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Recent Developments in the Synthesis and Applications of Pyridines

  • Book
  • September 2022
  • Elsevier Science and Technology
  • ID: 5527391

Recent Developments in the Synthesis and Applications of Pyridines is a comprehensive handbook for organic chemists working on innovative approaches to the synthesis of pyridines. Written by scientists in both academia and industry and designed to be a standalone reference, the book features reviews, research results and case studies on synthetic methods and applications of pyridine-based chemotypes. The book will bridge the gap between industry and academia by presenting recent innovative approaches to the synthesis of pyridines, diverse application of pyridines in drug development, heterogeneous catalysis and material science, as well as benchtop to shelf narratives of pyridine-based compounds in the industry.

The role of computational chemistry in the development of pyridine-based bioactive molecules is also included. This reference is essential for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry.

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Table of Contents

1. Role of Pyridine and its Privileged Derivatives as Anti-infective agents
2. Pyridine-Based Polymers and Derivatives: Synthesis and Applications
3. Synthetic strategies of functionalized pyridines and their therapeutic potential as multifunctional anti-Alzheimer's agents
4. Design, synthesis and in vitro anticancer activity of thiophene substituted pyridine derivatives
5. The Role of Pyridine derivatives on the Treatment of Some Complex Diseases: A Review
6. Pyridines in Alzheimer's Disease Therapy: Recent Trends and Advancements
7. Pyridine derivatives as anti-Alzheimer agents
8. Role of Pyridines as Enzyme Inhibitors in Medicinal Chemistry
9. Contemporary development in the synthesis and biological applications of pyridine based heterocyclic motifs
10. Synthesis of Pyridine Derivatives using Multicomponent reactions
11. Recent Green Synthesis of Pyridines and their Fused Systems Catalyzed by Nanocatalysts
12. Pyridines as Anticancer Agents
13. Recent Developments in the Synthesis of Pyridine Analogues as a Potent Anti-Alzheimer's Therapeutic Leads
14. Pyridine-based probes and chemosensors
15. Recent advances in catalytic synthesis of pyridine derivatives
16. Pyridine as a potent antimicrobial agent and its recent discoveries
17. Synthesis of pyridine derivatives for diverse biological activity profiles: A Review


Parvesh Singh Assistant Professor, School of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa. Dr. Parvesh Singh is a seasoned synthetic organic and medicinal chemist with a keen interest in heterocyclic scaffolds and their medicinal applications. He obtained his Ph.D. in 2006 from the Guru Nanak Dev University under the supervision of Professor Mohinder P Mahajan. He is currently an Associate Professor in the School of Chemistry and Physics, University of KwaZulu Natal, Durban, South Africa where he heads a synthetic and medicinal chemistry research group. His research endeavors have produced over 100 publications in high-impact factor journals of international repute. He has successfully graduated 15 postgraduate students (7 Ph.Ds. and 8 MScs) in research since 2014. He is also a nationally recognized rated researcher by National Research Foundation (South Africa).