Lanzkowsky's Manual of Pediatric Hematology and Oncology, Seventh Edition remains the go-to clinical manual for the treatment and management of childhood cancers and blood disorders. It is a comprehensive book on patient management, replete with algorithms and flow diagrams, and includes a new section on vascular anomalies. Reflecting the considerable advances in the treatment and management of hematologic and oncologic diseases in children, the seventh edition of this successful clinical manual is entirely updated to incorporate all current treatment protocols, new drugs, and management approaches. Its concise and easy-to-read format, again, enables readers to make accurate diagnoses and treatment decisions without having to reference larger medical textbooks.
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Table of Contents1. Molecular and genomic methodologies for clinicians
2. Hematologic manifestations of systemic illness
3. Classification and diagnosis of anemia in children and neonates
4. Nutritional anemias
5. Lymphadenopathy and diseases of the spleen
6. Bone marrow failure
7. General considerations of hemolytic diseases, red cell membrane, and enzyme defects
8. Extracorpuscular hemolytic anemia
10. Primary and secondary erythrocytosis
11. Disorders of white blood cells
12. Disorders of platelets
13. Disorders of coagulation
14. Vascular anomalies
15. Histiocytic disorders
16. Lymphoproliferative disorders
17. Myelodysplastic syndromes and myeloproliferative disorders
18. Acute lymphoblastic leukemia
19. Acute myeloid leukemia
20. Hodgkin lymphoma
21. Non-Hodgkin lymphoma
22. Central nervous system tumors
24. Renal tumors
25. Rhabdomyosarcoma and other soft-tissue sarcomas
26. Malignant bone tumors
28. Extracranial germ cell tumors
29. Hepatic tumors
30. Hematopoietic stem cell transplant and cellular therapy
31. Management of oncologic emergencies
32. Supportive care of patients with cancer
33. Evaluation, investigations, and management of late effects of childhood cancer
34. Psychosocial factors impacting children with cancer and their families
35. Pediatric blood banking principles and transfusion medicine practices
AuthorsJonathan D. Fish Assistant Professor of Pediatrics, Hofstra Northwell School of Medicine, Hempstead, NY, USA. Jonathan D. Fish, MD is Assistant Professor of Pediatrics at the Hofstra Northwell School of Medicine. He is Director of the Survivors Facing Forward Program, a long-term follow-up program for survivors of childhood cancer, in the division of Pediatric Hematology/Oncology and Stem Cell Transplantation at the Steven and Alexandra Cohen Children's Medical Center of New York. He holds a B.A., with distinction, from the University of Western Ontario and received his M.D. degree, magna cum laude, from the Upstate Medical Center of the State University of New York. He did his Pediatric training at the the Schneider Children's Hospital, New Hyde Park, NY ( Presently known as the Steven and Alexandra Children's Medical Center of New York) and completed his Pediatric Hematology-Oncology fellowship training at the Children's Hospital of Philadelphia. Dr. Fish received the American Society of Pediatric Hematology-Oncology Young Investigator Award in 2008. His clinical and research interest is on the late effects of childhood cancer treatment and survivorship care. Jeffrey M. Lipton Professor of Pediatrics and Molecular Medicine, Hofstra North Shore-LIJ School of Medicine, Hempstead, NY, USA. Jeffrey M. Lipton, MD, PhD is the Chief of Hematology/Oncology and Stem Cell Transplantation at the Steven and Alexandra Cohen Children's Medical Center of New York and Center Head, Patient Oriented Research, The Feinstein Institute for Medical Research. He is Professor, Elmezzi Graduate School of Molecular Medicine, The Feinstein Institute for Medical Research and Professor of Pediatrics and Molecular Medicine at the Hofstra North Shore - LIJ School of Medicine. He holds a B.A. from Queens College, City University of New York, a Ph.D in Chemistry from Syracuse University and an M.D. degree, magna cum laude, from Saint Louis University Medical School. He did his Pediatric residency training at the Children's Hospital, Boston, MA and his Pediatric Hematology/Oncology fellowship training at the Children's Hospital and the Sidney Farber Cancer Institute (now DFCI) in Boston. Dr. Lipton is a Past-President of the American Society of Pediatric Hematology/Oncology (ASPHO). His main interest is bone marrow failure. Philip Lanzkowsky North Shore-Long Island Jewish Health System, Consultant, Steven and Alexandra Cohen Children's Medical Center of New York, Professor of Pediatrics, Hofstra Northwell School of Medicine, Hempstead, NY, USA. Dr. Philip Lanzkowsky was born in Cape Town on March 17, 1932 and graduated high school from the South African College and obtained his MB ChB degree from the University of Cape Town School of Medicine in 1954 and his Doctorate degree in 1959 for his thesis on Iron Deficiency Anemia In Children. He completed a pediatric residency at the Red Cross War Memorial Children's Hospital in Cape Town in 1960. After working in Pediatrics at the University of Edinburgh and at St Mary's Hospital of the University of London, Dr. Lanzkowsky did a pediatric Hematology-Oncology fellowship at Duke University School of Medicine and at the University of Utah.
In 1963 he was appointed Consultant Pediatrician and Pediatric Hematologist to the Red Cross War Memorial Children's Hospital at the University of Cape Town and introduced Pediatric Hematology and Oncology as a distinct discipline. In 1965 he was appointed Director of Pediatric Hematology and Associate Professor of Pediatrics at the New York Hospital-Cornell University School of Medicine.
In 1970 he was appointed Professor of Pediatrics and Chairman of Pediatrics at Long Island Jewish Medical Center and established a division of Pediatric Hematology-Oncology which he directed until 2000. He was the founder of the Schneider Children's Hospital, which he developed, planned, and was the hospital's Executive Director and Chief of Staff from its inception in 1983 until 2010.
Dr. Lanzkowsky has received numerous honors and awards and has lectured extensively at various institutions and medical schools in the United States and around the world. In addition to having been the author of five editions of the Manual of Pediatric Hematology and Oncology used by clinicians worldwide, he is the author of How It All Began: The History of a Children's Hospital and over 280 scientific papers, abstracts, monographs, and book chapters.
Dr. Lanzkowsky's medical writings have been prodigious. His seminal contributions to the medical literature have included the first description of the relationship of pica to iron-deficiency anemia (Arch. Dis Child., 1959), Effects of timing of clamping of umbilical cord on infant's hemoglobin level (Br. Med. J., 1960), Normal oral D-xylose test values in children (New Engl. J. Med., 1963), Normal coagulation factors in women in labor and in the newborn (Thromboses at Diath. Hemorr., 1966), Erythrocyte abnormalities induced by malnutrition (Br. J. Haemat., 1967), Radiologic features in iron deficiency anemia (Am. J. Dis. Child., 1968), Isolated defect of folic acid absorption associated with mental retardation (Blood, 1969; Am. J. Med, 1970), Disaccharidase levels in iron deficiency (J. Pediat., 1981) and Hexokinase "New Hyde Park in a Chinese kindred (Am. J. Hematol., 1981).