Lanzkowsky's Manual of Pediatric Hematology and Oncology, Seventh Edition remains the go-to clinical manual for the treatment and management of childhood cancers and blood disorders. It is a comprehensive book on patient management, replete with algorithms and flow diagrams, and includes a new section on vascular anomalies. Reflecting the considerable advances in the treatment and management of hematologic and oncologic diseases in children, the seventh edition of this successful clinical manual is entirely updated to incorporate all current treatment protocols, new drugs, and management approaches. Its concise and easy-to-read format, again, enables readers to make accurate diagnoses and treatment decisions without having to reference larger medical textbooks.
- Designed to be easily readable and highly practical with over 400 illustrative tables, along with color diagrams and figures
- New chapter on Pediatric Vascular Anomalies
- New content on 'blood avoidance' programs to honor religious preferences
- Discussions of new drugs and immunological therapies for cancers, along with discussions of increasing use of cytokine stimulants for hematologic disorders
- Includes practical genetic evaluations providing a deeper understanding and advances in management of bone marrow failure diseases
1. Diagnostic Molecular and Genomic Methodologies for the Hematologist/Oncologist 2. Hematologic Manifestations of Systemic Illness 3. Classification and Diagnosis of Anemia in Children 4. Lymphadenopathy and Diseases of the Spleen 5. Anemia During the Neonatal Period 6. Iron-Deficiency Anemia 7. Megaloblastic Anemia 8. Bone Marrow Failure 9. General Considerations of Hemolytic Diseases, Red Cell Membrane, and Enzyme Defects 10. Extracorpuscular Hemolytic Anemia 11. Hemoglobinopathies 12. Polycythemia 13. Disorders of White Blood Cells 14. Disorders of Platelets 15. Disorders of Coagulation 16. Lymphoproliferative Disorders 17. Myelodysplastic Syndromes and Myeloproliferative Disorders 18. Acute Lymphoblastic Leukemia 19. Acute Myeloid Leukemia 20. Histiocytosis Syndromes 21. Hodgkin Lymphoma 22. Non-Hodgkin Lymphoma 23. Central Nervous System Malignancies 24. Neuroblastoma 25. Renal Tumors 26. Rhabdomyosarcoma and Other Soft-Tissue Sarcomas 27. Malignant Bone Tumors 28. Retinoblastoma 29. Germ Cell Tumors 30. Hepatic Tumors 31. Hematopoietic Stem Cell Transplantation 32. Management of Oncologic Emergencies 33. Supportive Care of Patients with Cancer 34. Evaluation, Investigations, and Management of Late Effects of Childhood Cancer 35. Psychosocial Aspects of Cancer for Children and Their Families 36. Blood Banking Principles and Practices
Appendix 1. Hematological Reference Values 2. Biological Tumor Markers
Jonathan D. Fish, MD is Assistant Professor of Pediatrics at the Hofstra Northwell School of Medicine. He is Director of the Survivors Facing Forward Program, a long-term follow-up program for survivors of childhood cancer, in the division of Pediatric Hematology/Oncology and Stem Cell Transplantation at the Steven and Alexandra Cohen Children's Medical Center of New York. He holds a B.A., with distinction, from the University of Western Ontario and received his M.D. degree, magna cum laude, from the Upstate Medical Center of the State University of New York. He did his Pediatric training at the the Schneider Children's Hospital, New Hyde Park, NY ( Presently known as the Steven and Alexandra Children's Medical Center of New York) and completed his Pediatric Hematology-Oncology fellowship training at the Children's Hospital of Philadelphia. Dr. Fish received the American Society of Pediatric Hematology-Oncology Young Investigator Award in 2008. His clinical and research interest is on the late effects of childhood cancer treatment and survivorship care.
Lipton, Jeffrey M.
Jeffrey M. Lipton, MD, PhD is the Chief of Hematology/Oncology and Stem Cell Transplantation at the Steven and Alexandra Cohen Children's Medical Center of New York and Center Head, Patient Oriented Research, The Feinstein Institute for Medical Research. He is Professor, Elmezzi Graduate School of Molecular Medicine, The Feinstein Institute for Medical Research and Professor of Pediatrics and Molecular Medicine at the Hofstra North Shore - LIJ School of Medicine. He holds a B.A. from Queens College, City University of New York, a Ph.D in Chemistry from Syracuse University and an M.D. degree, magna cum laude, from Saint Louis University Medical School. He did his Pediatric residency training at the Children's Hospital, Boston, MA and his Pediatric Hematology/Oncology fellowship training at the Children's Hospital and the Sidney Farber Cancer Institute (now DFCI) in Boston. Dr. Lipton is a Past-President of the American Society of Pediatric Hematology/Oncology (ASPHO). His main interest is bone marrow failure.
Dr. Philip Lanzkowsky was born in Cape Town on March 17, 1932 and graduated high school from the South African College and obtained his MB ChB degree from the University of Cape Town School of Medicine in 1954 and his Doctorate degree in 1959 for his thesis on Iron Deficiency Anemia In Children. He completed a pediatric residency at the Red Cross War Memorial Children's Hospital in Cape Town in 1960. After working in Pediatrics at the University of Edinburgh and at St Mary's Hospital of the University of London, Dr. Lanzkowsky did a pediatric Hematology-Oncology fellowship at Duke University School of Medicine and at the University of Utah.
In 1963 he was appointed Consultant Pediatrician and Pediatric Hematologist to the Red Cross War Memorial Children's Hospital at the University of Cape Town and introduced Pediatric Hematology and Oncology as a distinct discipline. In 1965 he was appointed Director of Pediatric Hematology and Associate Professor of Pediatrics at the New York Hospital-Cornell University School of Medicine.
In 1970 he was appointed Professor of Pediatrics and Chairman of Pediatrics at Long Island Jewish Medical Center and established a division of Pediatric Hematology-Oncology which he directed until 2000. He was the founder of the Schneider Children's Hospital, which he developed, planned, and was the hospital's Executive Director and Chief of Staff from its inception in 1983 until 2010.
Dr. Lanzkowsky has received numerous honors and awards and has lectured extensively at various institutions and medical schools in the United States and around the world. In addition to having been the author of five editions of the Manual of Pediatric Hematology and Oncology used by clinicians worldwide, he is the author of How It All Began: The History of a Children's Hospital and over 280 scientific papers, abstracts, monographs, and book chapters.
Dr. Lanzkowsky's medical writings have been prodigious. His seminal contributions to the medical literature have included the first description of the relationship of pica to iron-deficiency anemia (Arch. Dis Child., 1959), Effects of timing of clamping of umbilical cord on infant's hemoglobin level (Br. Med. J., 1960), Normal oral D-xylose test values in children (New Engl. J. Med., 1963), Normal coagulation factors in women in labor and in the newborn (Thromboses at Diath. Hemorr., 1966), Erythrocyte abnormalities induced by malnutrition (Br. J. Haemat., 1967), Radiologic features in iron deficiency anemia (Am. J. Dis. Child., 1968), Isolated defect of folic acid absorption associated with mental retardation (Blood, 1969; Am. J. Med, 1970), Disaccharidase levels in iron deficiency (J. Pediat., 1981) and Hexokinase "New Hyde Park in a Chinese kindred (Am. J. Hematol., 1981).