Protocol Handbook for Cancer Biology brings together a comprehensive collection of the methods used for cancer assessment, diagnostics, and therapeutics. Various protocols are discussed along with alternative strategies, including the advantages and limitations of techniques that have been used in labs globally. These protocols are presented by cancer biology experts based on their real-world experience. The protocols in this book will be a valuable resource for cancer researchers and graduate students, who can utilize the techniques described to conduct research more efficiently and successfully.
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Table of Contents
1. Overview of cancer assessment, diagnostics and therapeutics2. Cell viability and apoptic assays to assess drug efficacy3. Assays to assess the proliferative behavior of cancer cells4. Assays to evaluate tumor angiogenesis5. Assays and protocols for the detection of cancer metastasis6. Isolation and characterization of cancer stem cells 7. Histopathology-based cancer detection methods8. Molecular imaging in tumor diagnosis and treatment9. High throughput cell-based screening methods for cancer drug discovery10. Nanotechnology in cancer therapeutics: cerium oxide nanomaterials as cancer therapeutic agents
Authors
Gauri Misra Scientist Grade-II, National Institute of Biologicals, (Autonomous Institute under Ministry of Health andFamily Welfare), Government of India, Noida, Uttar Pradesh, India. Gauri Misra, PhD, has a research focus in the field of cancer biology and Malaria directed toward drug discovery, armored with an experience in Structural Biology, Biophysics and Bioinformatics. She has an outstanding academic background and experience of more than 10 years in the field of teaching and research, adorned by various prestigious awards and honors at different stages of her career with a strong desire of transferring her repertoire of knowledge to the upcoming generations. Her PhD thesis was awarded with Eli Lilly Asia Outstanding Thesis Award (first prize) in 2009. She has received "state of the art� International exposure while working as a postdoctoral researcher at CHUL Research Centre, Canada and visiting scientist at ISPC, Weizmann Institute of Science, Rehovot, Israel in 2014 along with few other countries. She serves as a reviewer for various renowned international journals and is often invited for speaking engagements about her research. To date, she has authored 17 research articles, 4 international books, and 6 book chapters. The ongoing research project in her laboratory focuses on evaluating the potential of new lead compounds against breast cancer. Jyotika Rajawat Research Scientist, DST WOS-A project, Lucknow, Uttar Pradesh, India. Jyotika Rajawat, PhD, researches in the field of cancer and drug discovery. She has a rich experience of 8 years in cancer research and teaching. Her postdoctoral research at CHUQ Research Centre, Canada, followed by research projects at National Centre for Cell Science (Pune), CSIR- Central Drug Research Institute (Lucknow), India has established a novel role of PARP1 protein in cancer progression. She has written several research articles, three book chapters, and newspaper articles. She is a member of the Editorial Board, IJBST journal and is a reviewer for various international publishers. She has been the recipient of several awards including DBT Bio-CARe and DST Women Scientist Award (awarded by the Govt. of India). She is also passionate about conducting cancer awareness workshops and literacy camps for the underprivileged especially in the rural areas. Dr. Rajawat being an expert in cancer biology understands the needs of readers and writes with those needs in mind.
