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Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems

  • ID: 5230108
  • Report
  • December 2020
  • Region: Global
  • 137 Pages
  • BCC Research

FEATURED COMPANIES

  • Bristol-Myers Squibb Co.
  • Camurus Ab
  • Ceramisphere Pty Ltd.
  • Cytimmune Sciences
  • Glaxosmithkline Plc.
  • Hoffmann-La Roche Inc.

Report Scope:

The scope of the report includes an overview of the global market for nanoparticles in biotechnology, drug development, and drug delivery, and analyses of global market trends, using 2019 as the base year and forecasting 2020 through 2025 with compound annual growth rate (CAGR) projections.

The report includes an analysis of leading and emerging drug products for each nanoparticle type. Profiles of manufacturers of leading products and their specific products are provided. This report also assesses companies poised to introduce products during the forecast period and discusses how these introductions will change the face of the competitive environment. The competitive environment is examined with a special focus on how new products will alter the quality of life of patients receiving nanoparticle-associated drugs.

Market figures are based on revenues at the manufacturer level and are projected in 2019 dollar value. Inflation is not computed into the projection figures. Trends are assessed based on projected sales for existing products, for new product introductions, expanded markets for existing products, and other factors affecting the market included in this report are forecasted by product, product category, and company.

The study is arranged to offer an overview of existing nanoparticle technology and of drug markets; it is accompanied by nanoproduct, company, geography, and mechanism of action, with forecasts broken down and covered by geographic region or country.

Patent and clinical trial information are reviewed for various candidate nano-drugs. The status of approvals of drugs in each segment by the FDA and regulatory agencies in other countries is reviewed.

Figures are reported in U.S. dollars and in each case reflect currency fluctuations within the performance of revenue change. Revenue figures do not account for variation in local currencies. All market share data presented is on a global basis unless specifically noted.

Regional analysis includes North America (U.S., Canada, Mexico), Europe (U.K., Germany, France, Spain, Italy, Rest of Europe), Asia-Pacific (China, India, Japan, and Rest of Asia-Pacific), and the Rest of the world (South America, and the Middle East and Africa).

The Report Includes:

  • 43 tables
  • An overview of the global nanoparticles in biotechnology, drug development, and drug delivery market
  • Estimation of the market size and analyses of market trends, with data from 2019, estimates for 2020, and projection of CAGR through 2025
  • Highlights of the drug development, formulation, and the development of new drug delivery systems and detailed product analyses within health and wellness subsegments
  • Information on nanomedicine and biomedical nanoparticle products and coverage of the next-generation vaccines
  • Evaluation of current market trends, market size, market forecast, and detailed analysis of drivers, challenges, and opportunities affecting the market growth
  • Discussion on the role of nanotechnology in COVID-19 vaccine production, components, and methods in the vaccine design for COVID-19 and challenges for vaccine disruptions
  • Assessment of various approaches for the treatment of COVID-19, and detailed description of structure and penetration of coronavirus
  • Details of clinical trials of nanoparticle drugs and drug delivery systems
  • A look at the patents, licensing, mergers and acquisitions, and market share analysis of the key companies of the industry
  • Company profiles of major players including Bristol-Myers Squibb Co., GlaxoSmithKline PLC, Hofmann-La Roche Inc., Merck & Co., and Novartis AG
Note: Product cover images may vary from those shown

FEATURED COMPANIES

  • Bristol-Myers Squibb Co.
  • Camurus Ab
  • Ceramisphere Pty Ltd.
  • Cytimmune Sciences
  • Glaxosmithkline Plc.
  • Hoffmann-La Roche Inc.

Chapter 1 Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Methodology
  • Market Estimate
  • Information Sources
  • Primary Research
  • Secondary Research
  • Geographic Breakdown
  • Analyst's Credentials
  • Custom Research
  • Related Reports

Chapter 2 Summary and Highlights

Chapter 3 Market Overview

  • Introduction to Nanoparticles
  • Liposomes
  • Quantum Dots
  • Dendrimers
  • Macromolecule Nanoparticles
  • Brief History of Nanoparticles
  • Nanoparticles in Biotechnology
  • Nanoparticles in Drug Development
  • Nanoparticles in Drug Delivery Systems
  • Nanoparticles in Diagnostic Imaging
  • Major Players in Nanoparticle Drug Delivery Field
  • Major Nanoparticle/Nanocrystal Drug Revenues

Chapter 4 Market Breakdown by Product Type

  • Nanoparticles in Biotechnology
  • Nanoparticles in Drug Development
  • Nanoparticles in Drug Delivery Systems
  • Nanoparticles in Diagnostic Imaging
  • Distribution of Nanobiotechnology and Nanomedicine Companies

Chapter 5 Structure of Nanoparticles

  • Adoption of Nanoparticles in Applied Markets
  • Liquid Crystals
  • Liquid Carriers
  • Liposomes
  • Dendrimers
  • Chitosan and Alginate
  • Nanocrystals
  • Quantum Dots
  • Application of Nanoparticles to Drugs Delivered

Chapter 6 Production of Nanoparticles

  • Methods of Nanoparticle Formation
  • Self-Assembly Production
  • Methods of Stabilization
  • Methods of Drug Introduction
  • Polymeric Nanoparticles
  • Micelles
  • Liposomes
  • Gold and Silicon Nanoparticles
  • Dendrimers
  • Methods for Loading Biological Molecules into Nanoparticles
  • Nanocrystal Drugs
  • Problems with Large-Scale Nanoparticles Production

Chapter 7 Nanoparticles in Biotechnology

  • Research and Development
  • Stem Cell Research
  • Cellular Repair
  • Paramagnetic and Superparamagnetic Nanoparticles
  • Biosensors and Quantum Dots
  • Nanoparticle Research Collaborative Programs

Chapter 8 Nanoparticles in Drug Development and Formulation

  • Bio Separations
  • Rapid Drug Analysis
  • Removal of Impurities and Toxins
  • Using Nanoparticles to Incorporate Insoluble Drugs
  • Gold and Silver Nanoparticles in Biomedicine
  • DNA Nanoparticle Development of DNA-Specific Drugs

Chapter 9 Nanoparticles in Drug Delivery Systems

  • Nanoparticles in Drug Delivery Applications
  • Designing a Nanoparticle Drug Delivery System
  • Nanoparticle Drug Stability
  • Size Homogeneity of Nanoparticle Preparations
  • Drug Loading of Nanoparticles
  • Drug Release from Nanoparticles
  • External Triggers for Releasing Drugs from Nanoparticles
  • Binding/Incorporation of Biomolecules to Nanoparticles
  • Nanoparticle Toxicity
  • Large Scale Manufacturing
  • Methods of Administration of Nanoparticle Drugs
  • Oral Administration
  • Injection Administration
  • Transdermal Patch
  • Implantation Administration
  • Inhalation Administration
  • Nanoparticles Suitable for Drug Delivery Systems
  • Lipid-Based Nanoparticles
  • Micelle Nanoparticles
  • Dendrimer Nanoparticles
  • Polymeric Nanoparticles
  • Metal-Based Nanoparticles
  • Biological Macromolecule Nanoparticles
  • Nanocrystals
  • Nanoparticle Drug Delivery Systems Now Available
  • Antibiotic Nanoparticles
  • Anti-Tumor and Small Molecule Delivery by Nanoparticle
  • Release of Anti-Cancer Drugs from Nanoparticles
  • Biomacromolecules Delivered by Nanoparticles
  • Nanoparticles Coating for Drug Delivery Systems
  • Removal of Nanoparticles from the body

Chapter 10 In Vitro and In Vivo Diagnostic Imaging

  • In Vitro Imaging
  • Nanoparticles in Diagnostic Imaging

Chapter 11 Biomedical Nanoparticle Products

  • Nanoparticle Drug Delivery Systems and Products
  • Major Players in Nanoparticle Drug Delivery Systems
  • Company Pipelines for Nanoparticle Drug Delivery
  • Drivers of Nanoparticle Products and Marketing
  • Limiters of Nanoparticle Product Development and Marketing

Chapter 12 Market Breakdown by Region

  • Market Overview and Discussion
  • North America
  • Europe
  • Asia-Pacific
  • Rest of the World
  • South America
  • Middle East and Africa

Chapter 13 Role of Nanotechnology in COVID-19 Vaccine Production

  • Introduction
  • Novel Coronavirus Relying on Various Approaches
  • Structure of COVID-19 and Penetration
  • Challenges for COVID-19 Vaccines
  • Components and Methods in the Design of Vaccines
  • Antigen
  • Adjuvant
  • Nanoparticle/Nanocarrier
  • Device
  • Next-Generation Vaccines Enabled Through Advances in Nanotechnology
  • Conclusion on Nanotechnology Usage Against COVID-19

Chapter 14 Patents, Licensing, Mergers, and Acquisitions

  • Recent Licensed, Mergers and Acquisition
  • Recent Licensing Activity, Mergers and Acquisition
  • Recent Deals
  • Nanoparticle Patents

Chapter 15 Company Profiles

  • Bristol-Myers Squibb Co.
  • Camurus Ab
  • Ceramisphere Pty Ltd.
  • Cytimmune Sciences
  • Glaxosmithkline Plc.
  • Hoffmann-La Roche Inc.
  • Merck & Co. Inc.
  • Nanocarrier Co. Ltd.
  • Novartis Ag

List of Tables
Summary Table: Global Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery, by Product Type, Through 2025
Table 1: Description of Nanoparticles Used in Drug Delivery and Diagnostic Imaging
Table 2: Applications of Nanoparticles in Biotechnology
Table 3: Applications of Nanoparticles in Drug Development
Table 4: Applications of Nanoparticles in Drug Delivery Systems
Table 5: Nanoparticles Used in Drug Delivery Systems
Table 6: Nanoparticles Used for In vivo Diagnostic Imaging
Table 7: Major Players in Nanoparticle Drug Field
Table 8: Major Nanoparticle/Nanocrystal Drug by Product and Company
Table 9: Global Market for Nanoparticles in Biotechnology, Through 2025
Table 10: Global Market for Nanoparticles in Drug Development and Formulation, Through 2025
Table 11: Global Market for Nanoparticles in Drug Delivery Systems, Through 2025
Table 12: Global Market for Nanoparticles in Diagnostic Imaging Systems, Through 2025
Table 13: Global Distribution of Nanobiotechnology and Nanomedicine Companies
Table 14: Nanoparticles Structure and Properties
Table 15: Nanoparticles Systems Approved for Drug Delivery
Table 16: Sample of Drugs Delivered Through Liposome Nanotechnology
Table 17: Nanoparticles in Biotechnology Applications
Table 18: Nano Biosensor Technology Under Development
Table 19: ETPN Strategic Research and Innovation Agenda
Table 20: Nanoparticles in Drug Development Applications
Table 21: Monoclonal antibody (mAb) Drugs with Potential for Use in Nanoparticles Delivery Systems
Table 22: Solid Lipid Nanoparticles-Reformatted Drugs
Table 23: Nanoparticles in Drug Delivery Applications
Table 24: Standard Routes of Drug Administration
Table 25: Nanoparticle Transdermal Patch Products
Table 26: Type of Nanoparticles Supplied in Drug Delivery Systems
Table 27: Mechanism for Removal of Nanoparticles from the Body
Table 28: Nanoparticles Contrast Media Used for In Vivo Diagnostic Imaging
Table 29: List of Marketed Products Used in Different Nanotechnology-based Techniques
Table 30: Major Players in Nanoparticle Drug Development and Formulation Market
Table 31: Company Pipeline for Cardiovascular Nanoparticle Drugs
Table 32: Company Pipeline for CNS Disease Nanoparticle Drugs
Table 33: Company Pipeline for GI Disease Nanoparticle Drugs
Table 34: Company Pipeline for Infectious Disease Nanoparticle Drugs
Table 35: Company Pipeline for Cancer Nanoparticle Drugs
Table 36: Company Pipeline for Ophthalmic Nanoparticle Drugs
Table 37: Company Pipeline for Autoimmune Disease Nanoparticle Drugs
Table 38: Global Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery, by Region, Through 2025
Table 39: North American Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, by Country, Through 2025
Table 40: European Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, by Country, Through 2025
Table 41: Asia-Pacific Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, by Country, Through 2025
Table 42: Global Nanotechnology, Patents, by Country, 2017-2020
Table 43: Bristol-Myers Squibb Co.: Financials, 2017-2019

List of Figures
Summary Figure: Global Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery, by Product Type, 2019-2025
Figure 1: Global Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, 2019-2025
Figure 2: Global Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, by Region, 2019-2025
Figure 3: Global Market Share for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, by Region, 2019
Figure 4: North American Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, 2019-2025
Figure 5: North American Market Shares of Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, by Country, 2019
Figure 6: European Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, 2019-2025
Figure 7: European Market Shares of Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, by Country, 2019
Figure 8: Asia-Pacific Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, 2019-2025
Figure 9: Asia-Pacific Market Shares of Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, by Country, 2019
Figure 10: South American Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, 2019-2025
Figure 11: Middle Eastern and African Market for Nanoparticles in Biotechnology, Drug Development and Drug Delivery Systems, 2019-2025

Note: Product cover images may vary from those shown

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FEATURED COMPANIES

  • Bristol-Myers Squibb Co.
  • Camurus Ab
  • Ceramisphere Pty Ltd.
  • Cytimmune Sciences
  • Glaxosmithkline Plc.
  • Hoffmann-La Roche Inc.

Nanoparticle technology has made major advances in particle type, production, and application in all areas of the life sciences in the past two decades. The most rapid advances have been made in the application of nanoparticles in drug research and development, drug product formulation, and development of novel drug delivery systems using nanoparticle carriers. The development of nanoparticles and their rapid incorporation into the research and development, formulation, and production of drug products has given rise to a new area of biotechnology and pharmaceutical research involving particle materials in the nanometer size range.

Nanoparticles used in the life sciences and biomedical applications are usually considered to be in the range of 10 nanometers to 100 nanometers in diameter. Developing particles from various starting materials that remain stable in this size range has become one of the fastest-growing and most potentially useful emerging technologies of the last several decades.

Both particle size and shape are important in the life sciences because the particle properties of biopharmaceutical products can impact a drug product in two ways: size and shape. Size and shape can have an influence on drug performance or efficacy in the body.

The methods for producing nanoparticles vary depending on the starting substrate materials and the size particle desired as a product. This report will provide an overview of various production methods and indicate new advances in the production area. At present, the U.S. holds the largest number of patents in the nanoparticle area. This is largely due to the early commercialization of some nanoparticle products by U.S. companies. It also reflects that the contribution to research and development of new ideas by American companies is larger than those by most other countries.

Europe is the second-largest market for nanoparticle drug technology. France, Germany, and the U.K. are the major contributors to its market share. Drug formulation and delivery are attracting new players in Europe, and this in turn will contribute to the market’s growth.

Note: Product cover images may vary from those shown
  • Bristol-Myers Squibb Co.
  • Camurus Ab
  • Ceramisphere Pty Ltd.
  • Cytimmune Sciences
  • Glaxosmithkline Plc.
  • Hoffmann-La Roche Inc.
  • Merck & Co. Inc.
  • Nanocarrier Co. Ltd.
  • Novartis Ag
Note: Product cover images may vary from those shown
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