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Cell-Based Liver Regeneration. Current Aspects and Future Approaches

  • Book

  • December 2023
  • Elsevier Science and Technology
  • ID: 5238317
Stem cell therapy is a fast-growing field of medicine with remarkable prospects in a broad spectrum of diseases. Cell-Based Liver Regeneration: Current Aspects and Future Approaches addresses the full spectrum of regenerative medicine in liver diseases. Coverage will include the basic science, current research and a comprehensive review of clinical trials conducted in the field.The book will discuss the various types of stem cells for liver regeneration, presenting the advantages and disadvantages of each type. A review of all aspects of implanting stem cell therapy for the liver, such as: choosing the cell type, the source, laboratory manipulation, dose, route and follow-up. The book concludes with a full discussion of the current clinical trials involving cellular therapy in liver regeneration.Cell-Based Liver Regeneration: Current Aspects and Future Approaches is written for stem cell biologists, liver biologists, hepatologists and graduate students by authors with extensive knowledge in basic, pre-clinical and clinical stem cell research.

Table of Contents

Part 1: BiologyIntroduction1. Tips from EmbryologyWael Abo El-Kheir and Hala Gabr2. From Embryology to Histology: Cells, Tracts and moreWael Abo El-Kheir and Hala Gabr3. Physiology of the LiverWael Abo El-Kheir and Hala GabrPart 2: Regeneration4. Physiology of liver regenerationWael Abo El-Kheir and Hala Gabr5. Pathological alterations in liver regenerationWael Abo El-Kheir and Hala GabrPart 3: Cellular Therapy6. Cellular Therapy of Liver disease: Theory and Pre-clinical experimentsWael Abo El-Kheir and Hala Gabr7. Cellular Therapy of Liver Disease: Laboratory issues

Authors

Hala M. Gabr Professor of Hematology, Department of Clinical Pathology, Cairo University, Egypt. Dr. Gabr is a Professor of Hematology in the Department of Clinical Pathology at Cairo University, in Egypt. She received her Doctor's Degree in Clinical and Chemical Pathology in 1995 from Cairo University, where she also received her Bachelor, Master's and completed her residency. Dr. Gabr's subspecialty is tissue culture, cytogenetics and stem cell biology and she has published 27 papers in international journals. Dr. Gabr is member of the International Society for Hematology and Stem Cells "ISEH", a member of the European Society for Gene and Cell Therapy (ESGCT), a council member of the International Federation of Neurorestoratology, a scientific advisor of the "Egyptian Foundation of Molecular Biology", a scientific advisor of the "Egyptian Society for Progenitor Cell Research", a member of the Egyptian society of Laboratory medicine, a member of the Egyptian society of Hematology & Research and a reviewer for the European Journal of Gastroenterology and Hepatology. Wael Abo El-Kheir Vice President, Founder and Board Member, Egyptian Society for Progenitor Stem Cell Research, Cairo, Egypt. Wael Abo Elkheir completed his PhD from Cairo University, Egypt. He is the Vice President, Founder and Board Member of the Egyptian Society for Progenitor Stem Cell Research (ESPCR), a society initiated with the mission of enhancing scientific research and cooperation in the field of stem cell research and regenerative medicine. Dr. Elkheir is the Director of a number of registered clinical trials in the field of stem cell therapy, especially for neuro-regeneration and musculoskeletal disorders. He has published more than 20 papers in reputed journals. He is member of the International Society for Cellular Therapy (ISCT), a member of the National Stem Cell Committee, laboratory consultant of the Al-Azhar University Stem Cell Therapy for Spinal Cord Injury Project, laboratory consultant of the National Institute for Cardiology Project for Stem Cell Therapy and scientific advisor of the "Egyptian Foundation of Molecular Biology".