Advances in Non-coding RNAs in Cancer-Biology and Immunology covers the machinery of non-coding RNAs, including microRNA, LnRNA and piRNA, the identification of targets of these non-coding RNAs, and the identification of physiological and pathological roles of miRNAs, LnRNAs and piRNAs in immunology and cancer biology. The book introduces basic ideas of miRNAs, LnRNAs and piRNAs, along with detailed bio-processing steps, critical functions in the development of tumorigenesis and controlling immune cell responses, benefits for identifying different classes of non-coding RNAs and their targets, and finally, tactics on how to identify new members of these non-coding RNAs and predict possible functions.
In addition, the book captures the essence of the pioneering work of some of the world's leading researchers, showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs, LnRNAs and piRNAs, while also highlighting their potential towards the diagnosis and therapeutics of various diseases.
Table of Contents
1. The Machinery for MicroRNAs, LnRNAs and piRNAs2. MicroRNAs in cancer research
3. MicroRNAs in immunity
4. Advances of LnRNAs in cancer research
5. Advances of LnRNAs in immunity
6. Current view of piRNAs in cancer studies
7. Current view of piRNAs in immunity
8. MicroRNAs in diagnosis and therapeutics
9. LnRNAs as a tool for personalized therapy in cancers and immune-related diseases
10. piRNAs in the pathophysiology of disease and potential clinical applications