The Neuroscience of Depression: Features, Diagnosis and Treatment, is a comprehensive reference to the diagnosis and treatment of depression. This book provides readers with the mechanisms of depression reflecting on the interplay between depression and the biological and psychosocial processes. A detailed introduction to various episodes of depression, from PTSD to post-partum depression is provided, followed by a thorough discussion on biomarkers in depression and how to diagnose depression including the Hamilton Depression Rating scale. This book also includes three full sections on treatment options for depression, including pharmacological, behavioral and other novel regimes. The Neuroscience of Depression: Features, Diagnosis and Treatment is the only resource for researchers and practitioners studying, diagnosis and treating of depression.
- Covers a pharmacological and behavioral treatment options
- Features sections on diagnosis and biomarkers of depression
- Discusses depression in children, teens and adults
- Contains information on comorbidity of physical and mental conditions
- Includes more than 250 illustrations and tables
I. Depression: Introductory Chapters 1. Clinical staging in depression 2. Neurodevelopmental theory of depression 3. Depression after pregnancy 4. Modeling maternal depression during pregnancy: Rodent models of Major Depressive Disorder with Peripartum Onset 5. Depression in mothers and mental health in children: Impact, risk factors and interventions 6. Depression in college students 7. Depression in disasters and traumatic events 8. Depression and associated Alzheimer s disease 9. Comorbidities of depression and Parkinson's disease 10. Understanding the relationship between depression and alcohol among students 11. Depression in obesity 12. Depression and heart rate variability 13. Neuroinflammation and depression 14. Interlinking antidepressants and the immune system
II. Biomarkers and Diagnosis 15. Assessment scoring tools of depression 16. The Beck Depression Inventory: Uses and applications 17. The Hamilton Depression Rating scale: Uses and applications 18. The Patient Health Questionnaire (PHQ) 19. Screening for Antenatal Depression (AND) using self-report questionnaires: Conceptual issues and measurement limitations 20. Edinburgh Postnatal Depression Scale: Description and applicationsJacqueline 21. The Death Depression Scale: Description and applications 22. Depression Anxiety Stress Scales: Features and Applications 23. Arabic version of the two-question Quick Inventory of Depression: Description and applications (QID-2-Ar) 24. Depressive Symptoms and Biomarkers of Cardiovascular Disease 25. Thioredoxin as an antioxidant protein as a marker in depression 26. Methods of neuroimaging in depression: Applications to resting-state functional connectivity 27. Neural markers of depression in MRI
III. Pharmacological Treatments for Depression 28. Angiotensin receptor 1 blockade as an antidepression strategy 29. Cannabinoid CB1 receptors and antidepressant effects 30. Agomelatine: profiles and applications to depression 31. Bumetanide and use in depressive states 32. Linking citalopram, serotonin reuptake inhibitors and depressed pregnant women 33. Citalopram and usage in sleep-deprivation-induced depression 34. Monoaminergic System and Antidepressants 35. Duloxetine usage in depression 36. Escitalopram and blonanserin as antidepressant agents linking in neurotrophic mechanisms 37. Ketamine and the role of (2R,6R)-Hydroxynorketamine in depression 38. Linking 5-Hydroxytryptamine, antidepressant actions of (R)-Ketamine and social stress model 39. Mirtazapine: Multi-target strategies for treating substance use disorder and depression
IV. Counselling, Psychotherapy and Behavioural Treatments for Depression 40. Mindfulness-based cognitive therapy and depression 41. Online (web based) programs for depression 42. Clay art therapy on emotion regulation: Research, theoretical underpinnings, and treatment mechanisms 43. Solution-focused counselling: and use in postpartum depression 44. Transcranial direct current stimulation (tDCS) combined with cognitive emotional training (CET) as a novel treatment for depression
V. Other Aspects of Treatment: Specific Groups, Monitoring and Novel Regimens 45. Putative effects of cannabidiol in depression and synaptic plasticity 46. Tanscutaneous vagus nerve stimulation in depression 47. Exercise for depression as a primary and comorbid with obesity disorder: A narrative 48. Acupressure and depression: a scientific narrative 49. Potential beneficial effects of Bifidobacterium breve A1 on cognitive impairment and psychiatric disorders 50. Coenzyme Q and use in depression 51. Gene expression in Major Depressive Disorder: peripheral and brain based studies 52. Electroconvulsive therapy for depression: effectiveness, cognitive side-effects and mechanisms of action 53. Depression and offspring DNA methylation 54. Other Aspects of Treatment: Specific Groups, Monitoring and Novel Regimens: Treating depression with Theta burst stimulation (TBS)
Dr. Martin is a Professor of Mental Health at Buckinghamshire New University. He is a Registered Nurse, Chartered Health Psychologist, and a Chartered Scientist. He has published or has in press well over 250 research papers and book chapters. He is a keen book author and editor having written and/or edited several books all of which reflect his diverse academic and clinical interests that examine in-depth, the interface between mental health and physical health. These outputs include the Handbook of Behavior; Food and Nutrition (2011), Perinatal Mental Health: A Clinical Guide (2012); Nanomedicine and the Nervous System (2012), and the major reference works Comprehensive Guide to Autism (2014), Diet and Nutrition in Dementia and Cognitive Decline (2015), Comprehensive Guide to Post-Traumatic Stress Disorder (2016) and Metabolism and Pathophysiology of Bariatric Surgery: Nutrition, Procedures, Outcomes, and Adverse Effects (2017).
Dr Lan-Anh Hunter BSc MBBS DFFP DRCOG MRCGP qualified from Guys, King's & St. Thomas' Medical School, London in 2001, where she developed an early interest in psychological medicine. She went on to study culture bound syndromes, whilst reading Medical Anthropology Honours degree at University College London, focusing on the cultural aspects of anorexia nervosa in her thesis. She subsequently worked in Australia and explored the psychological aspects of diabetes and its many complications on the aboriginal population. Prior to becoming a GP Principal, she lectured at Charing Cross Hospital teaching doctors in training, continuing this passion, as a GP trainer in her current role. Much has been written about depression in primary care and hence her call to this area. She specialises in psychological medicine, with training in coaching, narrative based medicine, cognitive behaviour therapy and she continues to see, support, treat and manage clinical depression on an everyday basis as a family GP in her Maidenhead practice.
Patel, Vinood B.
Dr. Patel is a Reader at the University of Westminster. After completing his PhD at King's College London, he continued his research experience by undertaking his post-doctoral studies in the laboratory of Professor Cunningham in the Department of Biochemistry at the Wake Forest University School of Medicine, (Winston-Salem, NC, USA). This extensive project involved investigating mechanisms of hepatic mitochondrial ribosome dysfunction in alcoholic liver disease (ALD) using biophysical and proteomic techniques. These studies have led to new avenues in determining the pathology of ALD. His teaching areas at both post-graduate and undergraduate levels include clinical biochemistry, investigative pathology and laboratory investigation.
Preedy, Victor R.
Dr. Preedy is a senior member of King's College London and Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well-being. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is an extremely experienced book editor, having edited influential works including but not limited to The Handbook of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse, The Handbook of Cannabis and Related Pathologies, The Neuroscience of Cocaine, and upcoming titles The Neuroscience of Alcohol, The Neuroscience of Nicotine, and more (all Elsevier).
Dr. Rajendram is a clinician scientist whose focus is on perioperative medicine, anesthesia, and intensive care. He graduated in 2001 with a distinction from Guy's, King's, and St. Thomas Medical School in London, and began his postgraduate medical training in general medicine and intensive care in Oxford. Dr. Rajendram returned to Oxford as a consultant in general medicine at the John Radcliffe Hospital, Oxford, before moving to the Royal Free London Hospitals as a consultant in intensive care, anesthesia, and perioperative medicine. He is currently a consultant in internal and perioperative medicine at King Abdulaziz Medical City, Riyadh, Saudi Arabia. As a visiting lecturer in the Division of Diabetes and Nutritional Sciences, King's College London, he has published over 100 textbook chapters, review articles, peer-reviewed papers, and abstracts.