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Proteomics. A Promising Approach for Cancer Research

  • Book

  • February 2023
  • Elsevier Science and Technology
  • ID: 5646511

Proteomics: A Promising Approach for Cancer Research provides an updated overview of scientific knowledge, achievements and findings in the field of cancer proteomics. The book discusses topics such as the use of proteomics in cancer biology and drug discovery, its role in surgical oncology, applications of mass spectrometry, target proteomics, single-cell proteomics, and next-generation proteomics. In addition, it discusses proteomics and phosphor-proteomics in cancer precision medicine; translation of proteomics research into clinical application; and challenges and future developments of the field. This will be a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical field who are interested in the potential of proteomics in cancer research and treatment.

The field of cancer proteomics is very dynamic, with emerging trends related to clinical solutions developed in recent years, therefore this book's content helps readers get up-to-speed on the topic to easily apply learnings into their research or clinical practice.

Please Note: This is an On Demand product, delivery may take up to 11 working days after payment has been received.

Table of Contents

1. Cancer proteomics: An overview2. Proteomics: A groundbreaking development in cancer biology3. Proteomics: Landmark advancements and challenges in cancer biomarker and drug discovery4. Proteomic profiling and its applications in cancer research5. Role of Proteomics in surgical oncology6. Applications of Mass spectrometry in understanding cancer proteomics7. Proteomics: A modern tool for identifying therapeutic targets in different type of carcinomas8. Cancer proteomics: Application of case studies in diverse cancers9. A shift from Shotgun proteomic to Targeted proteomics: A step forward in cancer research10. Applications of proteomics in cancer diagnosis11. Single-cell proteomics: Role in cancer immunotherapy12. Applications of Next-Generation Proteomics in cancer research13. Data-Independent acquisition: Application in cancer proteomics14. Applications of plasma membrane proteomics in the discovery of cancer biomarkers15. Cancer proteomic assay development: A hypothesis-driven approach16. Utility of Proteomics and phospho-proteomics in the tailored medication of cancer17. Translation of proteomic research into clinical application for cancer treatment18. Cancer proteomics: current status, challenges, and future outlook

Authors

Shafat Ali Cytogenetics and Molecular Biology Laboratory, Centre of Research for Development, University of Kashmir, Jammu and Kashmir, India. Shafat Ali (Ph.D.) pursued his BSc. from University of Kashmir and Masters in Zoology from Barkatullah Vishwavidyalaya, India. Currently he is engaged in research work for last 5 years at Cytogenetics and Molecular Biology Laboratory, Centre of Research for Development, University of Kashmir, Department of Biochemistry, Government Medical College, Srinagar, Jammu and Kashmir, and ICMR funded Multidisciplinary Research Unit, Government Medical College, Srinagar, Jammu and Kashmir, India, with specialization in the field of reproductive immunogenetics, cytokine biology, gynaecology and obstetrics, molecular biology, cancer biology and cytogenetics. He has 5 years of research experience and 5 years of teaching experience. He has more than 20 book chapters, several edited books and numerous peer-reviewed, international research publications to his credit. Mr. Ali is also the reviewer of many reputed international journals. Presently, Mr. Ali is involved in studying immunogenetic mechanisms involved in recurrent pregnancy loss Sabhiya Majid Professor and Chairperson, Department of Biochemistry, Government Medical College, Srinagar, India. Sabhiya Majid, Ph.D. is a Professor and Chairperson of the Department of Biochemistry, Govt. Medical College Srinagar (GMC Sgr.), J&K, India. Prof. Majid has 30 years of experience in teaching, research and diagnostic biochemistry, having published around 100 research papers in journals of repute, many books and 12 book chapters. She has been the recipient of several fellowships, awards and grants from various reputed funding agencies. She has been the nodal officer and implemented various research and infrastructure development schemes including Fund for Improvement of Science & Technology Infrastructure, Department of Science & Technology, Govt. of India. She is a member of several scientific associations and boards of undergraduate, postgraduate and research studies. She is on the reviewer panel of a number of online peer-reviewed journals. Having moved on from her doctoral work on nutritional modulation of carcinogenesis to understanding the molecular basis of various disease processes, her current research focuses on non invasive cancer markers. Muneeb U Rehman College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Muneeb U Rehman (Ph.D.) is a Faculty member at College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. He holds a doctorate in Toxicology (specialization in cancer biology and natural product research) from Jamia Hamdard, New Delhi, India. Dr. Rehman has more than 10 years of research and teaching experience in the field of toxicology, cancer biology, natural product pharmacology and pharmacogenomics. He is the recipient of several national and international fellowships and awards. He has published more than 100 research papers in peer-reviewed, international journals, and has 5 edited books and 30 book chapters. Dr. Rehman is on the editorial boards and is a reviewer of several high-impact, international scientific journals. He is also a life member of various international societies and organizations. Currently, Dr. Rehman is engaged in studying the molecular mechanisms of cancer prevention by natural products and the role of pharmacogenomics and toxicogenomics in evaluating the effectiveness and safety of drugs.