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Opioid Induced Constipation Market - Global Forecast 2025-2032

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    Report

  • 186 Pages
  • November 2025
  • Region: Global
  • 360iResearch™
  • ID: 5715749
UP TO OFF until Jan 01st 2026
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Senior executives in the healthcare sector are facing increasing operational and regulatory complexity in the opioid induced constipation market. Rapid changes in clinical requirements and compliance frameworks make continuous market intelligence and agile planning critical for sustained business resilience and growth.

Market Snapshot: Growth and Dynamics in the Opioid Induced Constipation Market

The opioid induced constipation market is demonstrating steady expansion, propelled by the ongoing demand for effective constipation therapies linked to widespread opioid prescriptions in patient care. From 2024 to 2032, industry forecasts project growth from USD 70.10 million to USD 119.94 million, representing a compound annual growth rate (CAGR) of 6.94%.

Major contributors to this momentum include a higher prevalence of pain management protocols, heightened attention to tailored patient solutions, and increased R&D focus on innovative pharmaceuticals. Organizations are also adapting product strategies and operational practices to meet the requirements of diverse regulatory landscapes and to maintain competitive positioning.

Scope & Segmentation

This report equips senior leaders with actionable market intelligence across all critical areas:

  • Product Type: Analysis covers combination treatments, osmotic and stimulant laxatives, stool softeners, and peripherally acting mu-opioid receptor antagonists, including alvimopan, methylnaltrexone, naldemedine, and naloxegol.
  • Administration Route: Evaluates oral and rectal therapy options, such as suspensions, capsules, tablets, enemas, and suppositories, relevant to varied patient care settings and acute or chronic treatment needs.
  • Regional Coverage: Includes trends and market dynamics across the Americas, Europe, Middle East, Africa, and Asia-Pacific, emphasizing established markets like the United States, Canada, Japan, and Australia, as well as growth regions such as Southeast Asia, China, and India.
  • Key Companies: Reviews strategies and portfolios of AstraZeneca plc, Shionogi & Co., Ltd., H. Lundbeck A/S, Bausch Health Companies Inc., Mundipharma International Limited, Merck & Co., Inc., and Valinor Pharma, LLC.

Segment insights highlight geographic variations, technology adoption patterns, and strategic pathways for process optimization and targeted expansion.

Key Takeaways

  • Peripherally acting opioid antagonists are preferred in clinical environments requiring ongoing pain management while minimizing opioid-related side effects for patient well-being.
  • Broad availability of both oral and rectal treatments improves the ability of healthcare teams to address patients' varying needs, supporting long-term and outpatient care delivery.
  • Adoption of digital tools and telemedicine solutions supports real-time monitoring, optimizes therapy management, and elevates workflow efficiency without interrupting care delivery.
  • Strategically diversified supply chains and adaptable sourcing arrangements help buffer cost fluctuations and ensure stable product access throughout shifting distribution conditions.
  • Regional adaptation of reimbursement and regulatory approaches supports product launches and compliance, directly influencing successful entry into new markets.
  • Collaboration with advocacy groups and technology partners enhances reach, generates robust real-world data, and informs market strategies closely aligned with evolving patient preferences.

Tariff Impact on Accessibility and Pricing

Anticipated U.S. tariffs beginning in 2025 are prompting market participants to reassess sourcing approaches and pricing strategies. Senior management teams are enhancing local and regional supply infrastructure and exploring innovative contracting models, such as value-based and risk-sharing agreements, to uphold patient access and operational robustness. These tactics are designed to sustain business continuity in changing policy and industry contexts.

Methodology & Data Sources

The report relies on a comprehensive, integrated research process combining peer-reviewed studies, regulatory documentation, and clinical trial data. Validation includes insights from interviews with clinicians, payers, and advocacy leaders across multiple regional markets, ensuring findings reflect current treatment patterns and emerging technologies.

Why This Report Matters

  • Executives gain practical benchmarks and market analytics that align operational strategies with ongoing regulatory and healthcare environment shifts.
  • Segment-by-segment analysis and relevant technology trends support informed investment, resource planning, and opportunity identification.
  • Intelligence reduces risk from supply chain disruptions and enables effective product launches in pivotal regional and clinical segments.

Conclusion

This report enables organizations to proactively address industry change, strengthen operational agility, and achieve patient-focused outcomes in an evolving therapeutic setting. Applied insights empower confident strategic planning and responsive execution.

 

Additional Product Information:

  • Purchase of this report includes 1 year online access with quarterly updates.
  • This report can be updated on request. Please contact our Customer Experience team using the Ask a Question widget on our website.

Table of Contents

1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders
2. Research Methodology
3. Executive Summary
4. Market Overview
5. Market Insights
5.1. Rising uptake of peripherally acting mu-opioid receptor antagonists in hospitalized patients with chronic cancer pain management
5.2. Expansion of novel oral small molecule treatments targeting opioid-induced constipation symptoms in outpatient settings
5.3. Integration of digital therapeutics and mobile health apps for real-time monitoring of opioid-induced constipation severity
5.4. Increasing investment in extended-release combination opioid formulations with built-in constipation mitigation mechanisms
5.5. Impact of recent FDA label expansions for naloxegol and naldemedine on opioid-induced constipation treatment algorithms
5.6. Market penetration of linaclotide and plecanatide beyond irritable bowel syndrome for opioid-induced constipation off-label use
5.7. Adoption of patient-centric reimbursement models to improve access to expensive opioid-induced constipation therapies
5.8. Influence of clinical guidelines advocating early intervention for opioid-induced constipation among palliative care populations
5.9. Role of telemedicine consultations in optimizing management strategies for opioid-induced constipation in rural healthcare settings
5.10. Emergence of over-the-counter opioid-induced constipation remedies and their effect on prescription market dynamics
6. Cumulative Impact of United States Tariffs 2025
7. Cumulative Impact of Artificial Intelligence 2025
8. Opioid Induced Constipation Market, by Product Type
8.1. Combination Therapies
8.2. Laxatives
8.2.1. Osmotic Laxatives
8.2.2. Stimulant Laxatives
8.2.3. Stool Softeners
8.3. Peripherally Acting Mu-Opioid Receptor Antagonists
8.3.1. Alvimopan
8.3.2. Methylnaltrexone
8.3.3. Naldemedine
8.3.4. Naloxegol
9. Opioid Induced Constipation Market, by Oral
9.1. Liquid
9.1.1. Solutions
9.1.2. Suspensions
9.2. Solid
9.2.1. Capsules
9.2.2. Tablets
10. Opioid Induced Constipation Market, by Rectal
10.1. Enemas
10.2. Suppositories
11. Opioid Induced Constipation Market, by Region
11.1. Americas
11.1.1. North America
11.1.2. Latin America
11.2. Europe, Middle East & Africa
11.2.1. Europe
11.2.2. Middle East
11.2.3. Africa
11.3. Asia-Pacific
12. Opioid Induced Constipation Market, by Group
12.1. ASEAN
12.2. GCC
12.3. European Union
12.4. BRICS
12.5. G7
12.6. NATO
13. Opioid Induced Constipation Market, by Country
13.1. United States
13.2. Canada
13.3. Mexico
13.4. Brazil
13.5. United Kingdom
13.6. Germany
13.7. France
13.8. Russia
13.9. Italy
13.10. Spain
13.11. China
13.12. India
13.13. Japan
13.14. Australia
13.15. South Korea
14. Competitive Landscape
14.1. Market Share Analysis, 2024
14.2. FPNV Positioning Matrix, 2024
14.3. Competitive Analysis
14.3.1. AstraZeneca plc
14.3.2. Shionogi & Co., Ltd.
14.3.3. H. Lundbeck A/S
14.3.4. Bausch Health Companies Inc.
14.3.5. Mundipharma International Limited
14.3.6. Merck & Co., Inc.
14.3.7. Valinor Pharma, LLC

Companies Mentioned

The companies profiled in this Opioid Induced Constipation market report include:
  • AstraZeneca PLC
  • Shionogi & Co., Ltd.
  • H. Lundbeck A/S
  • Bausch Health Companies Inc.
  • Mundipharma International Limited
  • Merck & Co., Inc.
  • Valinor Pharma, LLC

Table Information