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Mitochondrial Physiology and Vegetal Molecules. Therapeutic Potential of Natural Compounds on Mitochondrial Health

  • Book

  • July 2021
  • Elsevier Science and Technology
  • ID: 5315173

Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health provides a comprehensive overview of mitochondrial physiology throughout the human life span, as well as the effect of molecules of vegetal origin on mitochondrial health. The editor has lined up a team of worldwide experts to cover the most exciting and high-impact advancements of research in this area.

This book is structured into two parts that provide a balance of both foundational and applied content. Part I provides an overview of mitochondrial physiology including its structure, dynamics, biogenesis, membranes, DNA transcription, and translation in the mitochondria. Part I also covers other themes such as apoptosis. Part II then covers the effect of specific vegetable-derived molecules on mitochondrial health, including anthocyanins, caffeine, cannabinoids, carnosic and rosmarinic acids, citrus flavonoids, polyphenols, pterostilbene, resveratrol, and sulforaphane, among others.

Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health is a complete resource for researchers in this exciting field. Its comprehensive coverage makes it particularly interesting to bioscience researchers willing to understand the foundations of mitochondrial physiology throughout the human life span. Clinician researchers, MDs, nutritionists, pharmacologists, and sports scientists may be attracted to the detailed information on the health effects of vegetal origin molecules on the organelle.

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Table of Contents

Part I Overview of Mitochondrial Physiology

1. Mitochondria: Ultrastructure, Dynamics, Biogenesis and Main Functions

2. Mitochondrial biogenesis and mitophagy

3. DNA transcription and translation in the mitochondria

4. Mitochondrial redox biology: reactive species production and antioxidant defenses

5. Mitochondria and apoptosis

6. Mitochondria-Associated Membranes in the Maintenance of Cell Homeostasis

Part II The effects of plant molecules on the mitochondria in health and disease

7. Biopharmaceutical Properties of Natural Products

8. Carnosic acid and brain mitochondria

9. Rosmarinic acid and the mitochondria

10. The effects of sulforaphane on the mitochondria

11. Cannabinoids and mitochondria

12. Anthocyanins, effects in mitochondria and metabolism

13. Preclinical evidence of the therapeutic role of pterostilbene: focus on the mitochondria

14. Polyphenols attenuate mitochondrial dysfunction induced by amyloid peptides

15. Plant molecules to treat eye mitochondria

16. Mitochondria as a target for monoterpenes

17. Baccharis trimera phytochemicals and the mitochondria

18. Citrus flavonoids and the mitochondria

19. Caffeine and the brain mitochondria

20. Curcumin and the mitochondria

21. Catechins, neuroprotection and brain mitochondria

22. The effects of catechins on the cardiac mitochondria

23. Possible Roles of Garlic and Its Bioactive Components on Mitochondrial Function in Physiological and Pathological Conditions

24. Resveratrol effects on skeletal muscle mitochondria and contractile function

25. Antiaging effects of natural agents in the skin: focus on the mitochondria

26. Role of quercetin in the glial mitochondria: Implications for health and disease

27. The Therapeutic Effects of Lycopene on Mitochondrial Function in Human Diseases

28. Ascorbic acid and the mitochondria

29. Soy isoflavones, mitochondria, and cell fate

30. Resveratrol and the brain mitochondria

31. The role of plant molecules on the prevention and treatment of mitochondriarelated intoxication

32. Mitochondrial toxicity induced by plant molecules

33. Mitohormesis


Marcos Roberto de Oliveira Professor, Department of Biochemistry, Federal University of Rio Grande do Sul, Universidade Federal do Rio Grande do Sul (UFRGS), Instituto de Ci�ncias B�sicas da Saude (ICBS), Departamento de Bioqu�mica, Rua Ramiro Barcelos, Brazil. Dr Oliveira PhD earned his bachelor's degree in Biological Sciences at Federal University of Rio Grande do Sul (UFRGS) in 2005, followed by a Master's and a Ph.D. in Biochemistry from the same institution. His research focuses on the neuroprotection mediated by natural molecules and involves studies on mitochondrial physiology, redox biology, bioenergetics, and inflammation in both in vitro and in vivo experimental models.

Dr Oliveira has published numerous articles on peer-reviewed Journals, including Molecular Neurobiology, Chemico-Biological Interactions, Biotechnology Advances, and Oxidative Medicine and Cellular Longevity. He has also edited a book on the effects of plant molecules on the mitochondria Mitochondrial Physiology and Vegetal Molecules: Therapeutic Potential of Natural Compounds on Mitochondrial Health and a book on the role of mitochondrial dysfunction in both neurological disturbances and intoxication Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Related Strategies in Mitochondrial Medicine.