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Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems

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    Report

  • 174 Pages
  • June 2023
  • Region: Global
  • BCC Research
  • ID: 5230108

The scope of the report includes an overview of the global market for nanoparticles in biotechnology, drug development and formulation, drug delivery systems, and diagnostics as well as analyses of global market trends, using 2022 as the base year and forecasting market sizes for 2023 through 2028 with compound annual growth rate (CAGR) projections.

The report includes an analysis of leading and emerging drug products for each nanoparticle type. Profiles of manufacturers of leading products and their specific products are provided. This report also assesses companies poised to introduce products during the forecast period and discusses how these introductions will change the face of the competitive environment. The competitive environment is examined with a special focus on how new products will alter the quality of life of patients receiving nanoparticle-associated drugs.

Market figures are based on revenues at the manufacturer level and are projected in dollar value. Inflation is not computed into the projection figures. Trends are assessed based on projected sales for existing products, new product introductions, expanded markets for existing products, and other factors affecting the market.

The study is arranged to offer an overview of existing nanoparticle technology and drug markets; it is accompanied by nanoproduct, company, geography, and mechanism of action, with forecasts broken down and covered by geographic regions and countries. Patent and clinical trial information is reviewed for various candidate nanodrugs. The status of approvals of drugs in each segment by the FDA and regulatory agencies in other countries is reviewed.

Figures are reported in U.S. dollars and each case reflects currency fluctuations within the performance of revenue change. Revenue figures do not account for variations in local currencies. All market share data presented is on a global basis unless specifically mentioned.

Regional analysis includes North America (U.S., Canada, Mexico), Europe (U.K., Germany, France, Spain, Italy, and the Rest of Europe), Asia-Pacific (China, India, Japan, and Rest of Asia-Pacific), and the Rest of the world (South America, and the Middle East and Africa).

Report Includes

  • 25 data tables and 40 additional tables
  • An updated overview and in-depth analysis of the global markets for nanoparticles in biotechnology, drug development and drug delivery systems
  • Analyses of the global market trends, with historical market revenue data (sales figures) from 2020 to 2022, estimates for 2023, and projections of compound annual growth rates (CAGRs) through 2028
  • Estimation of the actual market size and revenue forecast for nanoparticles in biotechnology, drug development and drug delivery systems market, and corresponding market share analysis by technology, application and region
  • Highlights of the drug development, formulation, and the development of new drug delivery systems and detailed product analyses within health and wellness subsegments
  • In-depth information (facts and figures) concerning the major factors influencing the progress of the market (benefits and industry-specific challenges) with respect to specific growth trends, upcoming technologies, prospects, and contributions to the overall market
  • Discussion on the role of nanotechnology in the COVID-19 vaccine production, mechanism of action, components and methods in vaccine design for COVID-19 and challenges for vaccine disruptions
  • Review of the leading and emerging drug products for each nanoparticle type, clinical trial landscape for various candidate nanodrugs, status of approvals of drugs in each segment, and penetration of technologies and research initiatives within the ecosystem
  • Updated information on patents and patent applications on nanoparticles in biotechnology, drug development and drug delivery systems, and related scientific publications
  • Identification of the major stakeholders and analysis of the competitive landscape based on recent developments, financial performances, and segmental revenues
  • Descriptive company profiles of the leading global players in the market, including Bristol-Myers Squibb Co., Camurus, GlaxoSmithKline PLC, Merck & Co. Inc. and Novartis AG
Frequently Asked Questions about the Global Nanoparticles in Biotechnology Market

What is the estimated value of the Global Nanoparticles in Biotechnology Market?

The Global Nanoparticles in Biotechnology Market was estimated to be valued at $102.7 Billion in 2023.

What is the growth rate of the Global Nanoparticles in Biotechnology Market?

The growth rate of the Global Nanoparticles in Biotechnology Market is 8.8%, with an estimated value of $156.8 Billion by 2028.

What is the forecasted size of the Global Nanoparticles in Biotechnology Market?

The Global Nanoparticles in Biotechnology Market is estimated to be worth $156.8 Billion by 2028.

Who are the key companies in the Global Nanoparticles in Biotechnology Market?

Key companies in the Global Nanoparticles in Biotechnology Market include Bristol, Myers Squibb Co., Camurus Ab, Ceramisphere Health Pty Ltd., Cytimmune Sciences, Gilead Sciences Inc., GlaxoSmithKline plc, Hoffmann, La Roche Inc. and Merck & Co. Inc..

Table of Contents

Chapter 1 Introduction
  • Study Goals and Objectives
  • Reasons for Doing this Study
  • What's New in this Report?
  • Scope of Report
  • Methodology
  • Market Estimate
  • Information Sources
  • Primary Research
  • Secondary Research
  • Geographic Breakdown
  • Market Segmentation
  • Analyst's Credentials
  • Custom Research
  • Related Research Reports
Chapter 2 Summary and Highlights
Chapter 3 Market Overview
  • Introduction to Nanoparticles
  • Liposomes
  • Quantum Dots
  • Dendrimers
  • Macromolecule Nanoparticles
  • Brief History of Nanoparticles
  • Nanoparticles in Biotechnology
  • Nanoparticles in Drug Development
  • Nanoparticles in Drug Delivery Systems
  • Nanoparticles in Diagnostic Imaging
  • Major Players in the Nanoparticle Drug Delivery Field
  • Major Nanoparticle/Nanocrystal Drugs
  • Market Dynamics
  • Drivers
  • Restraints
  • Pestel Analysis
  • Regulatory Landscape
  • U.S.
  • Europe
  • India
  • Emerging Technologies in Nanoparticles
  • Gadolinium-Neutron Capture Therapy (Gd-Nct) for Glioblastoma Multiforme (Gbm) Treatment
  • Ligand-Tethered Lipid Nanoparticles for Targeted Rna Delivery to Treat Liver Fibrosis
Chapter 4 Role of Nanotechnology in Covid-19 Vaccine Production
  • Introduction
  • Fight Against Novel Coronavirus
  • Structure of Covid-19 and Penetration
  • Challenges for Covid-19 Vaccines
  • Components and Methods in the Design of Vaccines
  • Antigen
  • Adjuvant
  • Nanoparticle/Nanocarrier
  • Device
  • Next-Generation Vaccines Enabled Through Advances in Nanotechnology
  • Conclusion on Nanotechnology Use Against Covid-19
Chapter 5 Global Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems by Technology
  • Technology Overview
  • Liposomes
  • Polymeric Micelles
  • Dendrimers
  • Others
Chapter 6 Global Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems by Application
  • Biotechnology
  • Drug Development and Formulation
  • Drug Delivery Systems
  • Diagnostic Imaging
Chapter 7 Structure of Nanoparticles
  • Adoption of Nanoparticles in Applied Markets
  • Liquid Crystals
  • Liquid Carriers
  • Liposomes
  • Dendrimers
  • Chitosan and Alginate
  • Nanocrystals
  • Quantum Dots
  • Application of Nanoparticles to Drugs Delivered
Chapter 8 Production of Nanoparticles
  • Methods of Nanoparticle Formation
  • Self-Assembly Production
  • Methods of Stabilization
  • Methods of Drug Introduction
  • Polymeric Nanoparticles
  • Micelles
  • Liposomes
  • Gold and Silicon Nanoparticles
  • Dendrimers
  • Methods for Loading Biological Molecules into Nanoparticles
  • Nanocrystal Drugs
  • Problems With Large-Scale Nanoparticle Production
Chapter 9 Nanoparticles in Biotechnology
  • Research and Development
  • Stem Cell Research
  • Cellular Repair
  • Paramagnetic and Superparamagnetic Nanoparticles
  • Biosensors and Quantum Dots
  • Nanoparticle Research Collaborative Programs
Chapter 10 Nanoparticles in Drug Development and Formulation
  • Bio Separations
  • Rapid Drug Analysis
  • Removal of Impurities and Toxins
  • Using Nanoparticles to Incorporate Insoluble Drugs
  • Gold and Silver Nanoparticles in Biomedicine
  • DNA Nanoparticle Development of DNA-Specific Drugs
Chapter 11 Nanoparticles in Drug Delivery Systems
  • Nanoparticles in Drug Delivery Applications
  • Designing a Nanoparticle Drug Delivery System
  • Nanoparticle Drug Stability
  • Size Homogeneity of Nanoparticle Preparations
  • Drug Loading of Nanoparticles
  • Drug Release from Nanoparticles
  • External Triggers for Releasing Drugs from Nanoparticles
  • Binding/Incorporation of Biomolecules to Nanoparticles
  • Nanoparticle Toxicity
  • Large-Scale Manufacturing
  • Methods of Administration of Nanoparticle Drugs
  • Oral Administration
  • Injection Administration
  • Transdermal Patch
  • Implantation Administration
  • Inhalation Administration
  • Nanoparticles Suitable for Drug Delivery Systems
  • Lipid-Based Nanoparticles
  • Micelle Nanoparticles
  • Dendrimer Nanoparticles
  • Polymeric Nanoparticles
  • Metal-Based Nanoparticles
  • Biological Macromolecule Nanoparticles
  • Nanocrystals
  • Nanoparticle Drug Delivery Systems Now Available
  • Antibiotic Nanoparticles
  • Anti-Tumor and Small Molecule Delivery by Nanoparticle
  • Release of Anti-Cancer Drugs from Nanoparticles
  • Biomacromolecules Delivered by Nanoparticles
  • Nanoparticles Coating for Drug Delivery Systems
  • Removal of Nanoparticles from the Body
Chapter 12 in-Vitro and in Vivo Diagnostic Imaging
  • In Vitro Imaging
  • Nanoparticles in Diagnostic Imaging
Chapter 13 Global Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems by Region
  • Market Overview and Discussion
  • North America
  • Europe
  • Asia-Pacific
  • Rest of the World
  • South America
  • Middle East and Africa
Chapter 14 Competitive Landscape
  • Nanoparticle Drug Delivery Systems and Products
  • Major Players in Nanoparticle Drug Delivery Systems
  • Company Pipelines for Nanoparticle Drug Delivery
  • Drivers of Nanoparticle Products and Marketing
  • Limiters of Nanoparticle Product Development and Marketing
Chapter 15 Patents, Licensing, Mergers and Acquisitions
  • Recent Licensing Activity, Mergers, and Acquisition
  • Recent Deals
  • Nanoparticle Patents
Chapter 16 Company Profiles
  • Bristol-Myers Squibb Co.
  • Camurus Ab
  • Ceramisphere Health Pty Ltd.
  • Cytimmune Sciences
  • Gilead Sciences Inc.
  • GlaxoSmithKline plc
  • Hoffmann-La Roche Inc.
  • Merck & Co. Inc.
  • Nanocarrier Co. Ltd.
  • Novartis Ag
List of Tables
Summary Table A: Global Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Application, Through 2028
Summary Table B: Global Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Technology, Through 2028
Table 1: Description of Nanoparticles Used in Drug Delivery and Diagnostic Imaging
Table 2: Applications of Nanoparticles in Biotechnology
Table 3: Applications of Nanoparticles in Drug Development
Table 4: Applications of Nanoparticles in Drug Delivery Systems
Table 5: Nanoparticles Used in Drug Delivery Systems
Table 6: Nanoparticles Used for In Vivo Diagnostic Imaging
Table 7: Major Players in the Nanoparticle Drug Field
Table 8: Major Nanoparticle/Nanocrystal Drug, by Product and Company
Table 9: Description of Nanomaterial Properties and Associated Risks
Table 10: Global Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Technology, Through 2028
Table 11: Global Market for Liposomes Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Region, Through 2028
Table 12: Patents Related to Polymeric Micelles and Their Drug Delivery Applications, 2022
Table 13: Global Market for Polymeric Micelles Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Region, Through 2028
Table 14: Global Market for Dendrimers Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Region, Through 2028
Table 15: Global Market for Other Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Region, Through 2028
Table 16: Global Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Application, Through 2028
Table 17: Global Market for Nanoparticles in Biotechnology, by Region, Through 2028
Table 18: Global Market for Nanoparticles in Drug Development and Formulation, by Region, Through 2028
Table 19: Global Market for Nanoparticles in Drug Delivery Systems, by Region, Through 2028
Table 20: Global Market for Nanoparticles in Diagnostics, by Region, Through 2028
Table 21: Nanoparticles Structure and Properties
Table 22: Nanoparticles Systems Approved for Drug Delivery
Table 23: Sample of Drugs Delivered Through Liposome Nanotechnology
Table 24: Nanoparticles in Biotechnology Applications
Table 25: Nano Biosensor Technology Under Development
Table 26: ETPN Strategic Research and Innovation Agenda
Table 27: Nanoparticles in Drug Development Applications
Table 28: Monoclonal antibody (mAb) Drugs with Potential for Use in Nanoparticles Delivery Systems
Table 29: Solid Lipid Nanoparticles-Reformatted Drugs
Table 30: Nanoparticles in Drug Delivery Applications
Table 31: Standard Routes of Drug Administration
Table 32: Nanoparticle Transdermal Patch Products
Table 33: Type of Nanoparticles Supplied in Drug Delivery Systems
Table 34: Mechanism for Removal of Nanoparticles from the Body
Table 35: Nanoparticles Contrast Media Used for In Vivo Diagnostic Imaging
Table 36: Global Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery, by Region, Through 2028
Table 37: North American Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Country, Through 2028
Table 38: European Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Country, Through 2028
Table 39: Asia-Pacific Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Country, Through 2028
Table 40: List of Marketed Products Used in Different Nanotechnology-based Techniques
Table 41: Major Players in Nanoparticle Drug Development and Formulation Market
Table 42: Company Pipeline for Cardiovascular Nanoparticle Drugs
Table 43: Company Pipeline for CNS Disease Nanoparticle Drugs
Table 44: Company Pipeline for GI Disease Nanoparticle Drugs
Table 45: Company Pipeline for Infectious Disease Nanoparticle Drugs
Table 46: Company Pipeline for Cancer Nanoparticle Drugs
Table 47: Company Pipeline for Ophthalmic Nanoparticle Drugs
Table 48: Company Pipeline for Autoimmune Disease Nanoparticle Drugs
Table 49: Global Nanotechnology Patents, by Country, 2020-2023
Table 50: Bristol-Myers Squibb Co.: Financials, 2020-2022
Table 51: Camurus: Financials, 2020-2022
Table 52: Camurus: Developments, 2020-2022
Table 53: Cytimmune Sciences: Developments, 2020-2022
Table 54: Gilead Sciences Inc.: Financials, 2020-2022
Table 55: Gilead Sciences Inc.: Developments, 2020-2022
Table 56: GlaxoSmithKline PLC: Financials, 2020-2022
Table 57: GlaxoSmithKline PLC: Developments, 2020-2022
Table 58: Hoffmann-La Roche Inc.: Financials, 2020-2022
Table 59: Merck & Co. Inc.: Financials, 2020-2022
Table 60: Merck & Co. Inc.: Developments, 2020-2022
Table 61: NanoCarrier Co., Ltd.: Financials, 2020-2022
Table 62: NanoCarrier Co., Ltd.: Developments, 2020-2022
Table 63: Novartis AG: Financials, 2020-2022

List of Figures
Summary Figure A: Global Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Application, 2020-2028
Summary Figure B: Global Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Technology, 2020-2028
Figure 1: PESTEL Analysis: Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems Market
Figure 2: Global Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Region, 2020-2028
Figure 3: Global Market Shares for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Region, 2023
Figure 4: North American Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, 2020-2028
Figure 5: North American Market Shares of Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Country, 2023
Figure 6: European Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, 2020-2028
Figure 7: European Market Shares of Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Country, 2023
Figure 8: Asia-Pacific Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, 2020-2028
Figure 9: Asia-Pacific Market Shares of Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, by Country, 2023
Figure 10: South American Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, 2020-2028
Figure 11: Middle Eastern and African Market for Nanoparticles in Biotechnology, Drug Development, and Drug Delivery Systems, 2020-2028
Figure 12: Bristol-Myers Squibb Co.: Research and Development Expenses, 2020-2022
Figure 13: Bristol-Myers Squibb Co.: Revenue Share, by Region, 2021
Figure 14: Camurus: Research and Development Expenses, 2020-2022
Figure 15: Camurus: Revenue Share, by Region, 2022
Figure 16: Camurus: SWOT Analysis
Figure 17: Gilead Sciences Inc.: Research and Development Expenses, 2020-2022
Figure 18: Gilead Sciences Inc.: Revenue Share, by Product Sales, 2022
Figure 19: GlaxoSmithKline PLC: Research and Development Expenses, 2020-2022
Figure 20: GlaxoSmithKline PLC: Revenue Share, by Segment, 2021
Figure 21: GlaxoSmithKline PLC: SWOT Analysis
Figure 22: Hoffman-La Roche Inc.: Research and Development Expenses, 2020-2022
Figure 23: Hoffman-La Roche Inc.: Revenue Share, by Segment, 2022
Figure 24: Merck & Co. Inc.: Research and Development Expenses, 2020-2022
Figure 25: Merck & Co. Inc.: Revenue Share, by Segment, 2022
Figure 26: Merck & Co. Inc.: SWOT Analysis
Figure 27: NanoCarrier Co., Ltd.: Net Assets, 2020-2022
Figure 28: Novartis AG: Operating Income, 2020-2022
Figure 29: Novartis AG: Revenue Share, by Segment, 2022
Figure 30: Novartis AG: SWOT Analysis

Executive Summary

Nanoparticle technology has made major advances in particle types, production, and application in all areas of the life sciences in the past two decades. The most rapid advances have been made in the application of nanoparticles in drug research and development, drug formulation, and the development of novel drug delivery systems using nanoparticle carriers. The development of nanoparticles and their rapid incorporation into research and development has also given rise to a new area of application in biotechnology and diagnostics involving particle materials in the nanometer size range.

Nanoparticles used in life sciences applications are usually considered to be in the range of 10 nanometers to 100 nanometers in diameter. The size and shape of nanoparticles is an important aspect to determine their properties and influences the drug performance and efficacy on the body. Developing particles from various starting materials that remain stable in this size range has become one of the fastest-growing and most potentially useful emerging technologies in the last several decades.

The nanoparticles market has been witnessing increased popularity in the field of life sciences applications mainly due to extensive research and favorable clinical trial results. Currently, North America holds the largest number of patents in the nanoparticle area. This is largely due to the early commercialization of some nanoparticle products by U.S.-based companies. It also demonstrates the major contribution of this region in the research and development of new technologies and drugs compared to other regions. Europe is the second-largest market for nanoparticle drug technology. France, Germany, and the U.K. are the major contributors to its market share. Drug formulation and drug delivery systems are major application areas that are lucrative for startups in Europe, thus contributing to the market’s growth.

The methods for producing nanoparticles vary depending on the starting substrate materials and the size particle desired as a product. This report will provide an overview of various production methods and indicate new advances in the production area.

Companies Mentioned

  • Bristol-Myers Squibb Co.
  • Camurus Ab
  • Ceramisphere Health Pty Ltd.
  • Cytimmune Sciences
  • Gilead Sciences Inc.
  • GlaxoSmithKline plc
  • Hoffmann-La Roche Inc.
  • Merck & Co. Inc.
  • Nanocarrier Co. Ltd.
  • Novartis Ag