification, these immune cells are infused back into the patient as they can easily recognize and kill cancer cells. These infused cells get multiplied and stay in the body as “living drugs.” According to analysis, CAR-T Cell Therapy Market is expected to be USD 7.4 Billion by the end of the year 2028.

Growth Factors for CAR-T Cell Therapy

Factors such as growing numbers of cancer in adults and children, and increasing policy initiatives to encourage cell therapy research in cancer, and increasing numbers of clinical trials worldwide are some of the main drivers for the global demand for CAR T cell therapy. The economic scenario in the CAR-T cell therapy industry is very dynamic, and key players compete with each other to gain access to major markets in the United States and Europe. Companies are seeking to secure treatment facilities to increase access for patients to their treatments.

Developments did by Companies in CAR T Cell Therapy

In 2017, a new milestone was set for oncology patients when the FDA approved the first two CD19-targeted known as (Chimeric Antigen Receptor) CAR T cell therapies produced by Novartis and Gilead Sciences known as Kite Pharma in the United States. Such two approvals have helped to improve the global demand for CAR T cell therapy because more companies are searching for this excellent opportunity to reach the marketplace. More than 200 CAR T clinical trials are ongoing or completed in various parts of the world. In 2018, Novartis announced its 33 approved centres in the U.S. and Gilead announced its 28 approved centres for the care of patients. Companies are also coming up with new developments in the field.

Celgene, a global company, is expected to file for approval in USFDA of bb2121 (idecabtagene vicleucel) in myeloma during the first half of 2020 and lisocabtagene maraleucel in lymphoma in the fourth quarter of 2020.

This latest study report “CAR T Cell Therapy Market Global Forecast by Regions (North America, Europe, Asia Pacific, Latin America, Middle East, Africa), Targeted Antigens (CD19, CD20, GD2, CD22, CD30, CD33, HER2, MESO, EGFRvII, Others), Clinical Trials/Study (CD19, CD20, GD2, CD22, CD30, CD33, HER1, HER2, MESO, EGFRvII), Companies (Novartis, Gilead Sciences (Kite Pharma), Celgene Corporation (Juno Therapeutics), Celyad)” provides a detailed and comprehensive insight of the global CAR T cell therapy market.

By Antigens - Based on antigens, CAR T Cell Therapy Market is further Segmented into 10 Segments

1. CD19
2. CD20
3. GD2
4. CD22
5. CD30
6. CD33
7. HER2
8. MESO
9. EGFRvII
10. Others

By Region - 6 Regions CAR T Cell Market is studied in this report

1. North America
2. Europe
3. Asia Pacific
4. Latin America
5. Middle East
6. Africa

All the companies have been studied from three points
  • Overview
  • Initiatives & Recent Developments
  • Revenue
Key Companies covered in this report are
  • Novartis
  • Gilead Sciences (Kite Pharma)
  • Celgene Corporation (Juno Therapeutics)
  • Celyad
Global - CAR T Cell Therapy Clinical Trials/Study
1. CD19
2. CD20
3. GD2
4. CD22
5. CD30
6. CD33
7. HER1
8. HER2
9. MESO
10. EGFRvII

China CAR T Cells Clinical Trials Details
  • By Cities CAR T Cells Clinical Trials
  • CD19 Directed CAR T Cells Clinical Trials
  • Non-CD19 Directed CAR T Cells Clinical Trials
  • Solid Tumors CAR T Cells Clinical Trials
Regulation of CAR T Cell Therapy in 3 Regions is covered in the report
  • United States
  • European Union
  • China
IPO/Investment/Funding/Partnership in CAR T Cell Therapy Market
  • Venture Capital Investment
  • Initial Public Offerings
  • Strategic Partnerships/Deals
  • Key CAR T Technology Deals
Note: Product cover images may vary from those shown

FEATURED COMPANIES

1. Executive Summary

2. Global Chimeric Antigen Receptor (CAR)-T cell Therapy Market

3. Market Share - CAR-T Cell Therapy
3.1 By Geographical Region
3.2 By Targeted Antigens

4. Targeted Antigen Market
4.1 CD19
4.1.1 Introduction
4.1.2 Market Size and Forecast
4.2 CD20
4.2.1 Introduction
4.2.2 Market Size and Forecast
4.3 GD2
4.3.1 Introduction
4.3.2 Market Size and Forecast
4.4 CD22
4.4.1 Introduction
4.4.2 Market Size and Forecast
4.5 CD30
4.5.1 Introduction
4.5.2 Market Size and Forecast
4.6 CD33
4.6.1 Introduction
4.6.2 Market Size and Forecast
4.7 HER2
4.7.1 Introduction
4.7.2 Market Size and Forecast
4.8 Mesothelin (MESO)
4.8.1 Introduction
4.8.2 Market Size and Forecast
4.9 EGFRvIII
4.9.1 Introduction
4.9.2 Market Size and Forecast
4.10 Others
4.10.1 Market Size and Forecast

5. Geographical CAR-T Cell Therapy Market (2016 -2026)
5.1 North America
5.2 Europe
5.3 Asia Pacific
5.4 Latin America
5.5 Middle East
5.6 Africa

6. Global - CAR-T Cell Clinical Trials/Study
6.1 CD19
6.2 CD20
6.3 CD22
6.4 CD30
6.5 CD33
6.6 EGFRvIII
6.7 GD2
6.8 HER1
6.9 HER2
6.10 MESO

7. China CAR-T Cells Clinical Trials Details
7.1 By Cities CAR-T Cells Clinical Trials
7.2 CD19 Directed CAR-T Cells Clinical Trials
7.3 Non-CD19 Directed CAR-T Cells Clinical Trials
7.4 Solid Tumors CAR-T Cells Clinical Trials

8. CAR-T Cell Therapy SWOT Analysis
8.1 Strength
8.2 Weakness
8.3 Opportunities
8.4 Threats

9. Regulation in CAR-T Cell Therapy
9.1 United States
9.2 European Union
9.3 China

10. IPO/Investment/Funding/Partnership in CAR-T Cell Therapy Market
10.1 Venture Capital Investment
10.2 Initial Public Offerings of CAR-T Companies
10.3 CAR-T Companies Strategic Partnerships/Deals
10.4 Key CAR-T Technology Deals

11. Growth Drivers
11.1 FDA Approvals of CAR-T Therapy
11.2 Dramatically Increasing Number of CAR-T Cell Trials Globally

12. Challenges
12.1 Regulatory Challenges
12.2 Very Expensive CAR-T Therapy Treatment

13. Novartis
13.1 Company Overview
13.2 Initiatives
13.2.1 Point 1
13.2.2 Point 2 Kymriah® (tisagenlecleucel), First-in-class CAR-T Therapy from Novartis Received Second FDA Approval
13.2.3 Point 2
13.3 Financial Insight

14. Gilead Sciences (Kite Pharma)
14.1 Company Overview
14.2 Company Initiatives
14.2.1 Point 1
14.2.2 Point 2
14.3 Company Financial Insight

15. Celgene Corporation (Juno Therapeutics)
15.1 Company Overview
15.2 Company Initiatives
15.2.1 Point 1
15.2.2 Point 2
15.3 Company Financial Insight

16. Celyad
16.1 Company Overview
16.2 Company Initiatives
16.2.1 Point 1
16.2.2 Point 2
16.2.3 Point 3
16.3 Financial Insight

List of Figures:
Figure 2-1: Global - CAR-T Cell Therapy Market (Million US$), 2017 - 2019
Figure 2-2: Global - Forecast for CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 3-1: Global - CAR-T Cell Therapy Regional Market Share (Percent), 2017 - 2019
Figure 3-2: Global - Forecast for CAR-T Cell Therapy Regional Market Share (Percent), 2020 - 2028
Figure 4-1: Global - CD19 Antigen CAR-T Cell Therapy Market (Million US$), 2017 - 2019
Figure 4-2: Global - CD19 Antigen CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 4-3: Global - Forecast for CD20 Antigen CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 4-4: Global - Forecast for GD2 Antigen CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 4-5: Global - Forecast for CD22 Antigen CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 4-6: Global - Forecast for CD30 Antigen CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 4-7: Global - Forecast for CD33 Antigen CAR-T Cell Therapy Market (Million US$), 2017 - 2028
Figure 4-8: Global - Forecast for HER2 Antigen CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 4-9: Global - Forecast for MESO Antigen CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 4-10: Global - Forecast for EGFRvIII Antigen CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 4-11: Global - Forecast for Others Antigen CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 5-1: North America - CAR-T Cell Therapy Market (Million US$), 2017 - 2019
Figure 5-2: North America - Forecast for CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 5-3: Europe - CAR-T Cell Therapy Market (Million US$), 2017 - 2019
Figure 5-4: Europe - Forecast for CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 5-5: Asia Pacific - CAR-T Cell Therapy Market (Million US$), 2017 - 2019
Figure 5-6: Asia Pacific - Forecast for CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 5-7: Latin America - CAR-T Cell Therapy Market (Million US$), 2017 - 2019
Figure 5-8: Latin America - Forecast for CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 5-9: Middle East - CAR-T Cell Therapy Market (Million US$), 2017 - 2019
Figure 5-10: Middle East - Forecast for CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 5-11: Africa - CAR-T Cell Therapy Market (Million US$), 2017 - 2019
Figure 5-12: Africa - Forecast for CAR-T Cell Therapy Market (Million US$), 2020 - 2028
Figure 7-1: China - By Cities CAR-T Cells Clinical Trials (Number), 2017
Figure 11-1: Global - CAR-T New & Total Clinical Trials (Number), 2012-2017
Figure 11-2: Global - By Phase CAR-T Clinical Trials (Number), 2017
Figure 13-1: Novartis - Global Sales (Million US$), 2015 - 2019
Figure 13-2: Novartis - Forecast for Global Sales (Million US$), 2020 - 2028
Figure 14-1: Gilead Sciences - Global Sales (Million US$), 2017 - 2019
Figure 14-2: Gilead Sciences - Forecast for Global Sales (Million US$), 2020 - 2028
Figure 15-1: Celgene - Global Sales (Million US$), 2013 - 2019
Figure 15-2: Celgene - Forecast for Global Sales (Million US$), 2020 - 2028
Figure 16-1: Celyad - Global Sales (Million US$), 2013 - 2019
Figure 16-2: Celyad - Forecast for Global Sales (Million US$), 2020 - 2028

List of Tables
Table 3 1: Global - Current & Forecast for CAR-T Cell Therapy Targeted Antigens Market Share (Percent), 2017 - 2028
Table 6 1: Global - Details of CD19 CAR-T Studies, 2018
Table 6 2: Global - Details of CD20 CAR-T Studies, 2018
Table 6 3: Global - Details of CD22 CAR-T Studies, 2018
Table 6 4: Global - Details of CD30 CAR-T Studies, 2018
Table 6 5: Global - Details of CD33 CAR-T Studies, 2018
Table 6 6: Global - Details of EGFRvIII CAR-T Studies, 2018
Table 6 7: Global - Details of GD2 CAR-T Studies, 2018
Table 6 8: Global - Details of HER1 CAR-T Studies, 2018
Table 6 9: Global - Details of HER2 CAR-T Studies, 2018
Table 6 10: Global - Details of MESO CAR-T Studies, 2018
Table 7 1: China - CD19 Directed CAR-T Cells Clinical Trials, 2017
Table 7 2: China - Non-CD19 Directed CAR-T Cells Clinical Trials, 2017
Table 7 3: China - Solid Tumors CAR-T Cells Clinical Trials, 2017
Table 10 1: Global - Venture Capital Investments (Million US$) in CAR-T Cell Therapy, 2011 - 2017
Table 10 2: Global - Initial Public Offerings (Million US$) in CAR-T Cell Therapy, 2011 - 2016
Table 10 3: Global - CAR-T Companies Strategic Partnerships/Acquisitions, 2012-2017
Table 10 4: Global - Key CAR-T Technology Deals, 2012-2017
Note: Product cover images may vary from those shown
  • Novartis
  • Gilead Sciences (Kite Pharma)
  • Celgene Corporation (Juno Therapeutics)
  • Celyad
Note: Product cover images may vary from those shown

In this report, for analyzing the future trends for the studied market during the forecast period, the publisher has incorporated rigorous statistical and econometric methods, further scrutinized by secondary, primary sources and by in-house experts, supported through their extensive data intelligence repository. The market is studied holistically from both demand and supply-side perspectives. This is carried out to analyze both end-user and producer behavior patterns, in the review period, which affects price, demand and consumption trends. As the study demands to analyze the long-term nature of the market, the identification of factors influencing the market is based on the fundamentality of the study market.

Through secondary and primary researches, which largely include interviews with industry participants, reliable statistics, and regional intelligence, are identified and are transformed to quantitative data through data extraction, and further applied for inferential purposes. The publisher's in-house industry experts play an instrumental role in designing analytic tools and models, tailored to the requirements of a particular industry segment. These analytical tools and models sanitize the data & statistics and enhance the accuracy of their recommendations and advice.

Primary Research

The primary purpose of this phase is to extract qualitative information regarding the market from the key industry leaders. The primary research efforts include reaching out to participants through mail, tele-conversations, referrals, professional networks, and face-to-face interactions. The publisher also established professional corporate relations with various companies that allow us greater flexibility for reaching out to industry participants and commentators for interviews and discussions, fulfilling the following functions:

  • Validates and improves the data quality and strengthens research proceeds
  • Further develop the analyst team’s market understanding and expertise
  • Supplies authentic information about market size, share, growth, and forecast

The researcher's primary research interview and discussion panels are typically composed of the most experienced industry members. These participants include, however, are not limited to:

  • Chief executives and VPs of leading corporations specific to the industry
  • Product and sales managers or country heads; channel partners and top level distributors; banking, investment, and valuation experts
  • Key opinion leaders (KOLs)

Secondary Research

The publisher refers to a broad array of industry sources for their secondary research, which typically includes, however, is not limited to:

  • Company SEC filings, annual reports, company websites, broker & financial reports, and investor presentations for competitive scenario and shape of the industry
  • Patent and regulatory databases for understanding of technical & legal developments
  • Scientific and technical writings for product information and related preemptions
  • Regional government and statistical databases for macro analysis
  • Authentic new articles, webcasts, and other related releases for market evaluation
  • Internal and external proprietary databases, key market indicators, and relevant press releases for market estimates and forecasts
 

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