Lignin-Based Materials for Biomedical Applications: Preparation, Characterization, and Implementation explores lignin-based materials as a platform for advanced biomedical applications, guiding the reader from source to implementation. Sections introduce the basics of lignin, including extraction methods, chemical modifications, structure, composition and properties, describe structural characterization techniques, focus on the preparation of lignin-based materials for biomedical applications, present methodologies for lignin-based nanoparticles, hydrogels, aerogels and nanofibers, and provide in-depth coverage of lignin-based materials with specific properties - including antioxidant properties, UV absorbing capability, antimicrobial properties, and colloidal particles with tailored properties. Finally, applications such as drug delivery, gene delivery and tissue engineering are explored.
This is an essential reference for all those with an interest in lignin-based materials and their biomedical applications, including researchers and advanced students across bio-based polymers, polymer science, polymer chemistry, biomaterials, nanotechnology, materials science and engineering, drug delivery, and biomedical engineering, as well as industrial R&D and scientists involved with bio-based polymers.
- Unlocks the potential of lignin-based materials with advanced properties for cutting-edge applications in areas such as drug delivery, gene delivery and tissue engineering
- Presents state-of-the-art methodologies used in the development of lignin-based nanoparticles, hydrogels, aerogels and nanofibers
- Explains the fundamentals of lignin, including structure and composition, extraction and isolation methods, types and properties, chemical modifications, and characterization techniques
1. Introduction to Lignocellulosic Materials 2. Structure and Composition of Lignin Polymer 3. Lignin Extraction and Isolation Methods 4. Types of Lignin, Properties and Structural Characterization Techniques 5. Chemical Modifications of Lignin 6. Requirements and Properties of Biomaterials for Biomedical Applications 7. Development of Lignin-based Nanoparticles: Fabrication Methods and Functionalization Approaches 8. Lignin-based Materials with UV Adsorbing Capability 9. Lignin-based Materials with Antioxidant and Antimicrobial Properties 10. Lignin Colloidal Particles for Pickering Emulsions 11. Lignin-based Materials for Drug and Gene Delivery 12. Fabrication of Lignin-based Hydrogels and their Applications 13. Methodologies to Develop Advanced Lignin-based Materials for Tissue Engineering 14. Present and Future Prospective of Lignin-based Materials
Hélder A. Santos is a Professor in Pharmaceutical Nanotechnology, Principal Investigator/Group Leader, Director of the Doctoral Program in Drug Research, and Head of the Nanomedicines and Biomedical Engineering Group at the Faculty of Pharmacy, University of Helsinki (Finland). Prof. Santos' research is focused on nanobiomaterials, including nanoporous silica/silicon materials and polymeric-based nanoparticles for controlled drug delivery, diagnostics and therapy. The research interests include the development of nanoparticles/nanomedicines for biomedical and healthcare applications. His current work makes the bridge between engineering, pharmaceutical and medical research. His main research focus is in the use of biodegradable and biocompatible nanoporous silicon nanomaterials, polymers, the application of microfluidics technology for nanoparticle production for simultaneous controlled drug delivery, diagnostic and treatment of cancer, diabetes, and cardiovascular diseases, and further translation of these technologies into the clinic. Prof. Santos is the author/co-author of more than 280 publications, including reviews, journal editorials, book chapters and 4 patents (> 8100 citations, h-index = 54), and more than 250 conference proceedings/abstracts.
Patrícia Figueiredo is a PhD student at the Division of Pharmaceutical Chemistry and Technology, University of Helsinki, Finland. Her research is focused on the development of lignin-based nanosystems for biomedical applications.