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Biologically Active Natural Products from Asia and Africa: A Selection of Topics

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    Book

  • January 2021
  • Region: Africa, Asia Pacific
  • Bentham Science Publishers Ltd
  • ID: 5241691

Both Asia and Africa are home to many plants that can be used for the treatment of many diseases and their medicinal properties are gaining interest in western societies. Medicinal plants from Asia and Africa are used for their healing abilities and also have a symbolic meaning in communities. The importance of traditional autochthonous plant remedies plays a crucial role in the health of millions of people of these two continents. Even today, traditional medicine represents the dominant medical system for millions of people showing a significant impact on health care practices. 

Therefore, traditional operators still represent a vital part of regional healthcare systems. For this reason, pharmaceutical industries consider traditional medicine as a source for the identification of bioactive compounds that can be used in the preparation of synthetic drugs. Biologically Active Natural Products from Asia and Africa: A Selection of Topics guides the reader toinformation about new natural products from these regions and the different ways to use them to treat or alleviate many of the most common diseases. 

The volume presents nine topics covering a number of facets of natural product medicine including:


  • Pharmaceutical analysis of anti
  • Diabetic herbal medicines from Bangladesh and local retailers
  • Caffeine intake and the risk of female infertility
  • Pharmaceutical analysis of Urena sinuata (bur mallow)
  • Anti-CHIKV activities of diterpenes and their derivatives
  • Anti-inflammatory nanogel for the treatment of psoriasis
  • Antlithiatic properties of Moroccan medicinal plants
  • Ethnobotanic, phytochemical and biological activities of Aristolochia longa L. (pipevine)
  • Wound healing potential of combined extracts of stem bark and leaves of sphenocentrum jollyanum (an African shrub).

This is a handy reference for specialists and R&D experts in pharmaceutical chemistry who wish to be informed about Current knowledge on developing natural remedies in Asia and Africa.


Table of Contents

Chapter 1 Biological and Physical Contaminants in Anti-Diabetic


  • Herbal Medicines of Bangladesh
  • Rausan Zamir, Nazmul Islam, Sunzid Ahmed, Md. Ali Asraf, Nikhil C. Bhoumik,
  • Omar Faruque and Akhter Farooque
  • Introduction
  • Methods
  • Study Area and Sample Collection
  • Determination of Ph
  • Microbiological Analysis
  • Preparation of Culture Media
  • Isolation and Identification of Microorganisms
  • Total Aerobic Bacterial Count and Total Coliform Count
  • Escherichia Coli 0157
  • Escherichia Coli
  • Salmonella Spp.
  • Listeria Spp.
  • Yeasts and Molds Count (Ymc)
  • Toxic Metal Analysis
  • Results
  • Microbial Contamination
  • Metal Toxicity
  • Discussion
  • Biological Contamination (Microbes)
  • Physical Contamination (Metal Toxicity)
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 2 Quantification and Health Safety Assessment of Some Toxic


  • Metals in Anti-Diabetic Herbal Preparations Collected
  • From Local Retailers Using the Xrf Analytical Tool
  • Rausan Zamir, Nazmul Islam, Mahfuza Parveen, Shipra Sarker, Rajib Kanti,
  • M. Safiur Rahman and Omar Faruque
  • Introduction
  • Methods
  • Study Area and Sample Collection
  • Sample Preparation and Analysis
  • Results and Discussion
  • Conclusion
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References
  • A. Zaifar, E.N. Nabila, L.D. Vincent, N.M.P Kusuma, S.S.K. Nareswari and M. Louisa
  • Case
  • Introduction
  • Methods
  • Results
  • Discussion
  • Conclusion
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 3 Caffeine Intake and the Risk of Female Primary Infertility: An Evidence-Based Case Report


  • Materials and Methods
  • Collection of Plant Material
  • Extraction of Plant Material
  • Formulations of Nanogel
  • Preparation of Drug-Loaded Nanodispersions
  • Preparation of Nanogel
  • Evaluation of Developed Formulation
  • Appearance
  • Determination of Ph
  • Determination of Homogeneity
  • Viscosity
  • Particle Size
  • Spreadability
  • Skin Irritancy Test
  • Results and Discussion
  • Particle Size Determination
  • Zeta Potential Measurements
  • Stability Studies
  • In-Vivo Anti-Inflammatory Activity
  • Animals
  • Carrageenan-Induced Mice Paw Oedema Method
  • Statistical Analysis
  • Results and Discussion
  • Discussion and Conclusion
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 4 an Overview of Urena Sinuata: Phytochemistry and Pharmacological Activities


  • Pranta Ray, Rajib Hossain, Md. Matiur Rahman and Muhammad Torequl Islam
  • Introduction
  • Research Methodology
  • Findings
  • Phytochemicals of U. Sinuata
  • Pharmacological Activities of U. Sinuata
  • Antioxidant Activity
  • Anti-Diarrhoeal Activity
  • Anti-Nociceptive Activity
  • Anti-Inflammatory Activity
  • Anti-Pyretic Activity
  • Insecticidal and Insect-Repellent Activities
  • Thrombolytic Activity
  • Sedative, Anxiolytic, and Analgesic Activities
  • Toxicological Profile
  • Discussion
  • Summary and Perspectives
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 5 Anti-Chikv Activities of Diterpenes and Their Derivatives


  • Muhammad Torequl Islam
  • Introduction
  • Search Strategy
  • Findings
  • Conclusion and Future Perspectives
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 6 Design Development and Evaluation of Anti-Inflammatory


  • A.A. Yelmate, P. Gundewar and R.S. Moon
  • Introduction
  • Nanogel for the Treatment of Psoriasis

Chapter 7 Antilithiatic Properties of Moroccan Medicinal Plants and Mechanism Insights of Their Phytochemicals


  • Aya Khouchlaa, Abdelhakim Bouyahya and M'hamed Tijane
  • Introduction
  • Methods
  • Results and Discussion
  • Ethnobotany of Antilithiasic Medicinal Plants Used in Morocco
  • Experimental Methods to Evaluate the Antilithiatic Activity
  • In Vitro Methods
  • In Vivo Methods
  • Antilithiatic Mechanism of Phytomolecules
  • Changing Urine Parameters
  • Diuretic
  • Influence on the Crystallization Process
  • Cell Surface Adhesion
  • Antioxidant Effect
  • Conclusion
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 8 Ethnobotanic, Phytochemical, and Biological Activities of Aristolochia Longa L.: a Review


  • Amina El Yahyaoui El Idrissi, Aya Khouchlaa, Abdelhakim Bouyahya, Mereym El
  • Fessikh, Youssef Bakri and M'hamed Tijane
  • Introduction
  • Classification and Botanical Description
  • Ethnomedicobothany
  • Phytochemistry of A. Longa
  • Major Compounds, Including Phenols, Flavonoids, Alkaloids, Saponins
  • Fatty Acid Composition
  • Pharmacological and Biological Activities of A. Longa
  • Compounds
  • Anti-Tumor Activities
  • Antibacterial and Antifungal Activities
  • Antidiabetic Activities
  • Antioxidant Activities
  • Anti-Inflammatory Activities
  • Immunostimulatory Activities
  • Toxicity Effect
  • Conclusion
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 9 Wound Healing Potential of Combined Extracts of Stem Bark and Leaves of Sphenocentrum Jollyanum: a Classical Factorial Design Model Approach


  • Charles O. Nnadi, Chinwe M. Onah, Chigozie L. Ugwu and Wilfred O. Obonga
  • Introduction
  • Materials and Methods
  • Collection and Processing of Plant Materials
  • Preparation of the Plant Extracts
  • Phytochemical Analysis of Plant Extracts
  • Experimental Animals and Test Groups
  • Surgical Infliction of Excision Wound
  • Wound Treatment
  • Data Collection and Analysis
  • Statistical Analysis
  • Results
  • Phytochemical Constituents of Plant Extracts
  • Wound Closure Effects of Plant Extracts
  • Effects of Combined Extracts on Wound Healing Activities
  • Wound Surface Ph Profile
  • Discussion
  • Conclusion
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References
  • Subject Index

Author

  • Anna Capasso