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Tailor-Made and Functionalized Biopolymer Systems. Woodhead Publishing Series in Biomaterials

  • ID: 5230548
  • Book
  • June 2021
  • 690 Pages
  • Elsevier Science and Technology
Tailor-Made and Functionalized Biopolymer Systems: For Drug Delivery and Biomedical Applications covers the design and application of these functionalized and tailor-made biopolymers and biopolymer systems intended for drug delivery and biomedical applications. Various concepts, design protocols and biomedical applications of tailor-made biopolymer systems are covered, guiding the reader from theoretical knowledge to practical application. Authored by an array of experts from global institutions, this book offers an interdisciplinary approach to how tailor-made biopolymers lead to novel drug delivery and treatment solutions. This will be a useful reference to a broad audience, including biomedical engineers, materials scientists, pharmacologists and chemists.
  • Provides a concise overview of tailor-made and functionalized biopolymer systems for biomedical applications
  • Covers a range of modified biopolymers, biopolymeric composites and biopolymer-based systems in drug delivery, development of artificial organs, diagnostic applications, and more
  • Describes characterization, synthesis and functionalization of biopolymers and biopolymers systems
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1. Introduction

Section 1: Modified biopolymers 2. Thiolated biopolymers in drug delivery and biomedical applications 3. Smart biopolymers for controlled drug delivery applications 4. Alginate based systems for protein and peptide delivery 5. Chitosan based polyelectrolyte complexes in biomedical applications 6. Tailor-made cyclodextrin based nanomaterials as drug carriers

Section 2: Biopolymeric conjugates/composites 7. Biopolymer-metal oxide composites in biomedical applications 8. Biopolymer-drug conjugates as biomaterials 9. Functionalized biopolymer-clay based composites as drug-cargos 10. Mesoprous silica-biopolymer based systems in drug delivery applications

Section 3: Modified biopolymer based biomaterials 11. Micellar drug delivery systems based on amphiphilic block and graft biopolymers 12. Engineering of biopolymer based nanofibers for medical use 13. Engineered protein and protein-polysaccharide cages for drug delivery and therapeutic applications 14. Biopolymer-lipid based systems in biomedical applications 15. Biopolymeric hydrogels prepared via click chemistry as carriers of therapeutic modalities 16. Biopolymeric nanocrystals in drug delivery applications

Section 4: Biopolymeric systems in biomedical applications 17. Functionalized biopolymers for colon targeted drug delivery 18. Modified biopolymer-based hydrogels for localized drug delivery to brain 19. Modified biopolymers based chronotherapeutic drug delivery systems 20. Biopolymeric systems for the delivery of nucleic acids (gene, siRNA, miRNA etc.) 21. Stimuli responsive biopolymeric systems for drug delivery to cancer cells 22. Stimuli responsive biopolymeric systems in the development of smart artificial organs and medical devices 23. Biopolymeric systems for diagnostic applications 24. Conclusion

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Bera, Hriday
Dr. Hriday Bera completed his Masters study at Jadavpur University, Kolkata, India and Ph.D at National University of Singapore, Singapore. He is presently working as Post-doctoral Fellow at Shenyang Pharmaceutical University, China and Nano Medical Engineering Laboratory, RIKEN, Wako, Japan. The major focus of his current research is the conceptual design, fabrication and evaluation of chemically modified naturally-occurring polymer based systems intended for drug delivery and other biomedical applications. As a part of his research career, he published 36 peer-reviewed articles (including 23 first-author articles) in various international journals of repute with a total SCI citation of 546, h-index of 15 and i10-index of 20. Moreover, he penned 20 book chapters for various international publishers. Furthermore, as a principal investigator, he has received highly competitive research grants from AICTE, Govt. of India; Ministry of Higher Education, Govt. of Malaysia; National Natural Science Foundation, China and Tekada Science Foundation, Japan.
Layek, Buddhadev
Dr. Buddhadev Layek received his Master of Pharmacy degreefrom Jadavpur University in Kolkata, India and Ph.D. in Pharmaceutical Sciences from North Dakota State University in Fargo, USA. He is currently working as a Postdoctoral Researcher at the University of Minnesota in Minneapolis, USA. His primary research interests include tumor-targeted drug delivery, modulating the tumor microenvironment to improve outcomes of cancer therapy, and designing multifunctional, polymeric nanomaterials for drug andgene delivery. Layek has published 22 peer-reviewed articles in high impact journals and 6 book chapters for various international publishers. He has also served as a guest editor for special issues on "Cell-Penetrating Peptides” and "Surface-Functionalized Nanoparticles as Drug Carriers” in the International Journal of Molecular Sciences.
Singh, Jagdish
Dr. Singh is Professor and Chair of the Department of Pharmaceutical Sciences at NDSU School of Pharmacy, and a Fellow of American Association of Pharmaceutical Scientists (AAPS) and Fellow, Association of Biotechnology and Pharmacy. Dr. Singh's research efforts focus on the mechanistic studies for developing and testing novel delivery technologies to deliver biotechnologically derived molecules (e.g., peptide, protein, and gene), using smart polymers, nanomicelles and nanoparticles for the prevention and treatment of neurodegenerative diseases, other brain disorders, and diabetes. National Institutes of Health, US Department of Defense, PhRMA Foundation, and AFPE have funded Dr. Singh's research. Dr. Singh has published over 175 peer-reviewed papers and 350 abstracts.
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