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HLA from Benchtop to Bedside

  • ID: 5137728
  • Book
  • January 2021
  • 200 Pages
  • Elsevier Science and Technology
HLA from Benchtop to Bedside provides the reader with a comprehensive, concise and thoroughly up-to-date book focusing on the all aspects of the HLA system, including new techniques and methodologies. Each chapter will begin with bullet-point lists of principle learning points, include comprehensive references, along with validated links to international resources for the reader to use whether running tests in a laboratory or studying HLA. Written by a diverse range of international academics for professionals, researchers, undergraduate and graduate students. Dr. Arthur Bradley Eisenbrey is an experienced transplant pathologist who has held significant academic and leadership positions in the field. HLA from Benchtop to Bedside is written for organ and stem cell transplant professionals, histocompatibility laboratory professionals and staff, medical residents and fellows on transplant services, medical students and students in clinical laboratory science.
  • Reviews current knowledge surrounding the HLA system
  • Covers current methodologies and utilization of histocompatibility testing
  • Authored by a leader in the field of histocompatibility and transfusion medicine
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1. Introduction and some history
2. The structure of the Major Histocompatibility Complex and major HLA components
3. Nomenclature and naming conventions for HLA
4. The Crossmatch
5. HLA antibody detection (screening) and identification
6. HLA typing by serologic methods
7. HLA typing by molecular methods
8. Massively parallel (Next Generation) sequencing
9. HLA alleles, disease associations and HLA pharmacogenetics
10. Engraftment monitoring
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Eisenbrey, A. Bradley
Arthur Bradley Eisenbrey, MD, PhD is a Clinical Associate Professor of Pathology, Wayne State University School of Medicine and the University of Toledo College of Medicine and Health Sciences. Semi-retired Transplant Immunologist and Specialist in Transfusion Medicine. He formerly directed Immunogenetics (HLA) laboratories at the Detroit Medical Center/Wayne State University, William Beaumont Hospital, Royal Oak, MI, Gift of Life Michigan and Henry Ford Hospital, Detroit, MI. Retired as a Colonel in the reserves of the United States Air Force. Board Certified in Anatomic and Clinical Pathology with subspecialty Board Certification in Blood Banking/Transfusion Medicine. Has served as chairperson of national committees of the AABB and College of American Pathologists (CAP) and continues to serve as a laboratory inspector for the CAP.
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