+353-1-416-8900REST OF WORLD
+44-20-3973-8888REST OF WORLD
1-917-300-0470EAST COAST U.S
1-800-526-8630U.S. (TOLL FREE)

Global Orthopedic Biomaterials Market Size, Share and COVID-19 Impact Analysis 2023-2029 MedSuite Includes: Bone Graft Substitutes, Orthopedic Growth Factors, and 3 more

  • PDF Icon


  • 421 Pages
  • December 2022
  • Region: Global
  • iData Research
  • ID: 5715396
In 2022, the global orthopedic biomaterials device market was valued at $5.6 billion. This is anticipated to increase over the forecast period at a CAGR of 3.4% to reach $7.1 billion.

The full report suite on the global market for orthopedic biomaterials includes bone graft substitutes, growth factors, cell therapy, hyaluronic acid viscosupplementation and cartilage repair (appendix only).


  • Unit Sales, Average Selling Prices, Market Value & Growth Trends
  • Forecasts Until 2028, and Historical Data to 2018
  • Market Drivers & Limiters for Each Segment
  • Competitive Analysis with Market Shares for Each Segment
  • Recent Mergers & Acquisitions
  • Procedure Volumes
  • Company Profiles, Product Portfolios and SWOT for Top Competitors
  • COVID-19 Impact Analysis


By the year 2030, elder persons are anticipated to outnumber children under the age of 10 (1.41 billion versus 1.35 billion), and, by 2050, projections indicate that there will be a greater number of persons aged 60 or over than adolescents aged 10-24 (2.1 billion versus 2.0 billion). The aging of the population will significantly impact the orthopedic biomaterials device market, increasing the prevalence of bone diseases and the need for treating them. However, orthopedic biomaterials device markets were negatively impacted by COVID-19 in the short term due to mass cancellations and postponements of procedures across all countries.


Overall, within the Global orthopedic biomaterials market there are three leading competitors: Medtronic, DePuy Synthes, and Stryker. Medtronic has maintained a strong presence in the total orthopedic Biomaterials device market through a variety of characteristics including brand recognition, strong customer support and a large sales force. The company held the largest share of the orthopedic bone graft substitute segment and dominated in the orthopedic growth factor market because of the success of its INFUSE™ product.


You can view all these included reports and segmentation here:

Orthopedic Bone Graft Substitutes Market - MedCore - Includes:
  • Allograft BGS, demineralized bone matrix allograft BGS and synthetic BGS.
  • Orthopedic Growth Factor Market - MedCore
  • Orthopedic Cell Therapy Market - MedCore - Includes:
  • Platelet-rich plasma and bone marrow therapy segments.
  • Hyaluronic Acid Viscosupplementation Market - MedCore - Includes:
  • Single-injection, Two-injection, Three-Injection, and Five-Injection products.
*In Appendix* Orthopedic Cartilage Repair Market - MedCore - Includes:
  • Osteochondral allografts, meniscal allografts, and autologous chondrocytes.


Regions : North America (Canada, United States), Latin America (Argentina, Brazil, Chile, Colombia, Mexico, Peru, Venezuela), Western Europe (Austria, Benelux, France, Germany, Italy, Portugal, Scandinavia, Spain, Switzerland, U.K.), Central & Eastern Europe (Baltic States, Bulgaria, Croatia, Czech Republic, Greece, Hungary, Kazakhstan, Poland, Romania, Russia, Turkey, Ukraine), Middle East (Bahrain, Iran, Israel, Kuwait, Oman, Qatar, Saudi Arabia, United Arab Emirates), Asia Pacific (Australia, Cambodia, China, Hong Kong, India, Indonesia, Japan, Malaysia, Myanmar, New Zealand, Philippines, Singapore, South Korea, Taiwan, Thailand, Vietnam), Africa (Algeria, Egypt, Ghana, Kenya, Libya, Morocco, Nigeria, South Africa, Sudan, Uganda)

Base Year: 2022

Forecast: 2023-2029

Historical Data: 2019-2022

Quantitative Coverage: Market Size, Market Shares, Market Forecasts, Market Growth Rates, Units Sold, and Average Selling Prices.

Qualitative Coverage: COVID19 Impact, Market Growth Trends, Market Limiters, Competitive Analysis & SWOT for Top Competitors, Mergers & Acquisitions, Company Profiles, Product Portfolios, FDA Recalls, Disruptive Technologies, Disease Overviews.

Data Sources: Primary Interviews with Industry Leaders, Government Physician Data, Regulatory Data, Hospital Private Data, Import & Export Data, Internal Database.

Table of Contents

1. Executive summary
Global Orthopedic Biomaterials Device Market Overview
Competitive Analysis
Market Trends
Market Developments
Procedures Included
Markets Included
Regions Included
Version History
Research methodology
Step 1: Project Initiation & Team Selection
Step 2: Prepare Data Systems and Perform Secondary Research
Step 3: Preparation for Interviews & Questionnaire Design
Step 4: Performing Primary Research
Step 5: Research Analysis: Establishing Baseline Estimates
Step 6: Market Forecast and Analysis
Step 7: Identify Strategic Opportunities
Step 8: Final Review and Market Release
Step 9: Customer Feedback and Market Monitoring

2. Impact of covid-19 on THE global Orthopedic Biomaterials DEVICE Market
2.1 Introduction
2.2 Regional Profiles
2.3 Analysis By Market Segment
2.3.1 Worst Case Scenario
2.3.2 Base Case Scenario
2.3.3 Best Case Scenario

3. Product Assessment
3.1 Introduction
3.2 Product Portfolios
3.2.1 Bone Graft Substitute
3.2.2 Growth Factors NELL-1 Bone Biologics INFUSE® by Medtronic OsteoAMP® by Bioventus Surgical OP-1™ by Stryker/Olympus Biotech (Delisted) The Osteogrow Study AUGMENT® Bone Graft Amplex® Osteobiologic Bone Graft Substitute i-Factor™ Peptide Bone Matrix
3.2.3 Cell Therapy Platelet-Rich Plasma Bone Marrow Aspirate Concentrate
3.2.4 Hyaluronic Acid Viscosupplementation (HAV)
3.2.5 Cartilage Repair
3.3 Regulatory Issues and Recalls
3.3.1 Bioventus Bone Graft Substitute
3.3.2 Cerapedics Growth Factor
3.3.3 Exactech Bone Graft Substitute
3.3.4 Medtronic Bone Graft Substitute
3.3.5 Sanofi Hyaluronic Acid Viscosupplementation
3.3.6 Wright Medical (Stryker) Bone Graft Substitute
3.3.7 Xtant Bone Graft Substitute
3.3.8 Zimmer Biomet Growth Factor
3.4 Clinical Trials
3.4.1 Aesculap Cartilage Repair
3.4.2 Arthrex Bone Graft Substitute
3.4.3 Cerapedics Bone Graft Substitute
3.4.4 Medtronic Growth Factor
3.4.5 Surgalign Holdings Bone Graft Substitute
3.4.6 Stryker Bone Graft Substitute
3.4.7 Tetec Cartilage Repair
3.4.8 Vericel Cartilage Repair
3.4.9 Others Bone Graft Substitute Growth Factor Cell Therapy Hyaluronic Acid Viscosupplementation Cartilage Repair

4. Global Orthopedic Biomaterials Device Market Overview
4.1 Introduction
4.2 Market Overview & Trend Analysis
4.2.1 By Segment
4.2.2 By Region
4.3 Drivers and Limiters
4.3.1 Market Drivers
4.3.2 Market Limiters
4.4 Competitive Market Share Analysis
4.5 Mergers and Acquisitions
4.6 Company Profiles
4.6.1 Arthrex
4.6.2 Bioventus
4.6.3 DePuy Synthes
4.6.4 Ferring Pharmaceuticals
4.6.5 Fidia Farmaceutici
4.6.6 Harvest Technologies (Terumo BCT)
4.6.7 Medtronic
4.6.8 Musculoskeletal Transplant Foundation (MTF)
4.6.9 Surgalign Holdings (former RTI Surgical)
4.6.10 Sanofi
4.6.11 SeaSpine
4.6.12 Stryker
4.6.13 Vericel
4.6.14 Zimmer Biomet
4.7 SWOT Analysis
4.7.1 Arthrex
4.7.2 Bioventus
4.7.3 DePuy Synthes
4.7.4 Ferring Pharmaceuticals
4.7.5 Fidia Farmaceutici
4.7.6 Harvest Technologies (Terumo BCT)
4.7.7 Medtronic
4.7.8 Musculoskeletal Transplant Foundation (MTF)
4.7.9 Surgalign Holdings (former RTI Surgical)
4.7.10 Sanofi
4.7.11 SeaSpine
4.7.12 Stryker
4.7.13 Vericel
4.7.14 Zimmer Biomet

5. Orthopedic Bone Graft Substitute Market
5.1 Executive Summary
5.1.1 Global Orthopedic Bone Graft Substitute Market Overview
5.1.2 Competitive Analysis
5.1.3 Regions Included
5.2 Introduction
5.3 Procedure Numbers
5.3.1 Total Orthopedic Bone Grafting Procedures
5.3.2 Allograft Procedures
5.3.3 Demineralized Bone Matrix Procedures
5.3.4 Synthetic Procedures
5.4 Market Overview
5.4.1 By Segment
5.4.2 By Region
5.5 Market Analysis and Forecast
5.5.1 Total Orthopedic Bone Graft Substitute Market
5.5.2 Allograft Bone Graft Substitute Market
5.5.3 Demineralized Bone Matrix Allograft Bone Graft Substitute Market
5.5.4 Synthetic Bone Graft Substitute Market
5.6 Unit Analysis
5.6.1 Allograft Bone Graft Substitute Unit Analysis Allograft Bone Graft Substitute Units Sold by Indication
5.6.2 Demineralized Bone Matrix Allograft Bone Graft Substitute Unit Analysis Demineralized Bone Matrix Allograft Bone Graft Substitute Units Sold by Indication
5.6.3 Synthetic Bone Graft Substitute Unit Analysis Synthetic Bone Graft Substitute Units Sold by Indication
5.7 Drivers and Limiters
5.7.1 Market Drivers
5.7.2 Market Limiters
5.8 Competitive Market Share Analysis

6. Orthopedic Growth Factor Market
6.1 Executive Summary
6.1.1 Global Orthopedic Growth Factor Market Overview
6.1.2 Competitive Analysis
6.1.3 Regions Included
6.2 Introduction
6.3 Procedure Numbers
6.4 Market Analysis and Forecast
6.5 Drivers and Limiters
6.5.1 Market Drivers
6.5.2 Market Limiters
6.6 Competitive Market Share Analysis

7. Orthopedic Cell Therapy Market
7.1 Executive Summary
7.1.1 Global Orthopedic Cell Therapy Market Overview
7.1.2 Competitive Analysis
7.1.3 Regions Included
7.2 Introduction
7.2.1 Platelet-Rich Plasma
7.2.2 Concentrated Bone Marrow Aspirate
7.3 Procedure Numbers
7.3.1 Total Orthopedic Cell Therapy Procedures
7.3.2 Platelet-Rich Plasma Procedures
7.3.3 Bone Marrow Aspirate Concentrate Procedures
7.4 Market Overview
7.4.1 By Segment
7.4.2 By Region
7.5 Market Analysis and Forecast
7.5.1 Platelet-Rich Plasma Market
7.5.2 Bone Marrow Aspirate Concentrate Market
7.6 Drivers and Limiters
7.6.1 Market Drivers
7.6.2 Market Limiters
7.7 Competitive Market Share Analysis

8. Hyaluronic Acid Viscosupplementation Market
8.1 Executive Summary
8.1.1 Global Hyaluronic Acid Viscosupplementation Market Overview
8.1.2 Competitive Analysis
8.1.3 Regions Included
8.2 Introduction
8.2.1 Benefits of Viscosupplementation
8.2.2 Synovial Fluid
8.2.3 Product Types Single-Injection Products Two-Injection Cycle Products Three-Injection Cycle Products Three-/Five-Injection Cycle Products
8.3 Procedure Numbers
8.4 Market Overview
8.4.1 By Segment
8.4.2 By Region
8.5 Market Analysis and Forecast
8.5.1 Total Hyaluronic Acid Viscosupplementation Market
8.5.2 Single-Injection Hyaluronic Acid Viscosupplementation Market
8.5.3 Two-Injection Hyaluronic Acid Viscosupplementation Market
8.5.4 Three-Injection Hyaluronic Acid Viscosupplementation Market
8.5.5 Five-Injection Hyaluronic Acid Viscosupplementation Market
8.6 Drivers and Limiters
8.6.1 Market Drivers
8.6.2 Market Limiters
8.7 Competitive Market Share Analysis

9. Appendix: Orthopedic Cartilage Repair Market
9.1 Executive Summary
9.1.1 Global Orthopedic Cartilage Repair Market Overview
9.1.2 Regions Included
9.2 Introduction
9.2.1 Anatomy
9.2.2 Methods for Cartilage Repair Microfracture Microfracture Adjunct Osteoarticular Autograft Transfer System Particulated Juvenile Allograft Osteochondral Allograft Transfer Autologous Chondrocyte Implantation Meniscal Allograft Transplantation
9.3 Procedure Numbers
9.3.1 Total Orthopedic Cartilage Repair Procedures
9.3.2 Osteochondral Allograft Procedures
9.3.3 Meniscal Allograft Procedures
9.3.4 Autologous Chondrocyte Implantation Procedures
9.4 Market Overview
9.4.1 By Segment
9.4.2 By Region
9.5 Market Analysis and Forecast
9.5.1 Total Orthopedic Cartilage Repair Market
9.5.2 Osteochondral Allograft Market
9.5.3 Meniscal Allograft Market
9.5.4 Autologous Chondrocyte Implantation Market
9.6 Drivers and Limiters
9.6.1 Market Drivers
9.6.2 Market Limiters
9.7 Competitive Market Share Analysis

10. Abbreviations

Companies Mentioned

A selection of companies mentioned in this report includes:

  • Adistem
  • Harvest Terumo
  • AlloSource
  • IBSA Pharma
  • Alphatec
  • Integra LifeSciences
  • Anika Therapeutics
  • Isto Biologics
  • Arthrex
  • Kuros
  • Aziyo
  • LifeLink Tissue Bank
  • Baxter
  • LifeNet Health
  • Berkley Advanced Biomaterials
  • Medtronic
  • BioCell
  • MTF
  • Biocomposites
  • Novabone
  • Bioiberica
  • Nuo Therapeutics
  • Biologica
  • NuVasive
  • Bioventus
  • Orthofix
  • Celling Biosciences
  • OrthogenRx
  • Cerapedics
  • Osteogenics
  • CO.DON
  • Osteomed
  • Collagen Matrix
  • Ostetic
  • Community Tissue Services
  • Prospec
  • RTI Surgical
  • Croma-Pharma
  • Sanofi
  • Curasan
  • SeaSpine
  • DCI Donor Services
  • Smith & Nephew
  • DePuy Synthes
  • Spinal Elements
  • Documedica
  • Stryker
  • Ember Therapeutics
  • Surgalign Holdings
  • Etex
  • Exactech
  • ThermoGenesis
  • Ferring Pharmaceuticals
  • Vericel
  • Fidia
  • Vivex
  • Geistlich
  • Xtant
  • Globus Medical
  • Zimmer Biomet