Nanocarriers for the Delivery of Combination Drugs focuses on the role of nanocarriers in the delivery of combination drugs for the management and treatment of various diseases. Nanocarriers belonging to the category of polymeric nanoparticles, dendrimers, lipidic nanocarriers (like nanoemulsions), liposomes, solid lipid nanoparticles, nanostructured lipid carriers are now being used in the drug delivery of combination drugs. This book helps readers assimilate all the information available surrounding the application of various nanocarrier technologies for the delivery of combination drugs of synthetic and natural origin, including small and large molecules.
This is an important reference source for pharmaceutical scientists and biomaterials scientists who are looking to gain an increased understanding on how nanotechnology is improving the efficiency of combination drug delivery.
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Table of Contents
1. Combination drug delivery: Past, present and future 2. Application of nanocarrier approach for the delivery of combination drugs 3. Polymeric nanocarriers for delivery of combination drugs 4. Liposomal nanocarriers for delivery of combination drugs 5. Lipidic nanocariers for delivery of combination drugs 6. Nanocarriers as an effective drug delivery approach for combination drugs for treatment of cancer 7. Nanocarriers as an effective drug delivery approach for combination drugs for treatment of neurodegenerative disorders 8. Nanocarriers as an effective drug delivery approach for combination drugs for treatment of various topical skin disorders 9. Nanocarrier based formulations of combination drugs with focus on Phytoconstituents 10. Nanocarriers in delivery of combination drugs: Challenges and future aspects
Authors
Sanjula Baboota Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India. Prof. Sanjula Baboota passed her Bachelors and Masters in Pharmacy with distinction from the School of Pharmaceutical Education and Research, Jamia Hamdard in 1993 and 1995 respectively. She was a gold medallist in her post graduate programme. She earned her Ph. D. in the year 2002 from Jamia Hamdard. She is presently working as Professor at Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard. She has a total experience of about 25 years in teaching, research and mentoring.Prof. Sanjula teaches at undergraduate, post graduate and doctoral levels and has also prepared e-content for postgraduate students on subjects like biopharmaceutics and cosmetics. Her research interests include improving oral bioavailability of BCS class II and Class IV drugs using approaches like complexation, polymeric conjugates, lipid based systems like microemulsions, nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers. She is actively involved in formulating nanoparticulate drug delivery systems for treatment of neurological disorders and cancer. Recently the research group of Prof. Baboota has expanded their research on formulating nanocarriers of combination drugs as combination drug therapy provides additive or synergistic effect, increases the spectrum of treatment, reduces the side effects, helps in overcoming the resistance, improves patient compliance and targets multiple pathways taking part in disease progression. Encapsulation of combination drugs in nanocarriers helps in overcoming the various biopharmaceutical challenges associated with the them thereby creating opportunities for better treatment.
Prof Baboota is actively engaged in supervising post graduate and doctoral research work. More than 65 theses at post graduate level and 30 doctoral research work is being guided by her. Her research work has received financial supports from all the leading sponsoring bodies in India. She has published more than 300 papers which includes original research articles, review articles, proceedings and invited book chapters in edited books in the field of drug delivery. The work has also been presented at various national and international conferences. She has written several textbooks and has contributed chapters in books on controlled and novel drug delivery systems. Prof. Baboota research work has received more than 10886 citations and she is having an h-index of 53 and i10 index of 152 as per the June 2021 Google Scholar data.
Prof. Baboota has guest edited thematic issues for internationally reputed journals and also serves as regional editor and editorial board member for several international journals. She is a referee for a number of referred journal of repute and also a reviewer for book proposals of reputed international publishers. She serves as an expert for evaluation of national and international projects of different universities and funding bodies. She is also on examination panel of a number of University both in India and abroad for Ph.D theses evaluation.
Prof. Baboota has been bestowed with several honours, a few of them worth mentioning include the research award by UGC, Young Pharmacy teacher of the year award by APTI, Dr. P.D.Sethi research paper annual award for her research paper and several other best paper presentation awards. She has also received certificate of recognition for publication in high impact factor journals and citations from Jamia Hamdard. Prof. Baboota featured in the top scientists in 2019 global list across all fields as per the data released by Stanford University and was awarded level 5 certificate in management and leadership by Chartered management Institute (CMI), United Kingdom.
Prof. Baboota her shared her research and teaching experience in several conferences, seminars, symposiums and workshops as a chairperson and invited speaker. She is also actively engaged in various committees of the department, school and University. She is a member/Life member of several Indian and international scientific organizations. Javed Ali Professor, Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India. Prof. Javed Ali passed his BPharm and MPharm with distinction from Jamia Hamdard and bagged gold medals in 1994 and 1996, respectively. He earned a PhD in the year 2000. He was a postdoctoral fellow at the Institute of Pharmaceutical Technology, University of Frankfurt, Germany in 2005. He has a total experience of 25 years in teaching and research. Presently, he is working as a professor at the Department of Pharmaceutics, School of Pharmaceutical Education and Research, and is in-charge of IP Management Cell, Jamia Hamdard, New Delhi.
Prof. Ali has been bestowed with several honors; a few of them worth mentioning include the Career Award for Young Teachers by All India Council of Technical Education (2003); APTI-Young Pharmacy Teacher of the year (2004) by Association of Pharmacy Teachers of India; the BOYSCAST Fellowship of Department of Science and Technology, Government of India (2005); American Association of Indian Pharmaceutical Scientists (AAiPS)-IPA Distinguished Educator and Researcher Award 2007 at the Association meeting at San Diego, United States; Research Award 2014 by University Grants Commission, New Delhi; and Indian National Science Academy (INSA) Teachers Award 2018 by INSA, New Delhi for his outstanding teaching methodology and research outputs; in addition, several awards for best paper presentations at conferences of Indian Pharmaceutical Congress, Indian Pharmacy Graduate Association, and Controlled Release Society, Indian Chapter. He has also received certificates of recognition for publications in high-impact factor journals from Jamia Hamdard.
Prof. Ali has received research grants from a large number of agencies including FIP (the Netherlands) and industries. He is actively involved in the field of drug delivery, which includes improvement in oral bioavailability of BCS classes II and IV drugs by polymeric conjugates and nanolipid-based systems and nanoparticulate drug delivery systems for brain delivery. He is supervising scientific research at the postgraduation and the doctoral level. He has guided 76 theses of MPharm and 37 theses of PhD. Presently, 12 PhD theses are under his supervision. He is an external expert for PhD theses of a large number of Indian and foreign universities. He has written several books and has contributed several chapters in books on controlled and novel drug delivery systems of reputed Indian and international publishers. A widely traveled person, he has presented his research work in more than 100 conferences held in India and abroad. He has a list of about 350 manuscripts in journals of repute and five Indian patents granted/applied. He has an h-index of 65, i10 index of 242, and more than 17,000 citations to his credit as per Google Scholar bibliometric data in June, 2021. He has been named in the list of top 2% worldwide scientists in the field of pharmacy and pharmacology and also named in the top scientists in 2019 global list across all fields by a publication of Stanford University in 2019. He has also worked as a paper coordinator of UGC ePathshala project of the Ministry of Education, Government of India, for two papers of pharmaceutical sciences. He is a reviewer to a large number of international and national journals of repute and book proposals from various international publishers. He is an expert for projects review for agencies of various countries. He is on the editorial board of many renowned journals.
Prof. Ali is also actively engaged in committees of various universities/councils/ accreditation bodies/public service commissions, etc. He has been an executive member of the Indian Pharmaceutical Association (Delhi Branch) from 2012 to date. He has been a member of the local organizing scientific committees of conferences. He has been delivering talks on various topics on regulatory affairs in national and international conferences/workshops and for various undergraduate and post-graduate courses. He is a resource person and has organized staff development/ refresher/short-term training programs from time to time. He is a member/life member of 20 Indian and international scientific organizations.
