Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Part B, Volume 177 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, and more.
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Table of Contents
Preface�
David Teplow�
1. Relevance�of transgenic mouse models for�Alzheimer's disease�
Leon Tai, Juan Maldonado Weng, Mary Jo LaDu and Scott Brady�
2. Mitochondrial transplant to replenish damaged mitochondria: A novel therapeutic strategy for neurodegenerative diseases?
Abhisek Mukherjee, Andrea D Becerra Calixto, Melissa Chavez, Jean Paul Delgado Charris and Claudio Soto�
3. Activity-dependent�neuroprotective�protein�(ADNP)-end-binding�protein�(EB)�interactions�regulate�microtubule�dynamics�toward�protection�against�tauopathy�
Yanina�Ivashko-Pachima�and�Illana�Gozes�
4. Applying�available knowledge and resources to alleviate familial and sporadic neurodegenerative disorders�
Mark P. Mattson�
5. The�cellular machinery of post-endocytic�APP�trafficking in Alzheimer's disease: A�future target for therapeutic intervention?�
Lawrence S.B. Goldstein and Utpal Das�
6. The�search for novel targets in Alzheimer's disease-The 90s redux�
Christian�Behl�
7. Adult�hippocampal neurogenesis in Alzheimer's�disease�
Ahmed�Disouky�and�Orly�Lazarov�
8. Early�detection and personalized medicine: Future�strategies against Alzheimer's disease�
Antonio Di Meco and Robert Vassar�
9. Inflammation and Parkinson's�disease pathogenesis: Mechanisms�and therapeutic insight�
Gianluigi�Forloni, Pietro la Vitola, Milica�Cerovic�and Claudia Balducci�
