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Biomedical Applications of Inorganic Photochemistry

  • Book

  • November 2022
  • Elsevier Science and Technology
  • ID: 5638230

Biomedical Applications of Inorganic Photochemistry, Volume 80 in the Advances in Inorganic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include Photochemical bio-signaling with Ruthenium complexes, Adventures in the photo-uncaging of small molecule bioregulators, Challenges in medicinal inorganic chemistry and best practices to ensure rigor and reproducibility, Strategic Design of Photo-functional Transition Metal Complexes for Targeted Bioimaging and Therapy, Photoactive Manganese carbonyl Complexes with fac-{Mn(CO)3} Moiety: Design, Application, and Potential as Prodrugs in CO Therapy, Mitochondrial Targeting Metal Complexes, and more.

Other chapters cover Photoactive Organometallic Compounds with Antimicrobial Properties, Photoactivated platinum anticancer complexes, New ruthenium phthalocyanines liposomal-encapsulated in modulation of nitric oxide and singlet oxygen release: Selectivity cytotoxicity effect on cancerous cell lines, Inorganic Nanoparticles Engineered for Light-Triggered Unconventional Therapies, Mechanistic insight into phot-activation of small inorganic molecules from the biomedical application perspectives, Ruthenium Complexes for Photoactivated Dual Activity: Drug Delivery and Singlet Oxygen Generation, and Leveraging the Photophysical Properties of Rhenium(I) Tricarbonyl Complexes for Biomedical Applications.

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Table of Contents

Preface Peter C. Ford and Rudi van Eldik 1. Leveraging the photophysical properties of rhenium(I) tricarbonyl complexes for biomedical applications Justin J. Wilson 2. Strategic design of photofunctional transition metal complexes for cancer diagnosis and therapy Lawrence Cho-Cheung Lee and Kenneth Kam-Wing Lo 3. Advances in the design of photoactivated platinum anticancer complexes Huayun Shi and Peter J. Sadler 4. Adventures in the photo-uncaging of small molecule bioregulators Peter C. Ford 5. Inorganic nanoparticles engineered for light-triggered unconventional therapies Aurore Fraix and Salvatore Sortino 6. Photoactive manganese carbonyl complexes with fac-{Mn(CO)3} moiety: Design, application, and potential as prodrugs in CO therapy Indranil Chakraborty and Pradip K. Mascharak 7. Mechanistic insight into photoactivation of small inorganic molecules from the biomedical applications perspectives A. Kyziol, L. Orzel, I. Gurgul, O. Mazuryk, P. Labuz and G. Stochel 8. Ruthenium complexes for photoactivated dual activity: Drug delivery and singlet oxygen generation Sean J. Steinke, Jeremy J. Kodanko and Claudia Turro 9. Photochemical biosignaling with ruthenium complexes Oscar Filevich and Roberto Etchenique 10. Ruthenium phthalocyanines in nitric oxide modulation and singlet oxygen release: selectivity and cytotoxic effect on cancer cell lines Renata Galv?o de Lima, Rafaella Rebecchi Rios, Antonio Eduardo da Hora Machado and Roberto Santana da Silva 11. Photoactive Organometallics as Antimicrobial Agents Ashwene Rajagopal, Jack Biddulph, Leila Tabrizi, Deirdre Fitzgerald-Hughes and Mary T. Pryce 12. Mitochondria-Targeting Transition Metal Complexes Ryan J. Morris and Massimiliano Massi