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Molecular Biology of Neurodegenerative Diseases: Visions for the Future - Part B. Progress in Molecular Biology and Translational Science Volume 177

  • Book

  • January 2021
  • Elsevier Science and Technology
  • ID: 5130650

Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Part B, Volume 177 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, and more.

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Table of Contents


David Teplow�

1. Relevance�of transgenic mouse models for�Alzheimer's disease�

Leon Tai, Juan Maldonado Weng, Mary Jo LaDu and Scott Brady�

2. Mitochondrial transplant to replenish damaged mitochondria: A novel therapeutic strategy for neurodegenerative diseases?

Abhisek Mukherjee, Andrea D Becerra Calixto, Melissa Chavez, Jean Paul Delgado Charris and Claudio Soto�

3. Activity-dependent�neuroprotective�protein�(ADNP)-end-binding�protein�(EB)�interactions�regulate�microtubule�dynamics�toward�protection�against�tauopathy�


4. Applying�available knowledge and resources to alleviate familial and sporadic neurodegenerative disorders�

Mark P. Mattson�

5. The�cellular machinery of post-endocytic�APP�trafficking in Alzheimer's disease: A�future target for therapeutic intervention?�

Lawrence S.B. Goldstein and Utpal Das�

6. The�search for novel targets in Alzheimer's disease-The 90s redux�


7. Adult�hippocampal neurogenesis in Alzheimer's�disease�


8. Early�detection and personalized medicine: Future�strategies against Alzheimer's disease�

Antonio Di Meco and Robert Vassar�

9. Inflammation and Parkinson's�disease pathogenesis: Mechanisms�and therapeutic insight�

Gianluigi�Forloni, Pietro la Vitola, Milica�Cerovic�and Claudia Balducci�