The global mRNA vaccines and therapeutics market size reached US$ 56.1 Billion in 2022. Looking forward, the publisher expects the market to reach US$ 66.2 Billion by 2028, exhibiting a CAGR of 2.8% during 2022-2028.
Messenger Ribonucleic Acid (mRNA) refers to a single protein-coding gene in the genome that acts as a basis for protein synthesis within the cells. mRNA vaccines and therapeutics combine the desirable immunological properties and are prepared in laboratories using mammalian cells. Some of the common types of vaccines and therapeutics include self-amplifying, non-replicating, in vivo self-replicating and in vitro dendritic cell non-replicating mRNA. They are injected into the body to trigger virus-detecting immune sensors and produce viral antigen proteins within the cells. This aids in enhancing the body's immunity by improving B- and T-cell responses.
The rising prevalence of medical ailments, such as diabetes, tuberculosis, cancer and cardiovascular diseases (CVDs), is one of the key factors driving the growth of the market. The increasing demand for therapeutic medicines and vaccines for Ebola, influenza, Human Immunodeficiency Virus (HIV) and other viral infections is also providing a boost to the market growth. In comparison to conventional medicines, mRNA vaccines and therapeutics are developed using advanced technologies that are more effective against pathogens, have higher potency, enhanced immunogenicity and are relatively more cost-effective. Additionally, improvements in the lipid nanoparticle formulations for in-vivo systemic delivery of mRNA are also creating a positive outlook for the market. Pharmaceutical companies are investing in mRNA technologies as they can combine multiple molecules into a therapeutic medicine, which is acting as another major growth-inducing factor. Other factors, including extensive research and development (R&D) activities in the field of biotechnology, along with improvements in the healthcare technologies, are projected to drive the market further.
2. What is the expected growth rate of the global mRNA vaccines and therapeutics market during 2023-2028?
3. What are the key factors driving the global mRNA vaccines and therapeutics market?
4. What has been the impact of COVID-19 on the global mRNA vaccines and therapeutics market?
5. What is the breakup of the global mRNA vaccines and therapeutics market based on the vaccine type?
6. What is the breakup of the global mRNA vaccines and therapeutics market based on the treatment type?
7. What is the breakup of the global mRNA vaccines and therapeutics market based on vaccine manufacturing?
8. What is the breakup of the global mRNA vaccines and therapeutics market based on the application?
9. What is the breakup of the global mRNA vaccines and therapeutics market based on the end-user?
10. What are the key regions in the global mRNA vaccines and therapeutics market?
11. Who are the key players/companies in the global mRNA vaccines and therapeutics market?
Messenger Ribonucleic Acid (mRNA) refers to a single protein-coding gene in the genome that acts as a basis for protein synthesis within the cells. mRNA vaccines and therapeutics combine the desirable immunological properties and are prepared in laboratories using mammalian cells. Some of the common types of vaccines and therapeutics include self-amplifying, non-replicating, in vivo self-replicating and in vitro dendritic cell non-replicating mRNA. They are injected into the body to trigger virus-detecting immune sensors and produce viral antigen proteins within the cells. This aids in enhancing the body's immunity by improving B- and T-cell responses.
The rising prevalence of medical ailments, such as diabetes, tuberculosis, cancer and cardiovascular diseases (CVDs), is one of the key factors driving the growth of the market. The increasing demand for therapeutic medicines and vaccines for Ebola, influenza, Human Immunodeficiency Virus (HIV) and other viral infections is also providing a boost to the market growth. In comparison to conventional medicines, mRNA vaccines and therapeutics are developed using advanced technologies that are more effective against pathogens, have higher potency, enhanced immunogenicity and are relatively more cost-effective. Additionally, improvements in the lipid nanoparticle formulations for in-vivo systemic delivery of mRNA are also creating a positive outlook for the market. Pharmaceutical companies are investing in mRNA technologies as they can combine multiple molecules into a therapeutic medicine, which is acting as another major growth-inducing factor. Other factors, including extensive research and development (R&D) activities in the field of biotechnology, along with improvements in the healthcare technologies, are projected to drive the market further.
Key Market Segmentation:
The publisher provides an analysis of the key trends in each sub-segment of the global mRNA vaccines and therapeutics market report, along with forecasts at the global, regional and country level from 2023-2028. Our report has categorized the market based on vaccine type, treatment type, vaccine manufacturing, application and end-user.Breakup by Vaccine Type:
- Self-amplifying mRNA-Based Vaccines
- Conventional Non-Amplifying mRNA-Based Vaccines
Breakup by Treatment Type:
- Bioengineered Vaccine
- Gene Therapy
- Gene Transcription
- Cell Therapy
- Monoclonal Antibody
- Others
Breakup by Vaccine Manufacturing:
- In-House
- Out-Sourced
Breakup by Application:
- Cancer
- Infectious Disease
- Gene Editing
- Protein Replacement
Breakup by End-User:
- Hospitals and Clinics
- Research Organizations
- Others
Breakup by Region:
- North America
- United States
- Canada
- Asia Pacific
- China
- Japan
- India
- South Korea
- Australia
- Indonesia
- Others
- Europe
- Germany
- France
- United Kingdom
- Italy
- Spain
- Russia
- Others
- Latin America
- Brazil
- Mexico
- Others
- Middle East and Africa
Competitive Landscape:
The competitive landscape of the industry has also been examined with some of the key players being Arcturus Therapeutics Inc., BioNTech SE, CureVac AG, eTheRNA immunotherapies NV, ethris GmbH, GlaxoSmithKline PLC, Moderna Therapeutics Inc., Translate Bio Inc., Argos Therapeutics, Inc., Sangamo Therapeutics Inc. and Pfizer Inc, etc.Key Questions Answered in This Report
1. What was the size of the global mRNA vaccines and therapeutics market in 2022?2. What is the expected growth rate of the global mRNA vaccines and therapeutics market during 2023-2028?
3. What are the key factors driving the global mRNA vaccines and therapeutics market?
4. What has been the impact of COVID-19 on the global mRNA vaccines and therapeutics market?
5. What is the breakup of the global mRNA vaccines and therapeutics market based on the vaccine type?
6. What is the breakup of the global mRNA vaccines and therapeutics market based on the treatment type?
7. What is the breakup of the global mRNA vaccines and therapeutics market based on vaccine manufacturing?
8. What is the breakup of the global mRNA vaccines and therapeutics market based on the application?
9. What is the breakup of the global mRNA vaccines and therapeutics market based on the end-user?
10. What are the key regions in the global mRNA vaccines and therapeutics market?
11. Who are the key players/companies in the global mRNA vaccines and therapeutics market?
Table of Contents
1 Preface2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 Executive Summary
4 Introduction
4.1 Overview
4.2 Key Industry Trends
5 Introduction to mRNA Vaccines and Therapeutics
5.1 History of mRNA Vaccines and Therapeutics Development
5.2 Incidence and Prevalence of Chronic Diseases and Major Infectious Diseases
5.3 Prevention and Treatment Using mRNA Vaccines and Therapeutics
5.3.1 mRNA Modifications
5.3.2 mRNA Efficiencies
5.3.3 Adjuvant/Stimulant and Carrier Technologies for mRNA-Based Vaccines
5.3.4 Carriers for mRNA-Based Protein and Antibody Therapeutics
6 Global mRNA Vaccines and Therapeutics Market
6.1 Market Potential Overview
6.2 Market Potential
6.3 Impact of COVID-19
6.4 mRNA Vaccines in Pipeline
7 Market Breakup by Vaccine Type
7.1 Self-amplifying mRNA-Based Vaccines
7.2 Conventional Non-Amplifying mRNA-Based Vaccines
8 Market Breakup by Treatment Type
8.1 Gene Therapy
8.2 Monoclonal Antibody
8.3 Gene Transcription
8.4 Cell Therapy
8.5 Bioengineered Vaccine
8.6 Others
9 Market Breakup by Vaccine Manufacturing
9.1 In-House
9.2 Out-Sourced
10 Market Breakup by Application
10.1 Cancer
10.2 Infectious Disease
10.3 Gene Editing
10.4 Protein Replacement
11 Market Breakup by End-User
11.1 Hospitals and Clinics
11.2 Research Organizations
11.3 Others
12 Market Breakup by Region
12.1 North America
12.1.1 Market Breakup by Country
12.1.1.1 United States
12.1.1.2 Canada
12.2 Europe
12.2.1 Market Breakup by Country
12.2.1.1 Germany
12.2.1.2 United Kingdom
12.2.1.3 France
12.2.1.4 Italy
12.2.1.5 Spain
12.2.1.6 Russia
12.2.1.7 Others
12.3 Asia Pacific
12.3.1 Market Breakup by Country
12.3.1.1 Japan
12.3.1.2 China
12.3.1.3 Australia
12.3.1.4 South Korea
12.3.1.5 India
12.3.1.6 Indonesia
12.3.1.7 Others
12.4 Latin America
12.4.1 Market Breakup by Country
12.4.1.1 Brazil
12.4.1.2 Mexico
12.4.1.3 Others
12.5 Middle East and Africa
12.5.1 Market Breakup by Country
13 SWOT Analysis
13.1 Overview
13.2 Strengths
13.3 Weaknesses
13.4 Opportunities
13.5 Threats
14 Value Chain Analysis
15 Porters Five Forces Analysis
15.1 Overview
15.2 Bargaining Power of Buyers
15.3 Bargaining Power of Suppliers
15.4 Degree of Competition
15.5 Threat of New Entrants
15.6 Threat of Substitutes
16 Competitive Landscape
16.1 Market Structure
16.2 Key Players
16.3 Profiles of Key Players
16.3.1 Arcturus Therapeutics, Inc.
16.3.2 BioNTech SE
16.3.3 CureVac AG
16.3.4 eTheRNA immunotherapies NV
16.3.5 ethris GmbH
16.3.6 GlaxoSmithKline PLC
16.3.7 Moderna Therapeutics Inc.
16.3.8 Translate Bio Inc.
16.3.9 Argos Therapeutics, Inc.
16.3.10 Sangamo Therapeutics Inc.
16.3.11 Pfizer Inc.
List of Figures
Figure 1: Global: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Billion US$), 2023-2028
Figure 2: Global: mRNA Vaccines and Therapeutics Market Potential (Self-amplifying mRNA-Based Vaccines): Value Trends (in Billion US$), 2023-2028
Figure 3: Global: mRNA Vaccines and Therapeutics Market Potential (Conventional Non-Amplifying mRNA-Based Vaccines): Value Trends (in Billion US$), 2023-2028
Figure 4: Global: mRNA Vaccines and Therapeutics Market Potential (Gene Therapy): Value Trends (in Billion US$), 2023-2028
Figure 5: Global: mRNA Vaccines and Therapeutics Market Potential (Monoclonal Antibody): Value Trends (in Billion US$), 2023-2028
Figure 6: Global: mRNA Vaccines and Therapeutics Market Potential (Gene Transcription): Value Trends (in Billion US$), 2023-2028
Figure 7: Global: mRNA Vaccines and Therapeutics Market Potential (Cell Therapy): Value Trends (in Billion US$), 2023-2028
Figure 8: Global: mRNA Vaccines and Therapeutics Market Potential (Bioengineered Vaccine): Value Trends (in Billion US$), 2023-2028
Figure 9: Global: mRNA Vaccines and Therapeutics Market Potential (Other Treatment Types): Value Trends (in Billion US$), 2023-2028
Figure 10: Global: mRNA Vaccines and Therapeutics Market Potential (In-House): Value Trends (in Billion US$), 2023-2028
Figure 11: Global: mRNA Vaccines and Therapeutics Market Potential (Out-Sourced): Value Trends (in Billion US$), 2023-2028
Figure 12: Global: mRNA Vaccines and Therapeutics Market Potential (Cancer): Value Trends (in Billion US$), 2023-2028
Figure 13: Global: mRNA Vaccines and Therapeutics Market Potential (Infectious Disease): Value Trends (in Billion US$), 2023-2028
Figure 14: Global: mRNA Vaccines and Therapeutics Market Potential (Gene Editing): Value Trends (in Billion US$), 2023-2028
Figure 15: Global: mRNA Vaccines and Therapeutics Market Potential (Protein Replacement): Value Trends (in Billion US$), 2023-2028
Figure 16: Global: mRNA Vaccines and Therapeutics Market Potential (Hospitals and Clinics): Value Trends (in Billion US$), 2023-2028
Figure 17: Global: mRNA Vaccines and Therapeutics Market Potential (Research Organizations): Value Trends (in Billion US$), 2023-2028
Figure 18: Global: mRNA Vaccines and Therapeutics Market Potential (Other End-Users): Value Trends (in Billion US$), 2023-2028
Figure 19: North America: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Billion US$), 2023-2028
Figure 20: North America: mRNA Vaccines and Therapeutics Market Potential: Breakup by Country (in %), 2022
Figure 21: United States: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 22: Canada: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 23: Europe: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Billion US$), 2023-2028
Figure 24: Europe: mRNA Vaccines and Therapeutics Market Potential: Breakup by Country (in %), 2022
Figure 25: Germany: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 26: United Kingdom: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 27: France: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 28: Italy: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 29: Spain: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 30: Russia: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 31: Others: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 32: Asia Pacific: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Billion US$), 2023-2028
Figure 33: Asia Pacific: mRNA Vaccines and Therapeutics Market Potential: Breakup by Country (in %), 2022
Figure 34: Japan: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 35: China: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 36: Australia: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 37: South Korea: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 38: India: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 39: Indonesia: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 40: Others: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 41: Latin America: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Billion US$), 2023-2028
Figure 42: Latin America: mRNA Vaccines and Therapeutics Market Potential: Breakup by Country (in %), 2022
Figure 43: Brazil: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 44: Mexico: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 45: Others: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Million US$), 2023-2028
Figure 46: Middle East and Africa: mRNA Vaccines and Therapeutics Market Potential: Value Trends (in Billion US$), 2023-2028
Figure 47: Middle East and Africa: mRNA Vaccines and Therapeutics Market Potential: Breakup by Country (in %), 2022
Figure 48: Global: mRNA Vaccines and Therapeutics Industry: SWOT Analysis
Figure 49: Global: mRNA Vaccines and Therapeutics Industry: Value Chain Analysis
Figure 50: Global: mRNA Vaccines and Therapeutics Industry: Porter’s Five Forces Analysis
List of Tables
Table 1: Global: mRNA Vaccines and Therapeutics Market Potential: Key Industry Highlights, 2022 and 2028
Table 2: Global: mRNA Vaccines and Therapeutics Market: List of Pipeline mRNA Vaccines
Table 3: Global: mRNA Vaccines and Therapeutics Market Potential: Breakup by Vaccine Type (in Billion US$), 2023-2028
Table 4: Global: mRNA Vaccines and Therapeutics Market Potential: Breakup by Treatment Type (in Billion US$), 2023-2028
Table 5: Global: mRNA Vaccines and Therapeutics Market Potential: Breakup by Vaccine Manufacturing (in Billion US$), 2023-2028
Table 6: Global: mRNA Vaccines and Therapeutics Market Potential: Breakup by Application (in Billion US$), 2023-2028
Table 7: Global: mRNA Vaccines and Therapeutics Market Potential: Breakup by End-User (in Billion US$), 2023-2028
Table 8: Global: mRNA Vaccines and Therapeutics Market Potential: Breakup by Region (in Billion US$), 2023-2028
Table 9: Global: mRNA Vaccines and Therapeutics Market: Competitive Structure
Table 10: Global: mRNA Vaccines and Therapeutics Market: List of Key Players
Companies Mentioned
- Arcturus Therapeutics Inc.
- BioNTech SE
- CureVac AG
- eTheRNA immunotherapies NV
- ethris GmbH
- GlaxoSmithKline PLC
- Moderna Therapeutics Inc.
- Translate Bio Inc.
- Argos Therapeutics
- Inc.
- Sangamo Therapeutics Inc.
- Pfizer Inc
Methodology
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