Copper in N-Heterocyclic Chemistry provides an overview of copper-catalyzed synthesis and functionalization of N-heterocyclic compounds, covering all recent developments in a way that is ideal for researchers and students working in the area of synthetic organic chemistry and medicinal chemistry. The book explores N-heterocyclic compounds as unique structural units in the development of natural products and pharmaceuticals, along with the remarkable progress made in the area of high atom economic strategies, and more recently, copper-catalyzed C-H activation and its applications in organic synthesis. Readers will find troubleshooting protocols, as well as the advantages and limitations of each method discussed.
As copper catalysts show versatile chemical reactivity in many aspects, including their oxidation states 0-3 are accessible and their ability to facilitate bond formations due to their ability to serve as Lewis acids, oxidizing agents and catalysts, this book is an ideal resource on the topics explored.
- Discusses novel synthetic methods developed over the past decade for copper-catalyzed synthesis of N-heterocyclic compounds
- Covers the most recent methodologies adapted in synthetic chemistry for applications in natural products and pharmaceuticals
- Includes troubleshooting protocols, as well as the advantages and limitations of each method discussed in detail
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1. Copper-Catalyzed Synthesis of Aziridines 2. Copper Catalysis for Imidazoles and Pyrazoles 3. Copper catalysis for Triazoles and Tetrazoles 4. Copper Catalysis for Pyridines and Pyrimidines 5. Copper Catalysis for Triazines 6. Copper Catalysis for Pyrazines and Quinoxalines 7. Copper catalysis for Quinolines and Isoquinolines 8. Copper-Mediated Synthesis of Quinazolines and Related Benzodiazines 9. Copper Catalysis for Large Rings 10. Copper Catalysis for Saturated N-Heterocycles via C-H Functionalization 11. Pursuit for Simple and Efficient Ligands Promoting Copper-Catalyzed Type Ullmann Reactions for N-aryl heterocycles and Aromatic Amines 12. Solid Supported Copper for N-heterocycles 13. Copper Catalysis for Biologically Active N-heterocycles
Dr Ananya Srivastava has done her Ph.D. in Synthetic Organic Chemistry at the Department of Chemistry, Indian Institute of Technology Delhi, India. Prior to this, she earned her master of science in chemistry with a gold medal from D.D.U. Gorakhpur University, Gorakhpur, India. Currently, she is employed as a Scientific officer at the National Institute of Pharmaceutical Education and Research, Guwahati, India. Her research contributions are highly interdisciplinary, spanning a wide range in synthetic organic chemistry, nano-catalysis, material characterization, and nanobiosensor. She has published her research work in the leading and representative journals of her research area. She has also presented her research work in various conferences and symposium including 2nd International Symposium on C-H Bond Activation, Rennes, France. She is the recipient of many prestigious awards and fellowships, including JRF and SRF from Council of Scientific & Industrial Research (CSIR), Government of India, invited visiting scholar under NRF fellowship, South Korea to work at Pusan National University, South Korea. She is also the editor of the journal Modern Chemistry & Applications, U.S.A. She has also worked as visiting scientist with Professor Yoon Bo Shim at Department of Chemistry, PNU, South Korea. She has also completed the Patent Law course from the Nalsar University of Law, Hyderabad, India.